Search Results - "Salapatek, Anne Marie F"

The Multiple Actions of GLP-1 on the Process of Glucose-Stimulated Insulin Secretion by MacDonald, Patrick E, El-Kholy, Wasim, Riedel, Michael J, Salapatek, Anne Marie F, Light, Peter E, Wheeler, Michael B

“…The Multiple Actions of GLP-1 on the Process of Glucose-Stimulated Insulin Secretion Patrick E. MacDonald 1 , Wasim El-kholy 1 , Michael J. Riedel 2 , Anne…”
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Generation of a Phenotypic Array of Hypothalamic Neuronal Cell Models to Study Complex Neuroendocrine Disorders by Belsham, Denise D, Cai, Fang, Cui, Hong, Smukler, Simon R, Salapatek, Anne Marie F, Shkreta, Lulzim

“…Knowledge of how the brain achieves its diverse central control of basic physiology is severely limited by the virtual absence of appropriate cell models…”
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Exogenous Nitric Oxide and Endogenous Glucose-Stimulated β-Cell Nitric Oxide Augment Insulin Release by Smukler, Simon R, Tang, Lan, Wheeler, Michael B, Salapatek, Anne Marie F

“…Exogenous Nitric Oxide and Endogenous Glucose-Stimulated β-Cell Nitric Oxide Augment Insulin Release Simon R. Smukler 1 , Lan Tang 1 , Michael B. Wheeler 1 2…”
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The 25-kDa Synaptosome-associated Protein (SNAP-25) Binds and Inhibits Delayed Rectifier Potassium Channels in Secretory Cells by Ji, Junzhi, Tsuk, Sharon, Salapatek, Anne Marie F., Huang, Xiaohang, Chikvashvili, Dodo, Pasyk, Ewa A., Kang, Youhou, Sheu, Laura, Tsushima, Robert, Diamant, Nicholas, Trimble, William S., Lotan, Ilana, Gaisano, Herbert Y.

“…Delayed-rectifier K+ channels (KDR) are important regulators of membrane excitability in neurons and neuroendocrine cells. Opening of these voltage-dependent…”
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Pollinex Quattro: a novel and well-tolerated, ultra short-course allergy vaccine by Patel, Piyush, Salapatek, Anne Marie F

“…Pollinex Quattro is a novel, ultra short-course vaccine for treatment of seasonal allergic rhinitis from grass, tree or ragweed pollen allergy. Its unique…”
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SNAP-25, a SNARE protein, inhibits two types of K+ channels in esophageal smooth muscle by Ji, Junzhi, Salapatek, Anne Marie F., Lau, Helena, Wang, Guotang, Gaisano, Herbert Y., Diamant, Nicholas E.

“…The plasma membrane-associated soluble N-ethyl male! mide-sensitive factors attachment protein receptors (SNARES), synaptosome-associated protein of 25…”
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Ion channel diversity in the feline smooth muscle esophagus by Salapatek, Anne Marie F, Ji, Junzhi, Diamant, Nicholas E

“…We have characterized ion-channel identity and density differences along the feline smooth muscle esophagus using patch-clamp recording. Current clamp…”
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Increased uncoupling protein-2 levels in β-cells are associated with impaired glucose-stimulated insulin secretion: Mechanism of action by CHAN, Catherine B, DE LEO, Domenica, JOSEPH, Jamie W, MCQUAID, Timothy S, XIAO FANG HA, FANG XU, TSUSHIMA, Robert G, PENNEFATHER, Peter S, SALAPATEK, Anne Marie F, WHEELER, Michael B

“…In pancreatic beta-cells, glucose metabolism signals insulin secretion by altering the cellular array of messenger molecules. ATP is particularly important,…”
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Non-clinical pharmacology, pharmacokinetics, and safety findings for the antihistamine bepotastine besilate by Williams, Jon I., Gow, James A., Klier, Sharon M., McCue, Shannon L., Salapatek, Anne Marie F., McNamara, Timothy R.

“…Abstract Scope: The purpose of this review is to examine published non-clinical literature on the antihistamine bepotastine besilate, including pharmacokinetic…”
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Glucagon-like peptide-1 receptor activation antagonizes voltage-dependent repolarizing K(+) currents in beta-cells: a possible glucose-dependent insulinotropic mechanism by MacDonald, Patrick E, Salapatek, Anne Marie F, Wheeler, Michael B

“…Glucagon-like peptide-1 (GLP-1) acts through its G-protein-coupled receptor to enhance glucose-stimulated insulin secretion from pancreatic beta-cells. This is…”
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Synaptosome-Associated Protein of 25 Kilodaltons Modulates Kv2.1 Voltage-Dependent K+ Channels in Neuroendocrine Islet β-Cells through an Interaction with the Channel N Terminus by MacDonald, Patrick E, Wang, Guotang, Tsuk, Sharon, Dodo, Chikvashvili, Kang, Youhou, Tang, Lan, Wheeler, Michael B, Cattral, Mark S, Lakey, Jonathan R. T, Salapatek, Anne Marie F, Lotan, Ilana, Gaisano, Herbert Y

“…Insulin secretion is initiated by ionic events involving membrane depolarization and Ca2+ entry, whereas exocytic SNARE (soluble N-ethylmaleimide-sensitive…”
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Temperature and redox state dependence of native Kv2.1 currents in rat pancreatic β‐cells by MacDonald, Patrick E., Salapatek, Anne Marie F., Wheeler, Michael B.

“…In pancreatic β‐cells, voltage‐dependent K+ (Kv) channels repolarise glucose‐stimulated action potentials. Kv channels are therefore negative regulators of…”
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Mutations to the Third Cytoplasmic Domain of the Glucagon-Like Peptide 1 (GLP-1) Receptor Can Functionally Uncouple GLP-1-Stimulated Insulin Secretion in HIT-T15 Cells by Salapatek, Anne Marie F, MacDonald, Patrick E, Gaisano, Herbert Y, Wheeler, Michael B

“…Glucagon-like peptide-1 (GLP-1) is an insulinotropic hormone with powerful antidiabetogenic effects that are thought to be mediated by adenylyl cyclase (AC)…”
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Glucagon-Like Peptide-1 Receptor Activation Antagonizes Voltage-Dependent Repolarizing K+ Currents in β-Cells by MacDonald, Patrick E., Salapatek, Anne Marie F., Wheeler, Michael B.

“…Glucagon-like peptide-1 (GLP-1) acts through its G-protein-coupled receptor to enhance glucose-stimulated insulin secretion from pancreatic β-cells. This is…”
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Potassium channel diversity within the muscular components of the feline lower esophageal sphincter by Salapatek, Anne Marie F, Ji, Junzhi, Muinuddin, Ahmad, Diamant, Nicholas E

“…We hypothesized that regional differences in electrophysiological properties exist within the musculature of the feline lower esophageal sphincter (LES) and…”
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Myogenic NOS in canine lower esophageal sphincter: enzyme activation, substrate recycling, and product actions by Salapatek, A M, Wang, Y F, Mao, Y K, Mori, M, Daniel, E E

“…Depolarization elicited outward K+ currents from canine lower esophageal sphincter (LES) muscle cells, primarily through iberiotoxin (IbTX)- and…”
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Calcium source diversity in canine lower esophageal sphincter muscle by Salapatek, A M, Lam, A, Daniel, E E

“…Tonic contraction of the lower esophageal sphincter (LES) prevents gastroesophageal reflux. LES tone is produced both by cholinergic nerve and myogenic…”
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Myogenic nitric oxide synthase activity in canine lower oesophageal sphincter: morphological and functional evidence by Salapatek, Anne Marie F., Wang, Yu‐Fang, Mao, Yu‐Kang, Lam, Annette, Daniel, Edwin E.

“…1 Studies on canine lower oesophageal sphincter (LOS) evaluated the existence and function of a myogenic, nitric oxide synthase (NOS) by use of…”
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Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane by Gaisano, Herbert Y., Lutz, Manfred P., Leser, Juergen, Sheu, Laura, Lynch, Grit, Tang, Lan, Tamori, Yoshikazu, Trimble, William S., Salapatek, Anne Marie F.

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Increased Uncoupling Protein-2 Levels in β-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion by Chan, Catherine B., De Leo, Domenica, Joseph, Jamie W., McQuaid, Timothy S., Ha, Xiao Fang, Xu, Fang, Tsushima, Robert G., Pennefather, Peter S., Salapatek, Anne Marie F., Wheeler, Michael B.

“…Increased Uncoupling Protein-2 Levels in β-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion Mechanism of Action Catherine B. Chan 1 ,…”
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