Search Results - "Salamone, John"

The Mysterious Motivational Functions of Mesolimbic Dopamine by Salamone, John D., Correa, Mercè

“…Nucleus accumbens dopamine is known to play a role in motivational processes, and dysfunctions of mesolimbic dopamine may contribute to motivational symptoms…”
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Functions of mesolimbic dopamine: changing concepts and shifting paradigms by Salamone, John D

“…Issue Title: Dopamine - revisited…”
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The Neurobiology of Activational Aspects of Motivation: Exertion of Effort, Effort-Based Decision Making, and the Role of Dopamine by Salamone, John D, Correa, Mercè

“…Motivational processes are complex and multifaceted, with both directional and activational aspects. Behavioral activation and exertion of effort are functions…”
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Differentiating effort-related aspects of motivation from reinforcement learning: commentary on Soder et al. "Dose-response effects of d-amphetamine on effort-based decision-making and reinforcement learning" by Salamone, John D

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Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology by Salamone, John D, Yohn, Samantha E, López-Cruz, Laura, San Miguel, Noemí, Correa, Mercè

“…Motivation has been defined as the process that allows organisms to regulate their internal and external environment, and control the probability, proximity…”
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Brain mechanisms underlying apathy by Le Heron, Campbell, Holroyd, Clay B, Salamone, John, Husain, Masud

“…The past few decades have seen growing interest in the neuropsychiatric syndrome of apathy, conceptualised as a loss of motivation manifesting as a reduction…”
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Dopaminergic modulation of effort-related choice behavior as assessed by a progressive ratio chow feeding choice task: pharmacological studies and the role of individual differences by Randall, Patrick A, Pardo, Marta, Nunes, Eric J, López Cruz, Laura, Vemuri, V Kiran, Makriyannis, Alex, Baqi, Younis, Müller, Christa E, Correa, Mercè, Salamone, John D

“…Mesolimbic dopamine (DA) is involved in behavioral activation and effort-related processes. Rats with impaired DA transmission reallocate their instrumental…”
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Dopamine and Food Addiction: Lexicon Badly Needed by Salamone, John D, Correa, Mercè

“…Over the last few years, the concept of food addiction has become a common feature in the scientific literature, as well as the popular press. Nevertheless,…”
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Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: Effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors by NUNESA, Eric J, RANDALL, Patrick A, PODURGIEL, Samantha, CORREA, Mercè, SALAMONE, John D

“…Mesolimbic dopamine (DA) is a critical component of the brain circuitry regulating behavioral activation and effort-related processes. Although nucleus…”
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Caffeine and Selective Adenosine Receptor Antagonists as New Therapeutic Tools for the Motivational Symptoms of Depression by López-Cruz, Laura, Salamone, John D, Correa, Mercè

“…Major depressive disorder is one of the most common and debilitating psychiatric disorders. Some of the motivational symptoms of depression, such anergia (lack…”
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DA Neurons Promote the Instigation and Maintenance of Effortful Responding: A Commentary on Fischbach-Weiss, Reese, and Janak by Salamone, John D.

“…•This is a commentary on Fischbach-Weiss, Reese, and Janak.•Optogenetic inhibition of DA neurons inhibits initiation and maintenance of operant…”
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Measuring reinforcement learning and motivation constructs in experimental animals: Relevance to the negative symptoms of schizophrenia by Markou, Athina, Salamone, John D., Bussey, Timothy J., Mar, Adam C., Brunner, Daniela, Gilmour, Gary, Balsam, Peter

“…•Clarification of terms used in clinical and animal literature pertaining to negative symptoms of schizophrenia.•Description of experimental animal tasks to…”
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Patterns of Neural Responses, Pavlovian-to-Instrumental Transfer, and Prediction of Relapse by Salamone, John D., Correa, Merce

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Dopamine, Effort-Based Choice, and Behavioral Economics: Basic and Translational Research by Salamone, John D, Correa, Merce, Yang, Jen-Hau, Rotolo, Renee, Presby, Rose

“…Operant behavior is not only regulated by factors related to the quality or quantity of reinforcement, but also by the work requirements inherent in performing…”
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The Psychopharmacology of Effort-Related Decision Making: Dopamine, Adenosine, and Insights into the Neurochemistry of Motivation by Salamone, John D, Correa, Mercè, Ferrigno, Sarah, Yang, Jen-Hau, Rotolo, Renee A, Presby, Rose E

“…Effort-based decision making is studied using tasks that offer choices between high-effort options leading to more highly valued reinforcers versus…”
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Neurobiological basis of motivational deficits in psychopathology by Salamone, John D, Koychev, Ivan, Correa, Mercè, McGuire, Philip

“…Abstract In recent years, there has been increasing emphasis on the importance of motivational symptoms in depression, schizophrenia and other disorders. The…”
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Effects of the dopamine depleting agent tetrabenazine in tests evaluating different components of depressive-like behavior in mice: sex-dependent response to antidepressant drugs with SERT and DAT blocker profiles by Carratalá-Ros, Carla, Martínez-Verdú, Andrea, Olivares-García, Regulo, Salamone, John D., Correa, Mercè

“…Background Depression is a disorder twice as common in women than in men. There are sex differences in the symptomatology and treatment response to this…”
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Effects of lisdexamfetamine and s-citalopram, alone and in combination, on effort-related choice behavior in the rat by Yohn, Samantha E., Lopez-Cruz, Laura, Hutson, Peter H., Correa, Merce, Salamone, John D.

“…Rationale Effort-related motivational symptoms, such as anergia, psychomotor retardation, and fatigue, are an important aspect of depression and other…”
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The VMAT-2 inhibitor tetrabenazine affects effort-related decision making in a progressive ratio/chow feeding choice task: reversal with antidepressant drugs by Randall, Patrick A, Lee, Christie A, Nunes, Eric J, Yohn, Samantha E, Nowak, Victoria, Khan, Bilal, Shah, Priya, Pandit, Saagar, Vemuri, V Kiran, Makriyannis, Alex, Baqi, Younis, Müller, Christa E, Correa, Merce, Salamone, John D

“…Behavioral activation is a fundamental feature of motivation, and organisms frequently make effort-related decisions based upon evaluations of reinforcement…”
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Critical review of RDoC approaches to the study of motivation with animal models: effort valuation/willingness to work by Salamone, John D, Correa, Merce

“…The NIMH research domain criteria (RDoC) approach was instigated to refocus mental health research on the neural circuits that mediate psychological functions,…”
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