Search Results - "Salama, Abeer"

Chitosan based Pickering emulsion as a promising approach for topical application of rutin in a solubilized form intended for wound healing: In vitro and in vivo study by Asfour, Marwa Hasanein, Elmotasem, Heba, Mostafa, Dina Mahmoud, Salama, Abeer A.A.

“…[Display omitted] The aim of the present study is to formulate the hydrophobic drug rutin in a solubilized form, intended for wound healing, via its loading…”
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Colchicine mesoporous silica nanoparticles/hydrogel composite loaded cotton patches as a new encapsulator system for transdermal osteoarthritis management by Mohamed, Amina L., Elmotasem, Heba, Salama, Abeer A.A.

“…Colchicine is a drug from the past with a bright shining future. It has gained much attention nowadays due to the newly explored therapeutic avenues that were…”
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Promising targets of chrysin and daidzein in colorectal cancer: Amphiregulin, CXCL1, and MMP-9 by Salama, Abeer A.A., Allam, Rasha M.

“…Colorectal cancer is one of the primary causes of cancer-related mortality worldwide. The tumor microenvironment contains growth factors; inflammatory…”
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Coating with tripolyphosphate-crosslinked chitosan as a novel approach for enhanced stability of emulsomes following oral administration: Rutin as a model drug with improved anti-hyperlipidemic effect in rats by Asfour, Marwa Hasanein, Salama, Abeer A.A.

“…[Display omitted] The aim of the current study is to preserve the emulsomal vesicles against the harsh condition of gastrointestinal tract (GIT), after oral…”
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Single step nanospray drying preparation technique of gabapentin-loaded nanoparticles-mediated brain delivery for effective treatment of PTZ-induced seizures by Salama, Alaa H., Salama, Abeer A.A., Elhabak, Mona

“…[Display omitted] •Gabapentin loaded chitosan nanoparticles (107 nm) prepared using Nano Spray Dryer.•Intranasal Rhodamine labeled chitosan nanoparticles…”
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Nanotechnology based blended chitosan-pectin hybrid for safe and efficient consolidative antiemetic and neuro-protective effect of meclizine hydrochloride in chemotherapy induced emesis by Salama, Alaa H., Elmotasem, Heba, Salama, Abeer A.A.

“…[Display omitted] The aim of this study was to formulate an easily-administered, safe and effective dosage form loaded with meclizine for treatment of…”
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Hyaluronate functionalized Span-Labrasol nanovesicular transdermal therapeutic system of ferulic acid targeting diabetic nephropathy by Elmotasem, Heba, Salama, Abeer A.A., Shalaby, Eman Samy

“…Diabetic kidney disease, known as diabetic nephropathy (DN), is a widespread severe diabetes complication leading to kidney failure. Due to the lack of…”
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Eplerenone modulates the inflammatory response in monosodium iodoacetate-induced knee osteoarthritis in rats: Involvement of RANKL/OPG axis by Mostafa, Rasha E., Salama, Abeer A.A.

“…Osteoarthritis (OA) is a multifactorial degenerative disease marked by the progressive deterioration of articular cartilage with inflammation of the synovium…”
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In vitro and in vivo evaluation of an oral sustained release hepatoprotective caffeine loaded w/o Pickering emulsion formula – Containing wheat germ oil and stabilized by magnesium oxide nanoparticles by Elmotasem, Heba, Farag, Hala K., Salama, Abeer A.A.

“…[Display omitted] The objective of this study was to innovate an effective oral sustained release hepatoprotective formula for – the water soluble drug –…”
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Nose-to-brain delivery of galantamine loaded nanospray dried polyacrylic acid/taurodeoxycholate mixed matrix as a protective therapy in lipopolysaccharide-induced Alzheimer’s in mice model by Elhabak, Mona, Salama, Abeer A.A., Salama, Alaa H.

“…[Display omitted] •Galantamine is loaded into polyacrylic acid/taurodeoxycholate mixed matrix.•Galantamine loaded nanoparticles are prepared using Nano Spray…”
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Improved hepatoprotective activity of silymarin via encapsulation in the novel vesicular nanosystem bilosomes by Mohsen, Amira Mohamed, Asfour, Marwa Hasanein, Salama, Abeer A. A.

“…The main objective of the present work was to formulate, characterize, and evaluate silymarin (SM)-loaded bilosomes, compared to conventional liposomes, aiming…”
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Intranasal Chromium Induces Acute Brain and Lung Injuries in Rats: Assessment of Different Potential Hazardous Effects of Environmental and Occupational Exposure to Chromium and Introduction of a Novel Pharmacological and Toxicological Animal Model by Salama, Abeer, Hegazy, Rehab, Hassan, Azza

“…Chromium (Cr) is used in many industries and it is widely distributed in the environment. Exposure to Cr dust has been reported among workers at these…”
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Naringin protects mice from D-galactose-induced lung aging and mitochondrial dysfunction: Implication of SIRT1 pathways by Salama, Abeer A.A., Yassen, Noha N., Mansour, Heba M.

“…Aging is the leading risk factor for diminishing lung function, as well as injury and lung disorder. The target of our research was to examine the potential…”
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Protocatechuic acid ameliorates lipopolysaccharide‐induced kidney damage in mice via downregulation of TLR‐4‐mediated IKBKB/NF‐κB and MAPK/Erk signaling pathways by Salama, Abeer A. A., Elgohary, Rania, Fahmy, Mohamed Ibrahim

“…Acute kidney injury (AKI) is a very critical cause of death in the whole world. Lipopolysaccharide (LPS) induces kidney damage by activating various…”
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Micellar buccal film for safe and effective control of seizures: Preparation, in vitro characterization, ex vivo permeation studies and in vivo assessment by Salama, Alaa H., Basha, Mona, Salama, Abeer A.A.

“…The current research article focused on formulating an easily applied, water-based buccal film loaded with the antiepileptic drug, lamotrigine (LTG). The…”
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Renoprotective Effect of Lactoferrin against Chromium-Induced Acute Kidney Injury in Rats: Involvement of IL-18 and IGF-1 Inhibition by Hegazy, Rehab, Salama, Abeer, Mansour, Dina, Hassan, Azza

“…Hexavalent chromium (CrVI) is a heavy metal widely used in more than 50 industries. Nephrotoxicity is a major adverse effect of chromium poisoning. The present…”
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Rutin loaded bilosomes for enhancing the oral activity and nephroprotective effects of rutin in potassium dichromate induced acute nephrotoxicity in rats by Mohsen, Amira Mohamed, Wagdi, Marwa Anwar, Salama, Abeer

“…Rutin, a flavone glycoside, has shown to have a significant beneficial kidney protection effect in drug-induced nephropathy. However, its poor solubility and…”
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Budesonide-Loaded Bilosomes as a Targeted Delivery Therapeutic Approach Against Acute Lung Injury in Rats by Salem, Heba F, Moubarak, Ghada Abdelsabour, Ali, Adel A, Salama, Abeer A A, Salama, Alaa H

“…Budesonide (BUD), a glucocorticoids drug, inhibits all steps in the inflammatory response. It can reduce and treat inflammation and other symptoms associated…”
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Cubosome-based thermosensitive in situ gelling system for intranasal administration of lamotrigine with enhanced antiepileptic efficacy by Mohsen, Amira Mohamed, Salama, Abeer A. A., Asfour, Marwa Hasanein

“…Lamotrigine (LTG) is a second-generation antiepileptic drug that belongs to Biopharmaceutics Classification System (BCS) class II. LTG has a low probability of…”
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Hepato- and neuro-protective influences of biopropolis on thioacetamide-induced acute hepatic encephalopathy in rats by Mostafa, Rasha E, Salama, Abeer A A, Abdel-Rahman, Rehab F, Ogaly, Hanan A

“…Hepatic encephalopathy (HE) is a neuropsychiatric syndrome that ultimately occurs as a complication of acute or chronic liver failure; accompanied by…”
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