Search Results - "Salama, AD"

Genetically Distinct Subsets within ANCA-Associated Vasculitis by Lyons, Paul A, Rayner, Tim F, Trivedi, Sapna, Holle, Julia U, Watts, Richard A, Jayne, David R.W, Baslund, Bo, Brenchley, Paul, Bruchfeld, Annette, Chaudhry, Afzal N, Cohen Tervaert, Jan Willem, Deloukas, Panos, Feighery, Conleth, Gross, Wolfgang L, Guillevin, Loic, Gunnarsson, Iva, Harper, Lorraine, Hrušková, Zdenka, Little, Mark A, Martorana, Davide, Neumann, Thomas, Ohlsson, Sophie, Padmanabhan, Sandosh, Pusey, Charles D, Salama, Alan D, Sanders, Jan-Stephan F, Savage, Caroline O, Segelmark, Mårten, Stegeman, Coen A, Tesař, Vladimir, Vaglio, Augusto, Wieczorek, Stefan, Wilde, Benjamin, Zwerina, Jochen, Rees, Andrew J, Clayton, David G, Smith, Kenneth G.C

“…This study confirms the presence of a genetic component of the pathogenesis of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis and genetic…”
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Rituximab in adult minimal change disease and focal segmental glomerulosclerosis - What is known and what is still unknown? by Gauckler, Philipp, Shin, Jae Il, Alberici, Federico, Audard, Vincent, Bruchfeld, Annette, Busch, Martin, Cheung, Chee Kay, Crnogorac, Matija, Delbarba, Elisa, Eller, Kathrin, Faguer, Stanislas, Galesic, Kresimir, Griffin, Siân, Hrušková, Zdenka, Jeyabalan, Anushya, Karras, Alexandre, King, Catherine, Kohli, Harbir Singh, Maas, Rutger, Mayer, Gert, Moiseev, Sergey, Muto, Masahiro, Odler, Balazs, Pepper, Ruth J., Quintana, Luis F., Radhakrishnan, Jai, Ramachandran, Raja, Salama, Alan D., Segelmark, Mårten, Tesař, Vladimír, Wetzels, Jack, Willcocks, Lisa, Windpessl, Martin, Zand, Ladan, Zonozi, Reza, Kronbichler, Andreas

“…Primary forms of minimal change disease and focal segmental glomerulosclerosis are rare podocytopathies and clinically characterized by nephrotic syndrome…”
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Outcome and treatment of elderly patients with ANCA-associated vasculitis by Weiner, Maria, Goh, Su Mein, Mohammad, Aladdin J, Hruskova, Zdenka, Tanna, Anisha, Bruchfeld, Annette, Selga, Daina, Chocova, Zdenka, Westman, Kerstin, Eriksson, Per, Pusey, Charles D, Tesar, Vladimir, Salama, Alan D, Segelmark, Mårten

“…ANCA-associated vasculitis is commonly found in elderly patients, but there are few data concerning outcome and treatment in the highest age groups…”
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Sirolimus use in patients with subglottic stenosis in the context of granulomatosis with polyangiitis (GPA), suspected GPA, and immunoglobulin G 4 -related disease by Poo, S X, Pepper, R J, Onwordi, L, Ghufoor, K, Sandhu, G, Salama, A D

“…: Subglottic stenosis (SGS) is a severe, life-threatening disease found in immune-mediated diseases such as granulomatosis with polyangiitis (GPA) and in rare…”
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Comparison of outcomes using the rituximab originator MabThera with the biosimilar Truxima in patients with ANCA-associated vasculitis by Antonelou, M, Abro, A, Heath, R, Iacovou, A, Ashley, C, Caplan, J, Morgan, M D, Logan, S, Harper, L, Salama, A D

“…The use of rituximab (MabThera®), an anti-CD20 monoclonal antibody, is the most significant development in the management of anti-neutrophil cytoplasm antibody…”
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Effect of Treatment on Damage and Hospitalization in Elderly Patients with Microscopic Polyangiitis and Granulomatosis with Polyangiitis by Weiner, Maria, Goh, Su Mein, Mohammad, Aladdin J, Hrušková, Zdenka, Tanna, Anisha, Sharp, Phoebe, Kang, Amy, Bruchfeld, Annette, Selga, Daina, Chocová, Zdeňka, Westman, Kerstin, Eriksson, Per, Harper, Lorraine, Pusey, Charles D, Tesař, Vladimír, Salama, Alan D, Segelmark, Mårten

“…Age is a risk factor for organ damage, adverse events, and mortality in microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA). However, the…”
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Experimental Autoimmune Vasculitis: An Animal Model of Anti-neutrophil Cytoplasmic Autoantibody-Associated Systemic Vasculitis by Little, Mark A, Smyth, Lucy, Salama, Alan D, Mukherjee, Sriparna, Smith, Jennifer, Haskard, Dorian, Nourshargh, Sussan, Cook, H. Terence, Pusey, Charles D

“…The morbidity burden associated with anti-neutrophil cytoplasmic autoantibody-associated vasculitis is increasing, and many novel biological therapies are now…”
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The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice by Ansari, Mohammed Javeed I, Salama, Alan D, Chitnis, Tanuja, Smith, R Neal, Yagita, Hideo, Akiba, Hisaya, Yamazaki, Tomohide, Azuma, Miyuki, Iwai, Hideyuki, Khoury, Samia J, Auchincloss, Jr, Hugh, Sayegh, Mohamed H

“…Programmed death-1 (PD-1) receptor, an inhibitory costimulatory molecule found on activated T cells, has been demonstrated to play a role in the regulation of…”
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Rituximab in Membranous Nephropathy by Gauckler, Philipp, Shin, Jae Il, Alberici, Federico, Audard, Vincent, Bruchfeld, Annette, Busch, Martin, Cheung, Chee Kay, Crnogorac, Matija, Delbarba, Elisa, Eller, Kathrin, Faguer, Stanislas, Galesic, Kresimir, Griffin, Siân, van den Hoogen, Martijn W.F., Hrušková, Zdenka, Jeyabalan, Anushya, Karras, Alexandre, King, Catherine, Kohli, Harbir Singh, Mayer, Gert, Maas, Rutger, Muto, Masahiro, Moiseev, Sergey, Odler, Balazs, Pepper, Ruth J., Quintana, Luis F., Radhakrishnan, Jai, Ramachandran, Raja, Salama, Alan D., Schönermarck, Ulf, Segelmark, Mårten, Smith, Lee, Tesař, Vladimír, Wetzels, Jack, Willcocks, Lisa, Windpessl, Martin, Zand, Ladan, Zonozi, Reza, Kronbichler, Andreas, Gauckler, Philipp, Shin, Jae Il, Alberici, Federico, Audard, Vincent, Bruchfeld, Annette, Busch, Martin, Cheung, Chee Kay, Crnogorac, Matija, Delbarba, Elisa, Eller, Kathrin, Faguer, Stanislas, Galesic, Kresimir, Griffin, Siân, van den Hoogen, Martijn W.F., Hrušková, Zdenka, Jeyabalan, Anushya, Karras, Alexandre, King, Catherine, Kohli, Harbir Singh, Mayer, Gert, Maas, Rutger, Muto, Masahiro, Moiseev, Sergey, Odler, Balazs, Pepper, Ruth J., Quintana, Luis F., Radhakrishnan, Jai, Ramachandran, Raja, Salama, Alan D., Schönermarck, Ulf, Segelmark, Mårten, Smith, Lee, Tesař, Vladimír, Wetzels, Jack, Willcocks, Lisa, Windpessl, Martin, Zand, Ladan, Zonozi, Reza, Kronbichler, Andreas

“…Membranous nephropathy (MN) is the most common cause of primary nephrotic syndrome among adults. The identification of phospholipase A2 receptor (PLA2R) as…”
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Update on antiglomerular basement membrane disease by Peto, Philippa, Salama, Alan D

“…PURPOSE OF REVIEWAntiglomerular basement membrane (GBM) disease is a rare form of autoimmune glomerulonephritis often accompanied by lung haemorrhage and…”
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Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis by Salama, Alan D, Chitnis, Tanuja, Imitola, Jaime, Ansari, Mohammed Javeed I, Akiba, Hisaya, Tushima, Fumihiko, Azuma, Miyuki, Yagita, Hideo, Sayegh, Mohamed H, Khoury, Samia J

“…Experimental autoimmune encephalomyelitis (EAE) is mediated by autoantigen-specific T cells dependent on critical costimulatory signals for their full…”
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Regulatory functions of CD8+CD28– T cells in an autoimmune disease model by Najafian, Nader, Chitnis, Tanuja, Salama, Alan D., Zhu, Bing, Benou, Christina, Yuan, Xueli, Clarkson, Michael R., Sayegh, Mohamed H., Khoury, Samia J.

“…CD8 + T cell depletion renders CD28-deficient mice susceptible to experimental autoimmune encephalomyelitis (EAE). In addition, CD8 –/– CD28 –/–…”
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Drug Insight: rituximab in renal disease and transplantation by Salama, Alan D, Pusey, Charles D

“…Rituximab, a monoclonal antibody directed against the CD20 molecule found on pre-B cells and mature B cells (but not on plasma cells), was introduced in the…”
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An Analysis of Lymphocyte Phenotype After Steroid Avoidance With Either Alemtuzumab or Basiliximab Induction in Renal Transplantation by Cherukuri, A., Salama, A. D., Carter, C., Smalle, N., McCurtin, R., Hewitt, E. W., Hernandez‐Fuentes, M., Clark, B., Baker, R. J.

“…Several studies have analyzed the phenotype of repopulated T‐lymphocytes following alemtuzumab induction; however there has been less scrutiny of the…”
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Regulatory CD25+ T cells in human kidney transplant recipients by SALAMA, Alan D, NAJAFIAN, Nader, CLARKSON, Michael R, HARMON, William E, SAYEGH, Mohamed H

“…Recent evidence suggests that a population of professional regulatory cells, which limit immune responsiveness, exist in rodents and healthy human subjects…”
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The association of serum calprotectin (S100A8/S100A9) levels with disease relapses in PR3-ANCA-associated vasculitis by Pepper, Ruth J, Draibe, Juliana B, Caplin, Ben, Fervenza, Fernando C, Hoffman, Gary S, Kallenberg, Cees G.M, Langford, Carol A, Monach, Paul A, Seo, Philip, Spiera, Robert, St Clair, E. William, Tchao, Nadia K, Stone, John H, Specks, Ulrich, Merkel, Peter A, Salama, AD

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The role of novel T cell costimulatory pathways in autoimmunity and transplantation by YAMADA, Akira, SALAMA, Alan D, SAYEGH, Mohamed H

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Role of the Programmed Death-1 Pathway in Regulation of Alloimmune Responses In Vivo by Sandner, Sigrid E, Clarkson, Michael R, Salama, Alan D, Sanchez-Fueyo, Alberto, Domenig, Christoph, Habicht, Antje, Najafian, Nader, Yagita, Hideo, Azuma, Miyuki, Turka, Laurence A, Sayegh, Mohamed H

“…Programmed death-1 (PD-1), an inhibitory receptor up-regulated on activated T cells, has been shown to play a critical immunoregulatory role in peripheral…”
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Transplant Accommodation in Highly Sensitized Patients: A Potential Role for Bcl‐xL and Alloantibody by Salama, Alan D., Delikouras, Alex, Pusey, Charles D., Cook, H. Terrance, Bhangal, Gurjeet, Lechler, Robert I., Dorling, Anthony

“…Transplantation of renal allografts into recipients with circulating anti‐HLA antibodies results in hyperacute rejection. In some cases, however, antibodies…”
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Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis by Chitnis, T, Najafian, N, Benou, C, Salama, A D, Grusby, M J, Sayegh, M H, Khoury, S J

“…Experimental autoimmune encephalomyelitis (EAE) is mediated by myelin-specific CD4(+) T cells secreting Th1 cytokines, while recovery from disease is…”
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