Search Results - "Salako, Michael A"
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A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment
Published in Cancer research (Chicago, Ill.) (01-01-2012)“…Constitutive production of inflammatory cytokines is a characteristic of many human malignant cell lines; however, the in vitro and in vivo interdependence of…”
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p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker
Published in Molecular cancer (03-07-2010)“…The oncolytic adenovirus dl922-947 replicates selectively within and lyses cells with a dysregulated Rb pathway, a finding seen in > 90% human cancers…”
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Coxsackievirus Protein 2BC Blocks Host Cell Apoptosis by Inhibiting Caspase-3
Published in The Journal of biological chemistry (16-06-2006)“…Virus infection may induce host cell death by apoptosis, but some DNA viruses are capable of preventing this process. RNA viruses were thought not to display…”
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Inhibition of the Inflammatory Cytokine TNF-α Increases Adenovirus Activity in Ovarian Cancer via Modulation of cIAP1/2 Expression
Published in Molecular therapy (01-03-2011)“…Oncolytic adenoviruses show promise as a cancer treatment. However, they generate acute inflammatory responses with production of cytokines, including tumor…”
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Human herpesvirus 1 protein US3 induces an inhibition of mitochondrial electron transport
Published in Journal of general virology (01-08-2006)“…School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK Correspondence Michael J. Carter m.carter{at}surrey.ac.uk Previous…”
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Abstract 591: Host cell DNA damage and inflammation responses determine oncolytic adenovirus efficacy in ovarian cancer
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Introduction. Oncolytic adenoviruses show promise as a cancer treatment, by replicating selectively within malignant cells. Viral replication requires…”
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Inhibition of the Inflammatory Cytokine TNF-[alpha] Increases Adenovirus Activity in Ovarian Cancer via Modulation of cIAP1/2 Expression
Published in Molecular therapy (01-03-2011)“…Oncolytic adenoviruses show promise as a cancer treatment. However, they generate acute inflammatory responses with production of cytokines, including tumor…”
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Human herpesvirus 1 protein U sub(S)3 induces an inhibition of mitochondrial electron transport
Published in Journal of general virology (01-08-2006)“…Previous studies have identified virus proteins that traffic to mitochondria and may affect mitochondrial function. Here, it is reported that Human herpesvirus…”
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