Search Results - "Sakyi, Samuel"
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Association between adverse pregnancy outcome and imbalance in angiogenic regulators and oxidative stress biomarkers in gestational hypertension and preeclampsia
Published in BMC pregnancy and childbirth (25-08-2015)“…Gestational hypertension (GH) and Preeclampsia, (PE) are the most complicated amongst hypertensive disorders of pregnancy. The mechanism that links…”
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2
Evaluating immunohaematological profile among COVID-19 active infection and recovered patients in Ghana
Published in PloS one (12-09-2022)“…Introduction The rapid spread of COVID-19 has been a global public health problem and it is yet to be put under control. Active COVID-19 is associated with…”
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3
RNA Aptamer That Specifically Binds to Mycolactone and Serves as a Diagnostic Tool for Diagnosis of Buruli Ulcer
Published in PLoS neglected tropical diseases (24-10-2016)“…Buruli ulcer (BU) is a subcutaneous skin disease listed among the neglected tropical diseases by the World Health Organization (WHO). Early case detection and…”
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4
Evaluating Vitamin D Status in Pre- and Postmenopausal Type 2 Diabetics and Its Association with Glucose Homeostasis
Published in BioMed research international (01-01-2018)“…Background. Type 2 Diabetes Mellitus (T2DM) and menopause are associated with vitamin D status. Oestrogen decline during menopausal stages promotes…”
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5
Seroconversion of Hepatitis B Vaccine in Young Children in the Kassena Nankana District of Ghana: A Cross-Sectional Study
Published in PloS one (30-12-2015)“…Hepatitis B Virus (HBV) infection is an important public health problem that requires high priority efforts towards prevention and control. Active immunization…”
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Evaluation of Immune Characteristics and Factors Associated with Immune Response following Hepatitis B Vaccination among Ghanaian Adolescents
Published in Advances in virology (24-05-2024)“…Background. WHO recommends HBV-negative babies in high-prevalence (8%) countries receive anti-HBV vaccination. Ghana initiated mass immunization in 2002, but…”
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Seroprevalence and risk factors of Hepatitis B and Hepatitis C infections among pregnant women in the Asante Akim North Municipality of the Ashanti region, Ghana; a cross sectional study
Published in African health sciences (01-09-2015)“…Background: Viral hepatitis is a serious public health problem affecting billions of people globally with maternal-fetal transmission on the rise. Objectives:…”
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Interplay between vitamin D status, vitamin D receptor gene variants and preeclampsia risk in Ghanaian women: A case-control study
Published in PloS one (30-05-2024)“…Preeclampsia (PE) is characterized by hypertension and proteinuria mostly after 20 weeks of gestation. It affects 2-8% of pregnancies worldwide, with…”
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9
Targeting the SARS-CoV2 nucleocapsid protein for potential therapeutics using immuno-informatics and structure-based drug discovery techniques
Published in Biomedicine & pharmacotherapy (01-12-2020)“…[Display omitted] •404SKQLQQSMSSADS416 and 92RRIRGGDGKMKDL104 sequences of N-protein are predicted to induce B-cell memory response .•79SSPDDQIGY87 and…”
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10
Single nucleotide polymorphisms in LCAT may contribute to dyslipidaemia in HIV-infected individuals on HAART in a Ghanaian population
Published in Scientific reports (10-11-2020)“…Highly active antiretroviral therapy (HAART) is known to cause lipid abnormalities such as dyslipidaemia in HIV-infected individuals. Yet, dyslipidaemia may…”
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11
Clinical and Laboratory Diagnosis of Buruli Ulcer Disease: A Systematic Review
Published in The Canadian journal of infectious diseases & medical microbiology (01-01-2016)“…Background. Buruli ulcer (BU) is a necrotizing cutaneous infection caused by Mycobacterium ulcerans. Early diagnosis is crucial to prevent morbid effects and…”
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12
Association between endothelial nitric oxide synthase (eNOS) gene variants and nitric oxide production in preeclampsia: a case–control study in Ghana
Published in Scientific reports (07-09-2023)“…Evidence suggests that a major cause of PE is endothelial dysfunction emanating from the reduced bioavailability of Nitric oxide (NO). Variants of endothelial…”
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13
Acute kidney injury in pediatric patients with malaria: A prospective cross-sectional study in the shai-osudoku district of Ghana
Published in Saudi journal of kidney diseases and transplantation (01-01-2020)“…Acute kidney injury (AKI) is a highly fatal complication of malaria. We used the Kidney Disease Improving Global Outcomes (KDIGO) and Pediatric Risk, Injury,…”
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Assessing the role of eosinophil‐mediated immune response markers in detecting hookworm infection: A case‐control study in Kintampo, Ghana
Published in Health science reports (01-07-2022)“…Background and Aim Human hookworm disease caused by Ancylostoma duodenale and Necator americanus is a serious public health problem. Hookworm infection…”
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15
Increased metformin dosage suppresses pro-inflammatory cytokine levels in systemic circulation and might contribute to its beneficial effects
Published in Journal of immunoassay & immunochemistry (04-05-2021)“…Type 2 Diabetes Mellitus (T2DM) is a metabolic disorder, characterized by persistent elevation of blood glucose either due to insulin resistance or insulin…”
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16
Comparative Assessment of Knowledge, Attitudes, and Practice of Breast Self-Examination among Female Secondary and Tertiary School Students in Ghana
Published in International journal of breast cancer (01-01-2018)“…Background. Breast cancer remains a serious public health problem globally. It is particularly increasing among adolescents and premenopausal women. Breast…”
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17
Profiling vitamin D, its mediators and proinflammatory cytokines in rheumatoid arthritis: A case–control study
Published in Immunity, Inflammation and Disease (01-08-2022)“…Introduction The active form of vitamin D has immunomodulatory and anti‐inflammatory effect. Vitamin D is implicated in pathogenesis of rheumatoid arthritis…”
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18
Frailty syndrome and associated factors among patients with hypertension: A cross‐sectional study in Kumasi, Ghana
Published in Health science reports (01-10-2023)“…Background and Aim Frailty is a condition marked by accumulation of biological deficits and dysfunctions that come with aging and it is correlated with high…”
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Evaluating the Contribution of Nocardia spp. and Mycobacterium tuberculosis to Pulmonary Infections among HIV and Non-HIV Patients at the Komfo Anokye Teaching Hospital, Ghana
Published in The Canadian journal of infectious diseases & medical microbiology (01-01-2018)“…Tuberculosis (TB) is a major cause of human mortality particularly in association with the human immunodeficiency virus (HIV). Nocardia spp. has emerged as an…”
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Plasmodium falciparum coinfection is associated with improved IgE and IgG3 response against hookworm antigens
Published in Health science reports (01-07-2022)“…Background Plasmodium falciparum and Hookworm infections are prevalent in West Africa and they cause iron deficiency anemia and protein malnutrition in…”
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