Search Results - "Sakuma, Hiroyuki"

Pediatric Stevens–Johnson syndrome associated with severe acute respiratory syndrome coronavirus 2 infection by Haraguchi, Shotaro, Tsubokura, Shin, Ozasa, Koji, Sakuma, Hiroyuki, Ito, Shuichi

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Anti-sortilin1 Antibody Up-Regulates Progranulin via Sortilin1 Down-Regulation by Miyakawa, Shuuichi, Sakuma, Hiroyuki, Warude, Dnyaneshwar, Asanuma, Satomi, Arimura, Naoto, Yoshihara, Tomoki, Tavares, Daniel, Hata, Akito, Ida, Koh, Hori, Yuri, Okuzono, Yuumi, Yamamoto, Syunsuke, Iida, Koichi, Shimizu, Hisao, Kondo, Shinichi, Sato, Shuji

“…Progranulin (PGRN) haploinsufficiency associated with loss-of-function mutations in the granulin gene causes frontotemporal dementia (FTD). This suggests that…”
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Reduced TREM2 activation in microglia of patients with Alzheimer's disease by Okuzono, Yuumi, Sakuma, Hiroyuki, Miyakawa, Shuuichi, Ifuku, Masataka, Lee, Jonghun, Das, Debashree, Banerjee, Antara, Zhao, Yang, Yamamoto, Koji, Ando, Tatsuya, Sato, Shuji

“…Loss‐of‐function variants of triggering receptor expressed on myeloid cells 2 (TREM2) increase the risk of developing Alzheimer's disease (AD). The mechanism…”
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Fatal warm autoimmune hemolytic anemia in a child due to IgM‐type autoantibodies by Takahashi, Hiroyuki, Tanaka, Fumiko, Sakuma, Hiroyuki, Sato, Mutsumi, Inaba, Shoichi, Kai, Sumio

“…Herein is described a case of immunoglobulin M (IgM) warm autoimmune hemolytic anemia (AIHA) in a child who consequently died within 3 days of clinical onset…”
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Pharmacological Properties of FK886, a New, Centrally Active Neurokinin-1 Receptor Antagonist by Yoshino-Furukawa, Takako, Maeda, Yasue, Kikuchi, Aya, Sakuma, Hiroyuki, Imazumi, Katsunori, Yamakuni, Hisashi, Sogabe, Hajime, Matsuo, Masahiko, Manda, Toshitaka, Uchida, Wataru

“…The pharmacological properties of the novel neurokinin-1 (NK1) receptor antagonist FK886,…”
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FK614, a Novel Peroxisome Proliferator-Activated Receptor γ Modulator, Induces Differential Transactivation Through a Unique Ligand-Specific Interaction With Transcriptional Coactivators by Fujimura, Takao, Sakuma, Hiroyuki, Konishi, Satoko, Oe, Tomoya, Hosogai, Naomi, Kimura, Chiaki, Aramori, Ichiro, Mutoh, Seitaro

“…Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-dependent transcriptional factor implicated in regulating adipogenesis, glucose homeostasis,…”
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fMRI measurement of the integrative effects of visual and chemical senses stimuli in humans by Tonoike, Mitsuo, Yoshida, Tatsuya, Sakuma, Hiroyuki, Wang, Li-Qun

“…The purpose of this study was to evaluate the integrative effects of visual stimuli with chemical senses (olfactory and gustatory) stimuli in humans…”
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Unique Properties of Coactivator Recruitment Caused by Differential Binding of FK614, an Anti-diabetic Agent, to Peroxisome Proliferator-Activated Receptor γ by Fujimura, Takao, Sakuma, Hiroyuki, Ohkubo-Suzuki, Akiko, Aramori, Ichiro, Mutoh, Seitaro

“…FK614 is a structurally novel class of peroxisome proliferator-activated receptor γ (PPARγ) agonist, with the mechanism of its insulin-sensitizing action most…”
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Case of follicular mucinosis: Nestin‐expression in mucin‐producing cells by SAKUMA, Hiroyuki, AMOH, Yasuyuki, NIIYAMA, Shiro, KANOH, Maho, KATSUOKA, Kensei

“…A 29‐year‐old Japanese man had an asymptomatic, solitary, indurated, erythematous plaque measuring 30 mm × 30 mm on his jaw that had been present for a month…”
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Cloning and Chromosomal Mapping of Human Glucuronyltransferase Involved in Biosynthesis of the HNK-1 Carbohydrate Epitope by Mitsumoto, Yasuhiro, Oka, Shogo, Sakuma, Hiroyuki, Inazawa, Johji, Kawasaki, Toshisuke

“…The HNK-1 carbohydrate is expressed on various cell adhesion molecules in the nervous system and is suggested to play a role in cell–cell and cell–substrate…”
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Molecular Cloning and Functional Expression of a cDNA Encoding a New Member of Mixed Lineage Protein Kinase from Human Brain by Sakuma, Hiroyuki, Ikeda, Atsushi, Oka, Shogo, Kozutsumi, Yasunori, Zanetta, Jean-Pierre, Kawasaki, Toshisuke

“…We have cloned a novel protein kinase from human cerebellum and named it LZK (leucine zipper-bearing kinase). The LZK cDNA encoded a 966-amino acid polypeptide…”
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Pediatric Stevens‐Johnson Syndrome associated with SARS‐CoV‐2 infection by Haraguchi, Shotaro, Tsubokura, Shin, Ozasa, Koji, Sakuma, Hiroyuki, Ito, Shuichi

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THE PREVALENCE OF ALCOHOL, NICOTINE, HYPNOTIC ABUSE IN THE EARTHQUAKE AND TSUNAMI STRICKEN AREA IN JAPAN by Kimura, Mitsuru, Sakuma, Hiroyuki, Matsushita, Sachio

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A selective peroxisome proliferator-activated receptor gamma modulator with distinct fat cell regulation properties by Fujimura, Takao, Kimura, Chiaki, Oe, Tomoya, Takata, Yoko, Sakuma, Hiroyuki, Aramori, Ichiro, Mutoh, Seitaro

“…Adipogenesis is an important process for the improvement of insulin resistance by peroxisome proliferator-activated receptor (PPAR) gamma agonists, such as…”
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ACCEPTANCE OF CONTROLLED DRINK-ING AS A TREATMENT GOAL OF ALCOHOL DEPENDENCE: CURRENT CONDITIONS IN JAPAN by Takimura, Tsuyoshi, Maesato, Hitoshi, Nakayama, Hideki, Sakuma, Hiroyuki, Yoshimura, Atsushi, Tohyama, Tomomi, Kimura, Mitsuru, Matsushita, Sachio, Higuchi, Susumu

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Gastric mucosal resistance and prostanoid levels after cimetidine treatment in rats by Arakawa, T, Satoh, H, Fukuda, T, Sakuma, H, Nakamura, H, Kobayashi, K

“…We studied the effects of cimetidine administered intraperitoneally to rats at a dose of 20 mg/kg twice daily for 7 days on gastric mucosal integrity and…”
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Unique Properties of Coactivator Recruitment Caused by Differential Binding of FK614, an Anti-diabetic Agent, to Peroxisome Proliferator-Activated Receptor [gamma] by Fujimura, Takao, Sakuma, Hiroyuki, Ohkubo-Suzuki, Akiko, Aramori, Ichiro, Mutoh, Seitaro

“…FK614 is a structurally novel class of peroxisome proliferator-activated receptor γ (PPARγ) agonist, with the mechanism of its insulin-sensitizing action most…”
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The effect of FK1052 on methotrexate-induced delayed emesis in dogs by Yamakuni, Hisashi, Sawai, Hiroe, Imazumi, Katsunori, Maeda, Yasue, Sakuma, Hiroyuki, Matsuo, Masahiko, Mutoh, Seitaro

“…Delayed emesis in cancer patients undergoing chemotherapy remains a significant problem. The pathogenesis of delayed emesis is still obscure. It was recently…”
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Reactivity of Half Esters of Polyhydric Alcohol with Amine by Nakamura, Hiroyuki, Sakuma, Hiroyuki, Ogata, Naoya

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Role of mucosal leukotriene in mucosal damage caused by 0.6N HCL in rat stomach by Sakuma, H, Nakamura, H, Kobayashi, K, Fukuda, T, Sato, H

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