Search Results - "Sakr, Sharif"

Molecular classification of endometrial carcinoma applied to endometrial biopsy specimens: Towards early personalized patient management by Abdulfatah, Eman, Wakeling, Erin, Sakr, Sharif, Al-Obaidy, Khaleel, Bandyopadhyay, Sudeshna, Morris, Robert, Feldman, Gerald, Ali-Fehmi, Rouba

“…AbstractBackgroundThe current risk stratification systems used to guide management of endometrial cancer are based on irreproducible post surgical pathological…”
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Ovarian cancer modulates the immunosuppressive function of CD11b+Gr1+ myeloid cells via glutamine metabolism by Udumula, Mary P., Sakr, Sharif, Dar, Sajad, Alvero, Ayesha B., Ali-Fehmi, Rouba, Abdulfatah, Eman, Li, Jing, Jiang, Jun, Tang, Amy, Buekers, Thomas, Morris, Robert, Munkarah, Adnan, Giri, Shailendra, Rattan, Ramandeep

“…Immature CD11b + Gr1+ myeloid cells that acquire immunosuppressive capability, also known as myeloid-derived suppressor cells (MDSCs), are a heterogeneous…”
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Granulosa Cell Tumors: Novel Predictors of Recurrence in Early-stage Patients by Sakr, Sharif, Abdulfatah, Eman, Thomas, Sumi, Al-wahab, Zaid, Beydoun, Rafic, Morris, Robert, Ali-Fehmi, Rouba, Bandyopadhyay, Sudeshna

“…Granulosa cell tumors (GCTs) comprise 2% to 5% of ovarian neoplasms, with unpredictable patterns of recurrence. The HER family, GATA4, and SMAD3 genes are…”
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Prenatal Diagnosis of Congenital Dermal Sinus by Sakr, Sharif, Mohan, Yedathore, Malik, Asif, Malik, Ghaus, Gonik, Bernard

“…Background Congenital dermal sinus (CDS) is an uncommon form of spinal dysraphism. Although postdelivery identification in the neonate is aided by several…”
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Endometriosis Impairs Bone Marrow-Derived Stem Cell Recruitment to the Uterus Whereas Bazedoxifene Treatment Leads to Endometriosis Regression and Improved Uterine Stem Cell Engraftment by Sakr, Sharif, Naqvi, Hanyia, Komm, Barry, Taylor, Hugh S

“…Endometriosis is a disease defined by the ectopic growth of uterine endometrium. Stem cells contribute to the generation of endometriosis as well as to repair…”
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Abstract B32: Myeloid-derived suppressor cell depletion augments antitumor activity in ovarian cancer by Sakr, Sharif, Dar, Sajad, Giri, Shailendra, Munkarah, Adnan, Rattan, Ramandeep

“…Abstract Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that are increased in tumors and create an…”
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Treatment with bazedoxifene and conjugated estrogens results in regression of endometriosis in a murine model by Naqvi, Hanyia, Sakr, Sharif, Presti, Thomas, Krikun, Graciela, Komm, Barry, Taylor, Hugh S

“…Bazedoxifene (BZA), a selective estrogen receptor modulator (SERM), inhibits the action of estrogens on endometrial proliferation. Here, we evaluate the effect…”
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Epithelial Ovarian Cancer microenvironment regulates Myeloid cell metabolism to confer immunosuppression via glutamine metabolism by Udumula, Mary Priyanka, Sakr, Sharif, Dar, Sajad, Morris, Robert, Buekers, Thomas, Munkarah, Adnan, Giri, Shailendra, Rattan, Ramandeep

“…Abstract Myeloid Cells are a major constituent of epithelial ovarian cancer (EOC) microenvironment that confer immunosuppression and promote tumor growth…”
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Myeloid derived suppressor cells promote ovarian cancer progression in a murine model of ovarian cancer by Rattan, Ramandeep, Sakr, Sharif, Dar, Sajad, Buekars, Thomas, Morris, Robert, Munkarah, Adnan, Giri, Shailendra

“…Abstract Myeloid Derived Suppressor Cells (MDSCs) are a heterogeneous population of immature myeloid cells that create an immunosuppressive environment by…”
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Abstract 378: Stat3 promotes ovarian cancer by modulating the energy metabolism and develops drug resistance in patients by Raja, Vaishnavi, Giri, Shailendra, Sakr, Sharif, Hijaz, Miriana, Quiles, Raymond, Munkarah, Adnan R., Rattan, Ramandeep

“…Abstract Signal Transducers and Activators of Transcription (STAT) are a group of transcription factors that are known to play a major role in cancer…”
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Abstract 4735: Role of myeloid derived suppressor cells in promoting ovarian cancer by Rattan, Ramandeep, Sakr, Sharif, Quiles, Raymond, Morris, Robert, Buekers, Thomas, Munkarah, Adnan, Giri, Shailendra

“…Abstract Myeloid Derived Suppressor Cells (MDSCs) are a heterogeneous population of immature myeloid cells that are increased in tumors and create an…”
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Clear Cell Carcinoma of the Endometrium: Evaluation of Prognostic Parameters in a Multi-institutional Cohort of 165 Cases by Abdulfatah, Eman, Sakr, Sharif, Thomas, Sumi, Al-Wahab, Zaid, Mutch, David G, Dowdy, Sean, Bandyopadhyay, Sudeshna, Munkarah, Adnan, Elshaikh, Mohamed, Morris, Robert, Ali-Fehmi, Rouba

“…Clear cell carcinoma (CCC) comprises a rare yet an aggressive subtype, accounting for less than 5% of all uterine carcinomas. Several clinicopathologic…”
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Uterine tachysystole in spontaneous labor at term by Ahmed, Ahmed I., Zhu, Ling, Aldhaheri, Sarah, Sakr, Sharif, Minkoff, Howard, Haberman, Shoshana

“…Objectives: The objective of this study is to determine the incidence of uterine tachysystole and its association with spontaneous labor at term. Methods: A…”
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Divergent Metabolic Effects of Metformin Merge to Enhance Eicosapentaenoic Acid Metabolism and Inhibit Ovarian Cancer In Vivo by Udumula, Mary P, Poisson, Laila M, Dutta, Indrani, Tiwari, Nivedita, Kim, Seongho, Chinna-Shankar, Jasdeep, Allo, Ghassan, Sakr, Sharif, Hijaz, Miriana, Munkarah, Adnan R, Giri, Shailendra, Rattan, Ramandeep

“…Metformin is being actively repurposed for the treatment of gynecologic malignancies including ovarian cancer. We investigated if metformin induces analogous…”
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A Simplified Risk Stratification Method for Women With Stage I Endometrial Carcinoma by Elshaikh, Mohamed A, Modh, Ankit, Sakr, Sharif, Shrestha, Resha, Burmeister, Charlotte, Ali-Fehmi, Rouba, Hanna, Rabbie K

“…Available risk stratification methods for women with endometrial carcinoma are controversially defined. We sought to develop a simplified and an individualized…”
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Treatment with Bazedoxifene and Conjugated Estrogens Results in Regression of Endometriosis in a Murine Model1 by Naqvi, Hanyia, Sakr, Sharif, Presti, Thomas, Krikun, Graciela, Komm, Barry, Taylor, Hugh S

“…Bazedoxifene (BZA), a selective estrogen receptor modulator (SERM), inhibits the action of estrogens on endometrial proliferation. Here, we evaluate the effect…”
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Outcomes following intra-amniotic instillation with indigo carmine to diagnose prelabor rupture of membranes in singleton pregnancies: a single center experience by Adekola, Henry, Gill, Navleen, Sakr, Sharif, Hobson, Deslyn, Bryant, David, Abramowicz, Jacques S., Soto, Eleazar

“…Objective: To evaluate clinical outcomes of women with singleton pregnancies that underwent intra-amniotic dye instillation (amniodye test) following equivocal…”
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The impact of digoxin on mortality in patients with chronic systolic heart failure: A propensity – Matched cohort study by Al-khateeb, May, Qurashi, Waqas T, Odeh, Raed, Ahmed, Amjad M, Sakr, Sharif, Elshawi, Radwa, Bdier, M. Bassam, Al-Mallah, Mouaz H

“…Abstract Background Prior Studies showed mixed results in association of digoxin use with all-cause mortality (ACM). The aim of this analysis is to identify…”
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Antenatal sonographic appearance of a large orbital encephalocele: A case report and differential diagnosis of orbital cystic mass by Ahmed, Ahmed, Noureldin, Rehab, Gendy, Mohamed, Sakr, Sharif, Abdel Naby, Mahmoud

“…Orbital meningoceles and encephaloceles are rare extracranial extensions of the brain and meninges with or without direct communication between the central…”
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Prenatal Diagnosis of Congenital Dermal Sinus by Sakr, Sharif, Mohan, Yedathore, Malik, Asif, Malik, Ghaus, Gonik, Bernard

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