Search Results - "Sakr, Hussein F."
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Low-Carbohydrate Ketogenic Diet for Improvement of Glycemic Control: Mechanism of Action of Ketosis and Beneficial Effects
Published in Current diabetes reviews (01-01-2023)“…The incidence of metabolic syndrome and diabetes mellitus is increasing globally. A diet rich in carbohydrates increases the hyperglycemic state. While…”
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Insulin Resistance and Hypertension: Mechanisms Involved and Modifying Factors for Effective Glucose Control
Published in Biomedicines (01-08-2023)“…Factors such as aging, an unhealthy lifestyle with decreased physical activity, snacking, a standard Western diet, and smoking contribute to raising blood…”
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Resveratrol Reverses Cadmium Chloride-induced Testicular Damage and Subfertility by Downregulating p53 and Bax and Upregulating Gonadotropins and Bcl-2 gene Expression
Published in Journal of Reproduction and Development (2014)“…This study was performed to investigate the protective and therapeutic effects of resveratrol (RES) against CdCl2-induced toxicity in rat testes. Seven…”
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Effect of valsartan on cardiac senescence and apoptosis in a rat model of cardiotoxicity
Published in Canadian journal of physiology and pharmacology (01-06-2016)“…The clinical application of doxorubicin is limited by its cardiotoxicity. The present study investigated the effect of valsartan on doxorubicin-induced…”
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Dehydroepiandrosterone (DHEA) Improves the Metabolic and Haemostatic Disturbances in Rats with Male Hypogonadism
Published in Scientia pharmaceutica (01-03-2022)“…Objectives: The current work was designed to study the effect of dehydroepiandrosterone (DHEA) on glucose homeostasis, liver functions and hemostatic…”
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The Impact of Intermittent Fasting on Brain-Derived Neurotrophic Factor, Neurotrophin 3, and Rat Behavior in a Rat Model of Type 2 Diabetes Mellitus
Published in Brain sciences (15-02-2021)“…Type 2 diabetes mellitus (T2DM) is known to be associated with an increased risk of dementia, specifically Alzheimer's disease and vascular dementia…”
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Impact of Dehydroepiandrosterone (DHEA) on Bone Mineral Density and Bone Mineral Content in a Rat Model of Male Hypogonadism
Published in Veterinary sciences (23-11-2020)“…The present study examined the effect DHEA (dehydroepiandrosterone) on bone mineral content (BMC) and bone mineral density (BMD) and biomarkers of bone…”
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Possible mechanisms underlying fatty liver in a rat model of male hypogonadism: A protective role for testosterone
Published in Steroids (01-07-2018)“…[Display omitted] •ORCD causes visceral obesity, dyslipidemia, impaired GT and insulin resistance.•ORCD increases the activity of liver enzymes that increase…”
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Chronic valproic acid administration enhances oxidative stress, upregulates IL6 and downregulates Nrf2, Glut1 and Glut4 in rat’s liver and brain
Published in Neuroreport (07-07-2021)“…Valproic acid (VPA) is a powerful antiepileptic drug that was associated with several neurological and hepatic problems especially with increasing its dose and…”
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Location-Linked QR Code as a Safe Tool for Recording Classroom Attendance During COVID-19 Pandemic: Perspectives of Medical Students
Published in Medical science educator (01-10-2022)“…COVID-19 lockdowns affected educational programs. Online learning has suddenly become the main form of medical education. However, attendance enhances a…”
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Resveratrol Modulates Bone Mineral Density and Bone Mineral Content in A Rat Model of Male Hypogonadism
Published in Chinese journal of integrative medicine (01-02-2023)“…Objective To determine whether resveratrol (Res) can correct osteoporosis induced in a rat model of male hypogonadism. Methods Thirty-two rats were randomly…”
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Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism
Published in Canadian journal of physiology and pharmacology (01-04-2016)“…Inflammation is a major risk factor for cardiovascular complications. Magnesium sulfate (MgSO4) has anti-inflammatory actions. Therefore we investigated the…”
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Effect of selenium and grape seed extract on indomethacin-induced gastric ulcers in rats
Published in Journal of physiology and biochemistry (01-09-2013)“…Indomethacin (IND) is a non-steroid anti-inflammatory agent that is known to induce severe gastric mucosal lesions. In this study, we investigated the…”
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Simvastatin and vitamin E effects on cardiac and hepatic oxidative stress in rats fed on high fat diet
Published in Journal of physiology and biochemistry (01-12-2013)“…High fat diet (HFD) is a common cause of metabolic syndrome and type 2 diabetes mellitus. Published data showed that HFD and subsequent dyslipidemia are major…”
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Swim exercise inhibits hemostatic abnormalities in a rat model of obesity and insulin resistance
Published in Archives of physiology and biochemistry (01-01-2019)“…Background: We sought to determine whether swim exercise can inhibit high carbohydrate and fat diet (HCFD)-induced biomarkers of coagulation and thrombosis…”
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Melatonin Improves Memory Deficits in Rats with Cerebral Hypoperfusion, Possibly, Through Decreasing the Expression of Small-Conductance Ca2+-Activated K+ Channels
Published in Neurochemical research (01-08-2019)“…This study investigated the expression pattern, regulation of expression, and the role of hippocampal small-conductance Ca 2+ -activated K + (SK) channels in…”
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Modulation of the neurological and vascular complications by grape seed extract in a rat model of spinal cord ischemia-reperfusion injury by downregulation of both osteopontin and cyclooxygenase-2
Published in Canadian journal of physiology and pharmacology (01-07-2016)“…In this study, we investigated the effects of grape seed extract (GSE) on the expression of osteopontin (OPN) and cyclooxygenase-2 (COX-2) in a rat model of…”
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Effect of Resveratrol on Neurotrophic Factors and Depression-Like Behavior in a Rat Model of Male Hypogonadism
Published in International journal of pharmacology (15-01-2021)Get full text
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Possible Underlying Mechanisms of the Renoprotective Effect of Remote Limb Ischemic Preconditioning Against Renal Ischemia/Reperfusion Injury: A Role of Osteopontin, Transforming Growth Factor-Beta and Survivin
Published in Nephron (2015) (2016)“…It has been documented that remote limb ischemic preconditioning (rIPC) protect kidneys against renal ischemia/reperfusion (I/R). We hypothesized that…”
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