Search Results - "Sakati, Wayne"

EDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer by Bradley, Amber, Zheng, Hui, Ziebarth, Angela, Sakati, Wayne, Branham-O’Connor, Melissa, Blumer, Joe B., Liu, Yuying, Kistner-Griffin, Emily, Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Sood, Anil K., Landen, Charles N., Eblen, Scott T.

“…Summary We show that the E3 ubiquitin ligase EDD/UBR5 regulates both survival and cisplatin resistance in ovarian cancer cells and is a novel therapeutic…”
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ERK activation and nuclear signaling induced by the loss of cell/matrix adhesion stimulates anchorage-independent growth of ovarian cancer cells by Al-Ayoubi, Adnan, Tarcsafalvi, Adel, Zheng, Hui, Sakati, Wayne, Eblen, Scott T.

“…Ovarian cancer metastasis involves the sloughing of epithelial cells from the ovary into the peritoneal cavity, where the cells can survive and proliferate in…”
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Abstract 1649: The E3 ubiquitin ligase EDD regulates platinum resistance and is a novel therapeutic target for epithelial ovarian cancer by Bradley, Amber T., Zheng, Hui, Ziebarth, Angela, Sakati, Wayne, Eier, Sande, Lopez-Berestein, Gabriel, Sood, Anil K., Landen, Charles, Eblen, Scott T.

“…Abstract Introduction: Ovarian cancer is treated with a combination of surgery and chemotherapeutics, including taxol and platinum agents. A major difficulty…”
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Allelic exclusion of the TCR alpha-chain is an active process requiring TCR-mediated signaling and c-Cbl by Niederberger, Nathalie, Holmberg, Kaisa, Alam, S Munir, Sakati, Wayne, Naramura, Mayumi, Gu, Hua, Gascoigne, Nicholas R J

“…Phenotypic allelic exclusion at the TCRalpha locus is developmentally regulated in thymocytes. Many immature thymocytes express two cell surface alpha-chain…”
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Mutations in a Putative Zinc-Binding Domain Inactivate the Mitochondrial Intermediate Peptidase by Chew, Anne, Rollins, Robert A., Sakati, Wayne R., Isaya, Grazia

“…The mitochondrial intermediate peptidase (MIP) cleaves characteristic octapeptides, (F/L/I)XX(T/S/G)XXXX(↓), from the N-terminus of many imported mitochondrial…”
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Mammalian Mitochondrial Intermediate Peptidase: Structure/Function Analysis of a New Homologue from Schizophyllum commune and Relationship to Thimet Oligopeptidases by Isaya, Grazia, Sakati, Wayne R., Rollins, Robert A., Shen, Guang P., Hanson, Lee Q., Ullrich, Robert C., Novotny, Charles P.

“…Mitochondrial intermediate peptidase (MIP) is a component of the mitochondrial protein import machinery required for maturation of nuclear-encoded precursor…”
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Allelic Exclusion of the TCR {alpha}-Chain Is an Active Process Requiring TCR-Mediated Signaling and c-Cbl by Niederberger, Nathalie, Holmberg, Kaisa, Alam, S. Munir, Sakati, Wayne, Naramura, Mayumi, Gu, Hua, Gascoigne, Nicholas R. J

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