Search Results - "Sakamoto, Ryuichi"

Bilirubin reduces visceral obesity and insulin resistance by suppression of inflammatory cytokines by Takei, Ryoko, Inoue, Tomoaki, Sonoda, Noriyuki, Kohjima, Motoyuki, Okamoto, Misato, Sakamoto, Ryuichi, Inoguchi, Toyoshi, Ogawa, Yoshihiro

“…Although previous studies have reported a negative relationship between serum bilirubin concentration and the development of diabetes mellitus (DM), the…”
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Impact of helium and hydrogen plasma exposure on surface damage and erosion of tungsten by Sakamoto, Ryuichi, Bernard, Elodie, Kreter, Arkadi, Martin, Céline

“…Abstract The impact of helium plasma exposure on the tungsten surface damage structure development and erosion has been investigated by comparing the impact of…”
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Human leucocyte antigen DR15, a possible predictive marker for immune checkpoint inhibitor–induced secondary adrenal insufficiency by Yano, Seiichi, Ashida, Kenji, Sakamoto, Ryuichi, Sakaguchi, Chihiro, Ogata, Masatoshi, Maruyama, Kengo, Sakamoto, Shohei, Ikeda, Munehiko, Ohe, Kenji, Akasu, Shoko, Iwata, Shimpei, Wada, Nobuhiko, Matsuda, Yayoi, Nakanishi, Yoichi, Nomura, Masatoshi, Ogawa, Yoshihiro

“…Immune checkpoint inhibitors (ICPis) induce various immune-related adverse events (irAEs), despite their beneficial effects in treating various advanced…”
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Investigating the causal effect of fibroblast growth factor 23 on osteoporosis and cardiometabolic disorders: A Mendelian randomization study by Yokomoto-Umakoshi, Maki, Umakoshi, Hironobu, Miyazawa, Takashi, Ogata, Masatoshi, Sakamoto, Ryuichi, Ogawa, Yoshihiro

“…Pathological excess of fibroblast growth factor 23 (FGF23) causes mineral and bone disorders. However, the causality of FGF23 in the development of…”
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Machine learning based models for prediction of subtype diagnosis of primary aldosteronism using blood test by Kaneko, Hiroki, Umakoshi, Hironobu, Ogata, Masatoshi, Wada, Norio, Iwahashi, Norifusa, Fukumoto, Tazuru, Yokomoto-Umakoshi, Maki, Nakano, Yui, Matsuda, Yayoi, Miyazawa, Takashi, Sakamoto, Ryuichi, Ogawa, Yoshihiro

“…Primary aldosteronism (PA) is associated with an increased risk of cardiometabolic diseases, especially in unilateral subtype. Despite its high prevalence, the…”
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Non-alcoholic fatty liver disease in mice with hepatocyte-specific deletion of mitochondrial fission factor by Takeichi, Yukina, Miyazawa, Takashi, Sakamoto, Shohei, Hanada, Yuki, Wang, Lixiang, Gotoh, Kazuhito, Uchida, Keiichiro, Katsuhara, Shunsuke, Sakamoto, Ryuichi, Ishihara, Takaya, Masuda, Keiji, Ishihara, Naotada, Nomura, Masatoshi, Ogawa, Yoshihiro

“…Aims/hypothesis Mitochondria are highly dynamic organelles continuously undergoing fission and fusion, referred to as mitochondrial dynamics, to adapt to…”
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High frequency of germline recombination in Nestin-Cre transgenic mice crossed with Glucagon-like peptide 1 receptor floxed mice by Kajitani, Yusuke, Miyazawa, Takashi, Inoue, Tomoaki, Kajitani, Nao, Fujita, Masamichi, Takeichi, Yukina, Miyachi, Yasutaka, Sakamoto, Ryuichi, Ogawa, Yoshihiro

“…The Cre-loxP strategy for tissue-specific gene inactivation has become a widely employed tool in several research studies. Conversely, inadequate breeding and…”
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Role of Aldosterone and Potassium Levels in Sparing Confirmatory Tests in Primary Aldosteronism by Umakoshi, Hironobu, Sakamoto, Ryuichi, Matsuda, Yayoi, Yokomoto-Umakoshi, Maki, Nagata, Hiromi, Fukumoto, Tazuru, Ogata, Masatoshi, Ogawa, Yoshihiro

“…Abstract Context The current clinical guidelines suggest that confirmatory tests for primary aldosteronism (PA) may be excluded in some of patients who have…”
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Differential effect of canagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, on slow and fast skeletal muscles from nondiabetic mice by Otsuka, Hiroko, Yokomizo, Hisashi, Nakamura, Shintaro, Izumi, Yoshihiro, Takahashi, Masatomo, Obara, Sachiko, Nakao, Motonao, Ikeda, Yosuke, Sato, Naoichi, Sakamoto, Ryuichi, Miyachi, Yasutaka, Miyazawa, Takashi, Bamba, Takeshi, Ogawa, Yoshihiro

“…There has been a concern that sodium-glucose cotransporter 2 (SGLT2) inhibitors could reduce skeletal muscle mass and function. Here, we examine the effect of…”
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Impact of Cortisol on Reduction in Muscle Strength and Mass: A Mendelian Randomization Study by Katsuhara, Shunsuke, Yokomoto-Umakoshi, Maki, Umakoshi, Hironobu, Matsuda, Yayoi, Iwahashi, Norifusa, Kaneko, Hiroki, Ogata, Masatoshi, Fukumoto, Tazuru, Terada, Eriko, Sakamoto, Ryuichi, Ogawa, Yoshihiro

“…Prolonged exposure to pathological cortisol, as in Cushing's syndrome causes various age-related disorders, including sarcopenia. However, it is unclear…”
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Machine learning-based models for predicting clinical outcomes after surgery in unilateral primary aldosteronism by Kaneko, Hiroki, Umakoshi, Hironobu, Ogata, Masatoshi, Wada, Norio, Ichijo, Takamasa, Sakamoto, Shohei, Watanabe, Tetsuhiro, Ishihara, Yuki, Tagami, Tetsuya, Iwahashi, Norifusa, Fukumoto, Tazuru, Terada, Eriko, Katsuhara, Shunsuke, Yokomoto-Umakoshi, Maki, Matsuda, Yayoi, Sakamoto, Ryuichi, Ogawa, Yoshihiro

“…Unilateral subtype of primary aldosteronism (PA) is a common surgically curable form of endocrine hypertension. However, more than half of the patients with PA…”
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Effects of azilsartan compared with telmisartan on insulin resistance in patients with essential hypertension and type 2 diabetes mellitus: An open-label, randomized clinical trial by Naruse, Mitsuhide, Koike, Yasuhiro, Kamei, Nozomu, Sakamoto, Ryuichi, Yambe, Yuko, Arimitsu, Michinori

“…Based on non-clinical data, it is expected that azilsartan, an angiotensin II receptor blocker, will help improve insulin resistance in addition to its…”
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Protective Role of DHEAS in Age-related Changes in Bone Mass and Fracture Risk by Yokomoto-Umakoshi, Maki, Umakoshi, Hironobu, Iwahashi, Norifusa, Matsuda, Yayoi, Kaneko, Hiroki, Ogata, Masatoshi, Fukumoto, Tazuru, Terada, Eriko, Nakano, Yui, Sakamoto, Ryuichi, Ogawa, Yoshihiro

“…Dehydroepiandrosterone sulfate (DHEAS) from the adrenal cortex substantially decreases with age, which may accelerate osteoporosis. However, the association of…”
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Prospects for Self-Burning Operation in Heliotron-Type Fusion Reactor by Sakamoto, Ryuichi, Yamada, Hiroshi

“…Possible gaps between the current large helical device (LHD) experiment and the reactor operation have been investigated using the dynamic profile…”
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Impact of coronavirus disease 2019 on medical practice in endocrine and metabolic diseases in Japan: a nationwide surveillance study conducted by the Japan Endocrine Society by Manaka, Katsunori, Kato, Sayaka, Sakamoto, Ryuichi, Yamakage, Hajime, Uema, Tsugumi, Kawai, Shiori, Shibata, Megumi, Hiratsuka, Izumi, Nakachi, Sawako, Onoue, Takeshi, Tsuchiya, Takefumi, Fukui, Michiaki, Hashimoto, Koshi, Suzuki, Atsushi, Makita, Noriko, Ogawa, Yoshihiro, Arima, Hiroshi, Satoh-Asahara, Noriko, Masuzaki, Hiroaki

“…We investigated the impact of the Coronavirus disease 2019 (COVID-19) pandemic on the management of endocrine and metabolic disorders in Japan. We conducted a…”
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Unilateral primary aldosteronism as an independent risk factor for vertebral fracture by Yokomoto‐Umakoshi, Maki, Sakamoto, Ryuichi, Umakoshi, Hironobu, Matsuda, Yayoi, Nagata, Hiromi, Fukumoto, Tazuru, Ogata, Masatoshi, Ogawa, Yoshihiro

“…Context Primary aldosteronism (PA) is known to increase vertebral fracture (VF), although the detailed mechanism remains to be elucidated. We hypothesized that…”
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Surgical Treatment for Primary Brainstem Hemorrhage to Improve Postoperative Functional Outcomes by Ichimura, Shinya, Bertalanffy, Helmut, Nakaya, Masato, Mochizuki, Yoichi, Moriwaki, Goroku, Sakamoto, Ryuichi, Fukuchi, Masahito, Fujii, Koji

“…It remains controversial whether primary brainstem hemorrhage (PBH) should be managed conservatively or treated promptly by surgical evacuation of the…”
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Significance of Discordant Results Between Confirmatory Tests in Diagnosis of Primary Aldosteronism by Fukumoto, Tazuru, Umakoshi, Hironobu, Ogata, Masatoshi, Yokomoto-Umakoshi, Maki, Matsuda, Yayoi, Motoya, Misato, Nagata, Hiromi, Nakano, Yui, Iwahashi, Norifusa, Kaneko, Hiroki, Wada, Norio, Miyazawa, Takashi, Sakamoto, Ryuichi, Ogawa, Yoshihiro

“…Abstract Context Current clinical guidelines recommend confirmation of a positive result in at least one confirmatory test in the diagnosis of primary…”
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Genetic Analysis of Pheochromocytoma and Paraganglioma Complicating Cyanotic Congenital Heart Disease by Ogasawara, Tatsuki, Fujii, Yoichi, Kakiuchi, Nobuyuki, Shiozawa, Yusuke, Sakamoto, Ryuichi, Ogawa, Yoshihiro, Ootani, Katsuki, Ito, Etsuro, Tanaka, Tomoaki, Yoshida, Yusaku, Kimura, Noriko, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Ogawa, Seishi

“…Abstract Context Pheochromocytoma and paraganglioma (PPGL) may appear as a complication of cyanotic congenital heart disease (CCHD-PPGL) with frequent EPAS1…”
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Do multiple types of confirmatory tests improve performance in predicting subtypes of primary aldosteronism? by Kaneko, Hiroki, Umakoshi, Hironobu, Fukumoto, Tazuru, Wada, Norio, Ichijo, Takamasa, Sakamoto, Shohei, Watanabe, Tetsuhiro, Ishihara, Yuki, Tagami, Tetsuya, Ogata, Masatoshi, Iwahashi, Norifusa, Yokomoto‐Umakoshi, Maki, Matsuda, Yayoi, Sakamoto, Ryuichi, Ogawa, Yoshihiro

“…Objective The clinical practice guideline for primary aldosteronism (PA) places a high value on confirmatory tests to sparing patients with false‐positive…”
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