Search Results - "Sakamaki, Akira"
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1
Long-term efficacy and safety of nalfurafine hydrochloride on pruritus in chronic liver disease patients: Patient-reported outcome based analyses
Published in PloS one (12-06-2017)“…Among various symptoms accompanied with chronic liver disease, pruritus affects the quality of life of patients, causing physical and mental stress, and…”
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2
Rapidly declining skeletal muscle mass predicts poor prognosis of hepatocellular carcinoma treated with transcatheter intra-arterial therapies
Published in BMC cancer (24-07-2018)“…The impact of sarcopenia on the prognosis of patients with hepatocellular carcinoma (HCC) who receive transcatheter intra-arterial therapies, including…”
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3
Considerations of elderly factors to manage the complication of liver cirrhosis in elderly patients
Published in World journal of gastroenterology : WJG (21-04-2019)“…The aging of the organ function causes sensitivity to the disease progression and need careful consideration for the medical treatment. With the increase of…”
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4
Obesity and accumulation of subcutaneous adipose tissue are poor prognostic factors in patients with alcoholic liver cirrhosis
Published in PloS one (17-11-2020)“…In alcoholic liver cirrhosis (LC) patients, obesity has become a problem that progresses into liver dysfunction. Herein, we investigated the relationship…”
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5
Navitoclax improves acute‐on‐chronic liver failure by eliminating senescent cells in mice
Published in Hepatology research (01-05-2023)“…Aim Acute‐on‐chronic liver failure (ACLF), a disease with poor prognosis, is reportedly caused by cellular senescence due to mitochondrial dysfunction. In this…”
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6
Problems and future questions in the clinical practice of liver cirrhosis
Published in Nippon Shōkakibyō Gakkai zasshi (2021)Get more information
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7
Maid gene dysfunction promotes hyperobesity via the reduction of adipose tissue inflammation in Mc4r gene-deficient mice
Published in Scientific reports (10-09-2024)“…The onset and progression mechanisms of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis…”
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8
Hydrogen-producing small intestinal bacterial overgrowth is associated with hepatic encephalopathy and liver function
Published in PloS one (25-02-2022)“…Overt hepatic encephalopathy (HE) is one of the complications of liver cirrhosis (LC), which negatively affects the prognosis and quality of life of patients…”
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Effects of Atezolizumab and Bevacizumab on Adrenal Gland Metastasis of Hepatocellular Carcinoma: A Case Report and Review of Literature
Published in Internal Medicine (01-11-2022)“…Regarding the prognosis of cases with advanced-stage hepatocellular carcinoma (HCC), a recent clinical study showed that the immune checkpoint inhibitors…”
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10
Effect of Lenvatinib on a Hepatocellular Carcinoma with Fibroblast Growth Factor Receptor 4 Expression: A Case Report and Review of the Literature
Published in Internal Medicine (01-06-2021)“…Basic and clinical research have shown that the expression of molecules involved in the hepatocellular carcinoma (HCC) cell signaling pathway is related to the…”
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11
Portal venous gas caused by barium swallow examination: An extremely rare clinical finding
Published in Clinical case reports (01-07-2023)“…Key Clinical Message We found an extremely rare case of PVG after a barium swallow examination. This may be related to vulnerable intestinal mucosa in the…”
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12
Spontaneous regression of hepatocellular carcinoma: A mini-review
Published in World journal of gastroenterology : WJG (07-06-2017)“…Spontaneous tumor regression is an extremely rare phenomenon in the oncology field. However, there are several case reports resulted in the regression of…”
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13
Rare Mesenteric Arterial Diseases: Fibromuscular Dysplasia and Segmental Arterial Mediolysis and Literature Review
Published in Internal Medicine (01-12-2019)“…Fibromuscular dysplasia (FMD) and segmental arterial mediolysis (SAM) are noninflammatory, nonatherosclerotic arterial diseases that cause aneurysm, occlusion,…”
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14
Daisaikoto improves fatty liver and obesity in melanocortin-4 receptor gene-deficient mice via the activation of brown adipose tissue
Published in Scientific reports (16-06-2022)“…Melanocortin 4 receptor gene-knockout (MC4R-KO) mice are known to develop obesity with a high-fat diet. Meanwhile, daisaikoto, one of Kampo medicines, is a…”
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15
Longitudinal increase in albumin-bilirubin score is associated with non-malignancy-related mortality and quality of life in patients with liver cirrhosis
Published in PloS one (03-02-2022)“…Due to the developments in the treatment for hepatitis, it is possible to prevent the progression of liver fibrosis and improve patients' prognosis even if it…”
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16
Letrozole ameliorates liver fibrosis through the inhibition of the CTGF pathway and 17β-hydroxysteroid dehydrogenase 13 expression
Published in Journal of gastroenterology (2023)“…Background To establish a treatment option for liver fibrosis, the possibility of the drug repurposing theory was investigated, with a focus on the off-target…”
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17
Diagnosis and management of fibromuscular dysplasia and segmental arterial mediolysis in gastroenterology field: A mini-review
Published in World journal of gastroenterology : WJG (28-08-2018)“…The vascular diseases including aneurysm, occlusion, and thromboses in the mesenteric lesions could cause severe symptoms and appropriate diagnosis and…”
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18
Small Intestinal Bacterial Overgrowth Diagnosed by a Breath Test and Improved by Rifaximin in a Patient with Hepatic Encephalopathy and Alcoholic Liver Cirrhosis
Published in Internal Medicine (01-08-2020)“…A 66-year-old Japanese man was admitted to our hospital with grade 2 hepatic encephalopathy (HE). Abdominal computed tomography and laboratory examinations…”
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19
Modulation of serotonin in the gut-liver neural axis ameliorates the fatty and fibrotic changes in non-alcoholic fatty liver
Published in Disease models & mechanisms (28-03-2021)“…The etiology of non-alcoholic fatty liver disease (NAFLD) consists of various factors, including neural signal pathways. However, the molecular mechanisms of…”
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20
Correction: Modulation of serotonin in the gut-liver neural axis ameliorates the fatty and fibrotic changes in non-alcoholic fatty liver
Published in Disease models & mechanisms (01-12-2023)Get full text
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