Search Results - "Sakaki‐Yumoto, Masayo"
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Economic burden of alopecia areata: A study of direct and indirect cost in Japan using real-world data
Published in Journal of dermatology (01-10-2023)“…Alopecia area (AA) is a common autoimmune disorder, characterized by hair loss. Although its impact on quality of life is fairly well understood, studies on…”
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Umbilical cord derived mesenchymal stromal cells in microcarrier based industrial scale culture sustain the immune regulatory functions
Published in Biotechnology journal (01-06-2021)“…Mesenchymal stromal cells (MSCs) have been isolated from numerous sources and are potentially therapeutic against various diseases. Umbilical cord‐derived MSCs…”
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TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association
Published in Science signaling (01-05-2012)“…Ectodomain shedding mediated by tumor necrosis factor-α (TNF-α)-converting enzyme [TACE; also known as ADAM17 (a disintegrin and metalloproteinase 17)]…”
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Smad2 Is Essential for Maintenance of the Human and Mouse Primed Pluripotent Stem Cell State
Published in The Journal of biological chemistry (21-06-2013)“…Human embryonic stem cells and mouse epiblast stem cells represent a primed pluripotent stem cell state that requires TGF-β/activin signaling. TGF-β and/or…”
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The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development
Published in Development (Cambridge) (01-08-2006)“…Mutations in SALL4 , the human homolog of the Drosophila homeotic gene spalt ( sal ), cause the autosomal dominant disorder known as Okihiro syndrome. In this…”
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Degree of Alignment Between Japanese Patients and Physicians on Alopecia Areata Disease Severity and Treatment Satisfaction: A Real-World Survey
Published in Dermatology and therapy (01-01-2024)“…Introduction Alopecia areata (AA) is characterized by non-scarring scalp and/or body hair loss and can negatively impact patient mental health. Data are…”
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Effects of the dipeptide L-glutamic acid-L-tryptophan on dermatitis in mice and human keratinocytes
Published in Heliyon (01-01-2022)“…Allergic contact dermatitis (ACD) and atopic dermatitis (AD) are inflammatory eczematous skin diseases caused by various factors. Here, we report that topical…”
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TGF-β family signaling in stem cells
Published in Biochimica et biophysica acta (01-02-2013)“…The diversity of cell types and tissue types that originate throughout development derives from the differentiation potential of embryonic stem cells and…”
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Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-2016)“…Developmental signaling molecules are used for cell fate determination, and understanding how their combinatorial effects produce the variety of cell types in…”
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Study on the Umbilical Cord-Mesenchymal Stem Cell Manufacturing Using Clinical-Grade Culture Medium
Published in Tissue engineering. Part C, Methods (01-01-2022)“…Mesenchymal stem/stromal cell (MSC)-based therapies have been gaining increasing attention owing to their application in various diseases and conditions. In…”
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