Search Results - "Sakai, Ayumu"

A variant of the sigma receptor type-1 gene is a protective factor for Alzheimer disease by Uchida, Naohiko, Ujike, Hiroshi, Tanaka, Yuji, Sakai, Ayumu, Yamamoto, Mitsutoshi, Fujisawa, Yoshikatsu, Kanzaki, Akihiro, Kuroda, Shigetoshi

“…Some preclinical evidence suggests that the sigma receptor type 1, which plays several roles in learning and memory, may also be involved in the pathogenesis…”
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Reduced CYP2D6 activity is a negative risk factor for methamphetamine dependence by Otani, Kyohei, Ujike, Hiroshi, Sakai, Ayumu, Okahisa, Yuko, Kotaka, Tatsuya, Inada, Toshiya, Harano, Mutsuo, Komiyama, Tokutaro, Hori, Toru, Yamada, Mitsuhiko, Sekine, Yoshimoto, Iwata, Nakao, Iyo, Masaomi, Sora, Ichiro, Ozaki, Norio, Kuroda, Shigetoshi

“…Because methamphetamine (METH) is metabolized by CYP2D6 at the first step of hydroxylation and demethylation, it is possible that functional variants of CYP2D6…”
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No association between the sigma receptor type 1 gene and schizophrenia: results of analysis and meta-analysis of case-control studies by Uchida, Naohiko, Ujike, Hiroshi, Nakata, Kenji, Takaki, Manabu, Nomura, Akira, Katsu, Takeshi, Tanaka, Yuji, Imamura, Takaki, Sakai, Ayumu, Kuroda, Shigetoshi

“…Several lines of evidence have supported possible roles of the sigma receptors in the etiology of schizophrenia and mechanisms of antipsychotic efficacy. An…”
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High electrical performance of carbon nanotubes/rubber composites with low percolation threshold prepared with a rotation–revolution mixing technique by Tsuchiya, Koji, Sakai, Ayumu, Nagaoka, Tomoya, Uchida, Katsumi, Furukawa, Takeo, Yajima, Hirofumi

“…The present study demonstrates a novel mixing approach for achieving a good dispersion of carbon nanotubes (CNTs) in a styrene–butadiene rubber (SBR), which…”
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Association study of the brain-derived neurotrophic factor (BDNF) gene with bipolar disorder by Nakata, Kenji, Ujike, Hiroshi, Sakai, Ayumu, Uchida, Naohiko, Nomura, Akira, Imamura, Takaki, Katsu, Takeshi, Tanaka, Yuji, Hamamura, Takashi, Kuroda, Shigetoshi

“…Brain-derived neurotrophic factor (BDNF) belongs to a family of neurotrophic factors and has been demonstrated to promote the survival, differentiation, and…”
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The human dihydropyrimidinase-related protein 2 gene on chromosome 8p21 is associated with paranoid-type schizophrenia by Nakata, Kenji, Ujike, Hiroshi, Sakai, Ayumu, Takaki, Manabu, Imamura, Takaki, Tanaka, Yuji, Kuroda, Shigetoshi

“…The dihydropyrimidinase-related protein (DRP) family, also called the collapsin response mediator protein, is implicated in the developmental process of the…”
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The human frizzled-3 ( FZD3) gene on chromosome 8p21, a receptor gene for Wnt ligands, is associated with the susceptibility to schizophrenia by Katsu, Takeshi, Ujike, Hiroshi, Nakano, Takamitsu, Tanaka, Yuji, Nomura, Akira, Nakata, Kenji, Takaki, Manabu, Sakai, Ayumu, Uchida, Naohiko, Imamura, Takaki, Kuroda, Shigetoshi

“…Neurodevelopmental abnormalities have been reported in studies on the pathogenesis of schizophrenia. The Wnt-signaling pathway has been implicated in a variety…”
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A nonsynonymous polymorphism in the human fatty acid amide hydrolase gene did not associate with either methamphetamine dependence or schizophrenia by Morita, Yukitaka, Ujike, Hiroshi, Tanaka, Yuji, Uchida, Naohiko, Nomura, Akira, Ohtani, Kyohei, Kishimoto, Makiko, Morio, Akiko, Imamura, Takaki, Sakai, Ayumu, Inada, Toshiya, Harano, Mutsuo, Komiyama, Tokutaro, Yamada, Mitsuhiko, Sekine, Yoshimoto, Iwata, Nakao, Iyo, Masaomi, Sora, Ichiro, Ozaki, Norio, Kuroda, Shigetoshi

“…Genetic contributions to the etiology of substance abuse and dependence are topics of major interest. Acute and chronic cannabis use can produce drug-induced…”
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Association of the Neprilysin gene with susceptibility to late-onset Alzheimer's disease by Sakai, Ayumu, Ujike, Hiroshi, Nakata, Kenji, Takehisa, Yasushi, Imamura, Takaki, Uchida, Naohiko, Kanzaki, Akihiro, Yamamoto, Mitsutoshi, Fujisawa, Yoshikatsu, Okumura, Kazuya, Kuroda, Shigetoshi

“…Neprilysin (NEP), also known as neutral endopeptidase, enkephalinase, CD 10, and common acute lymphoblastic leukemia antigen, is a 97-kD protein. NEP can…”
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No association between the insulin degrading enzyme gene and Alzheimer's disease in a Japanese population by Sakai, Ayumu, Ujike, Hiroshi, Nakata, Kenji, Takehisa, Yasushi, Imamura, Takaki, Uchida, Naohiko, Kanzaki, Akihiro, Yamamoto, Mitsutoshi, Fujisawa, Yoshikatsu, Okumura, Kazuya, Kuroda, Shigetoshi

“…Susceptibility to Alzheimer's disease (AD) is thought to be regulated by multiple genetic factors. Recently, three independent studies have reported that loci…”
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Association study between the fibronectin gene and schizophrenia by Nakata, Kenji, Ujike, Hiroshi, Sakai, Ayumu, Takaki, Manabu, Imamura, Takaki, Tanaka, Yuji, Kuroda, Shigetoshi

“…Fibronectin is one of the cell adhesion proteins. Adhesion molecules play an important role in neural and synaptic genesis, and their dysfunction may result in…”
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Association study between cytochrome P450 2D6 genotype and patients with methamphetamine dependence by Otani, Kyohei, Ujike, Hiroshi, Sakai, Ayumu, Tanaka, Yuji, Uchida, Naohiko, Nomura, Akira, Morita, Yukitaka, Kishimoto, Makiko, Morio, Akiko, Inada, Toshiya, Harano, Mutsuo, Komiyama, Tokutaro, Hori, Toru, Yamada, Mitsuhiko, Sekine, Yoshimoto, Iwata, Nakao, Iyo, Masaomi, Sora, Ichiro, Ozaki, Norio, Kuroda, Shigetoshi

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No association between the dihydropyrimidinase-related protein 2 (DRP-2) gene and bipolar disorder in humans by Nakata, Kenji, Ujike, Hiroshi, Tanaka, Yuji, Takaki, Manabu, Sakai, Ayumu, Nomura, Akira, Katsu, Takeshi, Uchida, Naohiko, Imamura, Takaki, Fujiwara, Yutaka, Hamamura, Takashi, Kuroda, Shigetoshi

“…Several susceptibility loci for both of schizophrenia and bipolar disorder (BPD) have been found to overlap on several chromosomes including 8p21. Expression…”
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