Search Results - "Sakaguchi, N"

Germinal Center B-Cell-Associated Nuclear Protein (GANP) Involved in RNA Metabolism for B Cell Maturation by Sakaguchi, N, Maeda, K

“…Germinal center B-cell-associated nuclear protein (GANP) is upregulated in germinal center B cells against T-cell-dependent antigens in mice and humans. In…”
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Radiation-induced segregation and corrosion behavior on Σ3 coincidence site lattice and random grain boundaries in proton-irradiated type-316L austenitic stainless steel by Sakaguchi, N., Endo, M., Watanabe, S., Kinoshita, H., Yamashita, S., Kokawa, H.

“…The behavior of radiation-induced segregation (RIS) and intergranular corrosion at random grain boundaries and Σ3 coincidence site lattice (CSL) boundaries in…”
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Surface cracking on Σ3, Σ9 CSL and random grain boundaries in helium implanted 316L austenitic stainless steel by Sakaguchi, N., Ohguchi, Y., Shibayama, T., Watanabe, S., Kinoshita, H.

“…The relationship between surface cracking at grain boundaries and the grain boundary nature in helium implanted 316L austenitic stainless steel was…”
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Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state by Takahashi, T, Kuniyasu, Y, Toda, M, Sakaguchi, N, Itoh, M, Iwata, M, Shimizu, J, Sakaguchi, S

“…Elimination of CD25+ T cells, which constitute 5-10% of peripheral CD4+ T cells in normal naive mice, leads to spontaneous development of various autoimmune…”
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Role of catalase in monocytic differentiation of U937 cells by TPA: hydrogen peroxide as a second messenger by Yamamoto, T, Sakaguchi, N, Hachiya, M, Nakayama, F, Yamakawa, M, Akashi, M

“…Human promonocytic cell line U937 cells can be induced to differentiate into macrophages by treatment with 12- O -tetradecanoylphorbol-13-acetate (TPA). TPA…”
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Molecular Mechanism of Immunoglobulin V‐Region Diversification Regulated by Transcription and RNA Metabolism in Antigen‐Driven B Cells by Sakaguchi, N., Maeda, K., Kuwahara, K.

“…The immune system produces specific antibodies (Ab) against any antigens (Ag) of exogenous and endogenous origins with a diverse repertoire of V‐region…”
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Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway by ITO, K, OJI, Y, TAMAKI, H, SAKAGUCHI, N, SHIRAKATA, T, NISHIDA, S, KAWAKAMI, M, TSUBOI, A, OKA, Y, TSUJIMOTO, Y, SUGIYAMA, H, TATSUMI, N, SHIMIZU, S, KANAI, Y, NAKAZAWA, T, ASADA, M, JOMGEOW, T, AOYAGI, S, NAKANO, Y

“…The WT1 gene is overexpressed in human primary leukemia and a wide variety of solid cancers. The WT1 gene is alternatively spliced at two sites, yielding four…”
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Grain boundary engineering of austenitic steel PNC316 for use in nuclear reactors by Sekine, M., Sakaguchi, N., Endo, M., Kinoshita, H., Watanabe, S., Kokawa, H., Yamashita, S., Yano, Y., Kawai, M.

“…Austenitic stainless steel PNC316 was subjected to grain boundary engineering (GBE). It was found that the grain boundary engineered PNC316 (PNC316-GBEM) had a…”
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Amla (Emblica officinalis Gaertn.) extracts reduce oxidative stress in streptozotocin-induced diabetic rats by Rao, T P, Sakaguchi, N, Juneja, L R, Wada, E, Yokozawa, T

“…The antioxidant properties of amla extracts and their effects on the oxidative stress in streptozotocin-induced diabetes were examined in rats. Amla in the…”
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Increased T Cell Autoreactivity in the Absence of CD40-CD40 Ligand Interactions: A Role of CD40 in Regulatory T Cell Development by Kumanogoh, Atsushi, Wang, Xiaosong, Lee, Ihnsook, Watanabe, Chie, Kamanaka, Masahito, Shi, Wei, Yoshida, Kanji, Sato, Takehito, Habu, Sonoko, Itoh, Misako, Sakaguchi, Noriko, Sakaguchi, Shimon, Kikutani, Hitoshi

“…Mutations in the CD40 ligand (CD40L) gene lead to X-linked immunodeficiency with hyper-IgM, which is often associated with autoimmune diseases. To determine…”
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IL-1 Enhances T Cell-Dependent Antibody Production Through Induction of CD40 Ligand and OX40 on T Cells by Nakae, Susumu, Asano, Masahide, Horai, Reiko, Sakaguchi, Nobuo, Iwakura, Yoichiro

“…IL-1 is a proinflammatory cytokine that plays pleiotropic roles in host defense mechanisms. We investigated the role of IL-1 in the humoral immune response…”
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Sink effect of grain boundary on radiation-induced segregation in austenitic stainless steel by Watanabe, S., Takamatsu, Y., Sakaguchi, N., Takahashi, H.

“…We have investigated the orientation dependence of grain boundaries in radiation-induced segregation (RIS) in an austenitic stainless steel under irradiation…”
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Antioxidant, gallic acid, induces apoptosis in HL-60RG cells by Inoue, M, Suzuki, R, Koide, T, Sakaguchi, N, Ogihara, Y, Yabu, Y

“…Gallic acid, a naturally occurring plant phenol with antioxidative activity, was found to induce cell death in promyelocytic leukemia HL-60RG cells, although…”
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Fabrication of Nanoparticles by Electric Discharge Plasma in Liquid by Yatsu, S., Takahashi, H., Sasaki, H., Sakaguchi, N., Ohkubo, K., Muramoto, T., Watanabe, S.

“…The electric plasma discharge method involves the application of a voltage between a cathode and anode in a conductive electrolytic solution to create a…”
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Autoantibodies to NMDA receptor in patients with chronic forms of epilepsia partialis continua by TAKAHASHI, Y, MORI, H, NISHIDA, H, IMAI, K, SAKAGUCHI, N, KONDO, N, MISHINA, M, WATANABE, M, FUJIWARA, T, SHIMOMURA, J, AIBA, H, MIYAJIMA, T, SAITO, Y, NEZU, A

“…Antibody-mediated and cytotoxic T cell-mediated pathogenicity have been implicated as the autoimmune pathophysiologic mechanisms in Rasmussen's encephalitis…”
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Role of Reactive Oxygen Species in Gallic Acid-Induced Apoptosis by INOUE, Makoto, SAKAGUCHI, Nahoko, ISUZUGAWA, Kazuto, TANI, Hiroyuki, OGIHARA, Yukio

“…We earlier demonstrated that gallic acid (3, 4, 5-trihydroxybenzoic acid) induced apoptosis in promyelocytic leukemia HL-60RG cells, which was inhibited by…”
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Cell-permeable intrinsic cellular inhibitors of apoptosis protect and rescue intestinal epithelial cells from radiation-induced cell death by Matsuzaki-Horibuchi, Shiori, Yasuda, Takeshi, Sakaguchi, Nagako, Yamaguchi, Yoshihiro, Akashi, Makoto

“…One of the important mechanisms for gastrointestinal (GI) injury following high-dose radiation exposure is apoptosis of epithelial cells. X-linked inhibitor of…”
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Cytokine production profile of splenocytes derived from zymosan A-treated SKG mice developing arthritis by Kobayashi, K, Suda, T, Nan-Ya, K, Sakaguchi, N, Sakaguchi, S, Miki, I

“…SKG mice have a point mutation of the zeta-associated protein of 70 kD (ZAP-70) and spontaneously develop a severe polyarthritis in the conventional condition,…”
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Microstructural development in a model austenitic alloy following electron and ion irradiation by Sakaguchi, N., Kinoshita, H., Watanabe, S., Sueishi, Y., Akasaka, N., Takahashi, H.

“…In order to study the microstructural evolution of cascade and interaction between cascade and He, the irradiations were carried out using ion accelerator to…”
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Effect of hafnium on radiation-induced inter-granular segregation in ferritic steel by Lu, Z., Faulkner, R.G., Sakaguchi, N., Kinoshita, H., Takahashi, H., Flewitt, P.E.J.

“…Ferritic steels with and without hafnium (Hf) addition were irradiated by 250 keV nickel ions at 300 °C in an ion accelerator attached to the multi-beam high…”
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