Search Results - "Sajjan, S."

Identification of small molecules using accurate mass MS/MS search by Kind, Tobias, Tsugawa, Hiroshi, Cajka, Tomas, Ma, Yan, Lai, Zijuan, Mehta, Sajjan S., Wohlgemuth, Gert, Barupal, Dinesh Kumar, Showalter, Megan R., Arita, Masanori, Fiehn, Oliver

“…Tandem mass spectral library search (MS/MS) is the fastest way to correctly annotate MS/MS spectra from screening small molecules in fields such as…”
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Structure Annotation of All Mass Spectra in Untargeted Metabolomics by Blaženović, Ivana, Kind, Tobias, Sa, Michael R, Ji, Jian, Vaniya, Arpana, Wancewicz, Benjamin, Roberts, Bryan S, Torbašinović, Hrvoje, Lee, Tack, Mehta, Sajjan S, Showalter, Megan R, Song, Hosook, Kwok, Jessica, Jahn, Dieter, Kim, Jayoung, Fiehn, Oliver

“…Urine metabolites are used in many clinical and biomedical studies but usually only for a few classic compounds. Metabolomics detects vastly more metabolic…”
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Increasing Compound Identification Rates in Untargeted Lipidomics Research with Liquid Chromatography Drift Time–Ion Mobility Mass Spectrometry by Blaženović, Ivana, Shen, Tong, Mehta, Sajjan S, Kind, Tobias, Ji, Jian, Piparo, Marco, Cacciola, Francesco, Mondello, Luigi, Fiehn, Oliver

“…Unknown metabolites represent a bottleneck in untargeted metabolomics research. Ion mobility–mass spectrometry (IM-MS) facilitates lipid identification because…”
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The incidence of construction site injuries to women in Delhi: capture-recapture study by Yadav, Sajjan S, Edwards, Phil, Porter, John

“…In India, the construction sector provides the main alternative to agricultural work - seasonal migration to and from construction work is widespread and…”
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Quercetin prevents rhinovirus-induced progression of lung disease in mice with COPD phenotype by Farazuddin, Mohammad, Mishra, Rahul, Jing, Yaxun, Srivastava, Vikram, Comstock, Adam T, Sajjan, Umadevi S

“…Acute exacerbations are the major cause of morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD). Rhinovirus, which causes…”
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Neonatal rhinovirus induces mucous metaplasia and airways hyperresponsiveness through IL-25 and type 2 innate lymphoid cells by Hong, Jun Young, MS, Bentley, J. Kelley, PhD, Chung, Yutein, PhD, Lei, Jing, BS, Steenrod, Jessica M., BS, Chen, Qiang, BS, Sajjan, Uma S., PhD, Hershenson, Marc B., MD

“…Background Early-life human rhinovirus infection has been linked to asthma development in high-risk infants and children. Nevertheless, the role of rhinovirus…”
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Barrier function of airway tract epithelium by Ganesan, Shyamala, Comstock, Adam T, Sajjan, Uma S

“…Airway epithelium contributes significantly to the barrier function of airway tract. Mucociliary escalator, intercellular apical junctional complexes which…”
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Quercetin improves epithelial regeneration from airway basal cells of COPD patients by McCluskey, Elizabeth S, Liu, Nathan, Pandey, Abhimaneu, Marchetti, Nathaniel, Kelsen, Steven G, Sajjan, Umadevi S

“…Airway basal cells (BC) from patients with chronic obstructive pulmonary disease (COPD) regenerate abnormal airway epithelium and this was associated with…”
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Comprehensive comparison of in silico MS/MS fragmentation tools of the CASMI contest: database boosting is needed to achieve 93% accuracy by Blaženović, Ivana, Kind, Tobias, Torbašinović, Hrvoje, Obrenović, Slobodan, Mehta, Sajjan S., Tsugawa, Hiroshi, Wermuth, Tobias, Schauer, Nicolas, Jahn, Martina, Biedendieck, Rebekka, Jahn, Dieter, Fiehn, Oliver

“…In mass spectrometry-based untargeted metabolomics, rarely more than 30% of the compounds are identified. Without the true identity of these molecules it is…”
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Contribution of dipeptidyl peptidase 4 to non-typeable Haemophilus influenzae-induced lung inflammation in COPD by Kotnala, Sudhir, Kim, Yerin, Rajput, Charu, Reddyvari, Hymavathi, Bolla, Sudhir, Marchetti, Nathaniel T, Kosmider, Beata, Bahmed, Karim, Sajjan, Umadevi S

“…Dipeptidyl peptidase 4 (DPP4) expression is increased in the lungs of chronic obstructive pulmonary disease (COPD). DPP4 is known to be associated with…”
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Quercetin inhibits rhinovirus replication in vitro and in vivo by Ganesan, Shyamala, Faris, Andrea N., Comstock, Adam T., Wang, Qiong, Nanua, Suparna, Hershenson, Marc B., Sajjan, Uma S.

“…► Rhinovirus is responsible for majority of common colds. ► There are no FDA approved drugs are available to treat rhinovirus infection. ► We show that…”
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Aberrantly activated EGFR contributes to enhanced IL-8 expression in COPD airways epithelial cells via regulation of nuclear FoxO3A by Ganesan, Shyamala, Unger, Benjamin L, Comstock, Adam T, Angel, Kristen A, Mancuso, Peter, Martinez, Fernando J, Sajjan, Umadevi S

“…Decreased activity of forkhead transcription factor class O (FoxO)3A, a negative regulator of NF-κB-mediated chemokine expression, is implicated in the…”
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FOXO3a regulates rhinovirus-induced innate immune responses in airway epithelial cells by Gimenes-Junior, Joao, Owuar, Nicole, Vari, Hymavathi Reddy, Li, Wuyan, Xander, Nathaniel, Kotnala, Sudhir, Sajjan, Uma S.

“…Forkhead transcription factor class O (FOXO)3a, which plays a critical role in a wide variety of cellular processes, was also found to regulate…”
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Randomised clinical trial to determine the safety of quercetin supplementation in patients with chronic obstructive pulmonary disease by Han, Meilan K, Barreto, Tyler A, Martinez, Fernando J, Comstock, Adam T, Sajjan, Umadevi S

“…IntroductionQuercetin is a plant flavonoid and has potent antioxidant and anti-inflammatory properties. In a preclinical model of chronic obstructive pulmonary…”
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SPLASH, a hashed identifier for mass spectra by Wohlgemuth, Gert, Mehta, Sajjan S, Mejia, Ramon F, Neumann, Steffen, Pedrosa, Diego, Pluskal, Tomáš, Schymanski, Emma L, Willighagen, Egon L, Wilson, Michael, Wishart, David S, Arita, Masanori, Dorrestein, Pieter C, Bandeira, Nuno, Wang, Mingxun, Schulze, Tobias, Salek, Reza M, Steinbeck, Christoph, Nainala, Venkata Chandrasekhar, Mistrik, Robert, Nishioka, Takaaki, Fiehn, Oliver

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Nod-like receptor X-1 is required for rhinovirus-induced barrier dysfunction in airway epithelial cells by Unger, Benjamin L, Ganesan, Shyamala, Comstock, Adam T, Faris, Andrea N, Hershenson, Marc B, Sajjan, Uma S

“…Barrier dysfunction of airway epithelium may increase the risk for acquiring secondary infections or allergen sensitization. Both rhinovirus (RV) and…”
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MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness by Wang, Qiong, Miller, David J, Bowman, Emily R, Nagarkar, Deepti R, Schneider, Dina, Zhao, Ying, Linn, Marisa J, Goldsmith, Adam M, Bentley, J Kelley, Sajjan, Umadevi S, Hershenson, Marc B

“…Rhinovirus (RV), a single-stranded RNA picornavirus, is the most frequent cause of asthma exacerbations. We previously demonstrated in human bronchial…”
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Frequency of discontinuation of injectable osteoporosis therapies in US patients over 2 years by Modi, A., Sajjan, S., Insinga, R., Weaver, J., Lewiecki, E. M., Harris, S. T.

“…Summary Little is known about treatment patterns with injectable osteoporosis therapies. At 12 months, the probability of discontinuation was 69.1% among…”
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Rhinovirus-Induced Barrier Dysfunction in Polarized Airway Epithelial Cells Is Mediated by NADPH Oxidase 1 by COMSTOCK, Adam T, GANESAN, Shyamala, CHATTORAJ, Asamanja, FARIS, Andrea N, MARGOLIS, Benjamin L, HERSHENSON, Marc B, SAJJAN, Umadevi S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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TLR2 Activation Limits Rhinovirus-Stimulated CXCL-10 by Attenuating IRAK-1-Dependent IL-33 Receptor Signaling in Human Bronchial Epithelial Cells by Ganesan, Shyamala, Pham, Duc, Jing, Yaxun, Farazuddin, Mohammad, Hudy, Magdalena H, Unger, Benjamin, Comstock, Adam T, Proud, David, Lauring, Adam S, Sajjan, Uma S

“…Airway epithelial cells are the major target for rhinovirus (RV) infection and express proinflammatory chemokines and antiviral cytokines that play a role in…”
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