Search Results - "Saitoh, Shinichiroh"
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1
Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation
Published in Nature immunology (01-08-2002)“…Fc epsilon RI activation of mast cells is thought to involve Lyn and Syk kinases proximal to the receptor and the signaling complex organized by the linker for…”
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2
Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling
Published in Biochemical and biophysical research communications (28-03-2008)“…Toll-like receptor 4 (TLR4) activates two distinct signaling pathways inducing production of proinflammatory cytokines or type I interferons (IFNs),…”
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LAT Is Essential for FcεRI-Mediated Mast Cell Activation
Published in Immunity (Cambridge, Mass.) (01-05-2000)“…The linker molecule LAT is a substrate of the tyrosine kinases activated following TCR engagement of T cells. LAT is also expressed in platelets, NK, and mast…”
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