Search Results - "Saito, Tais B"
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Inhibition of caspase pathways limits CD4 + T cell loss and restores host anti-retroviral function in HIV-1 infected humanized mice with augmented lymphoid tissue
Published in Retrovirology (02-05-2024)“…The study of HIV infection and pathogenicity in physical reservoirs requires a biologically relevant model. The human immune system (HIS) mouse is an…”
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2
Endothelial Exosome Plays a Functional Role during Rickettsial Infection
Published in mBio (11-05-2021)“…Spotted fever group rickettsioses (SFRs) are devastating human infections. Vascular endothelial cells (ECs) are the primary targets of rickettsial infection…”
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3
Intravascular persistence of Anaplasma platys, Ehrlichia chaffeensis, and Ehrlichia ewingii DNA in the blood of a dog and two family members
Published in Parasites & vectors (01-07-2014)“…BACKGROUND: Anaplasmosis, caused by Anaplasma phagocytophilum and Anaplasma platys, and ehrlichiosis, caused by Ehrlichia chaffeensis, Ehrlichia ewingii, the…”
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4
Distinct virulence of Rift Valley fever phlebovirus strains from different genetic lineages in a mouse model
Published in PloS one (21-12-2017)“…Rift Valley fever phlebovirus (RVFV) causes high rates of abortions and fetal malformations in ruminants, and hemorrhagic fever, encephalitis, or blindness in…”
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5
Ehrlichioses: An Important One Health Opportunity
Published in Veterinary sciences (31-08-2016)“…Ehrlichioses are caused by obligately intracellular bacteria that are maintained subclinically in a persistently infected vertebrate host and a tick vector…”
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Small Animal Model of Post-chemotherapy Tuberculosis Relapse in the Setting of HIV Co-infection
Published in Frontiers in cellular and infection microbiology (16-04-2020)“…Tuberculosis relapse following drug treatment of active disease is an important global public health problem due to the poorer clinical outcomes and increased…”
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7
Self-adjuvanting nanovaccines boost lung-resident CD4+ T cell immune responses in BCG-primed mice
Published in npj vaccines (26-04-2022)“…Heterologous vaccine regimens could extend waning protection in the global population immunized with Mycobacterium bovis Bacille Calmette-Guerin (BCG). We…”
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Canine Infection by Rickettsiae and Ehrlichiae in Southern Brazil
Published in The American journal of tropical medicine and hygiene (01-07-2008)“…This study evaluated the infection caused by Rickettsia and Ehrlichia agents among dogs in southern Brazil. A total of 389 dogs were tested by the indirect…”
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Host EPAC1 Modulates Rickettsial Adhesion to Vascular Endothelial Cells via Regulation of ANXA2 Y23 Phosphorylation
Published in Pathogens (Basel) (12-10-2021)“…Intracellular cAMP receptor exchange proteins directly activated by cAMP 1 ( ) regulate obligate intracellular parasitic bacterium rickettsial adherence to and…”
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10
Experimental infection of dogs with a Brazilian strain of Rickettsia rickettsii: clinical and laboratory findings
Published in Memórias do Instituto Oswaldo Cruz (01-11-2008)“…The bacterium Rickettsia rickettsii is the etiological agent of an acute, severe disease called Rocky Mountain spotted fever in the United States or Brazilian…”
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Amblyomma imitator ticks as vectors of Rickettsia rickettsii, Mexico
Published in Emerging infectious diseases (01-08-2010)“…Real-time PCR of Amblyomma imitator tick egg masses obtained in Nuevo Leon State, Mexico, identified a Rickettsia species. Sequence analyses of 17-kD common…”
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12
Immunization with Ehrlichia P28 Outer Membrane Proteins Confers Protection in a Mouse Model of Ehrlichiosis
Published in Clinical and Vaccine Immunology (01-12-2011)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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13
Vector Tick Transmission Model of Spotted Fever Rickettsiosis
Published in The American journal of pathology (01-01-2019)“…Many aspects of rickettsial infections have been characterized, including pathogenic and immune pathways and mechanisms of rickettsial survival within the…”
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14
Identification of common sequence motifs shared exclusively among selectively packed exosomal pathogenic microRNAs during rickettsial infections
Published in Journal of cellular physiology (01-08-2023)“…We previously reported that microRNA (miR)23a and miR30b are selectively sorted into exosomes derived from rickettsia‐infected endothelial cells (R‐ECExos)…”
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Novel Role for Macrophage Galactose-Type Lectin-1 to Regulate Innate Immunity against Mycobacterium tuberculosis
Published in The Journal of immunology (1950) (01-07-2021)“…Tuberculosis (TB) caused by infection with is characterized by inflammatory pathology and poorly understood mechanisms of innate immunity. Pattern recognition…”
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Intracellular receptor EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K-/eNOS-dependent manner during inflammation
Published in The Journal of biological chemistry (01-11-2021)“…Coagulopathy is associated with both inflammation and infection, including infections with novel severe acute respiratory syndrome coronavirus-2, the causative…”
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Effect of high-fat diet on peripheral blood mononuclear cells and adipose tissue in early stages of diet-induced weight gain
Published in British journal of nutrition (28-12-2019)“…Subcutaneous adipose tissue (scAT) and peripheral blood mononuclear cells (PBMC) play a significant role in obesity-associated systemic low-grade inflammation…”
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Contribution of Human Lung Parenchyma and Leukocyte Influx to Oxidative Stress and Immune System-Mediated Pathology following Nipah Virus Infection
Published in Journal of virology (01-08-2017)“…Nipah virus (NiV) is a zoonotic emerging paramyxovirus that can cause fatal respiratory illness or encephalitis in humans. Despite many efforts, the molecular…”
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A Hematogenously Disseminated Orientia tsutsugamsushi-Infected Murine Model of Scrub Typhus
Published in PLoS neglected tropical diseases (01-07-2014)“…Orientia tsutsugamushi, the etiologic agent of scrub typhus, is a mite-borne rickettsia transmitted by the parasitic larval stage of trombiculid mites…”
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Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis
Published in Vaccine (05-12-2013)“…Highlights • Immunization with recombinant E. muris P29 induced protective immune responses. • Protection induced by rP29 was associated with development of…”
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