Search Results - "Saito, Kosuke"

Application of comprehensive lipidomics to biomarker research on adverse drug reactions by Saito, Kosuke

“…Lipidomics is a relatively new field of omics that focuses on lipids, one of the major categories of metabolites. Owing to their various functions, lipids are…”
Get full text

Correlation between Membrane Permeability and the Intracellular Degradation Activity of Proteolysis-Targeting Chimeras by Yokoo, Hidetomo, Osawa, Hinata, Saito, Kosuke, Demizu, Yosuke

“…Proteolysis-targeting chimeras (PROTACs) have attracted attention as an innovative drug modality that induces the selective degradation of target proteins…”
Get full text

Marimo nanocarbons composed of a cup-stacked carbon nanofilaments as anode catalyst support for enhanced power performance of direct methanol fuel cells by Saito, Kosuke, Shibata, Akihiro, Nakagawa, Kiyoharu

“…Marimo nanocarbon(MNC) derived from C2 H4 and C3H6 contain many carbon nanofilaments (CNFs) with small filament diameters, whereas C2H6 and C3H8 contain many…”
Get full text

Direct Growth of Graphene Films on Sapphire (0001) and (112̅0) Surfaces by Self-Catalytic Chemical Vapor Deposition by Saito, Kosuke, Ogino, Toshio

“…We investigated mechanism of the metal-catalyst-free direct growth of graphene films in chemical vapor deposition on sapphire surfaces using three kinds of…”
Get full text

Characterization of volatile compounds in males of the skipper butterfly Daimio tethys (Lepidoptera: Hesperiidae) by Saito, Kosuke, Ohta, Shinji, Ômura, Hisashi

“…Butterflies in the family Hesperiidae are characterized by male-specific structures referred to as scent organs. The volatiles released from the male scent…”
Get full text

Plasma and serum lipidomics of healthy white adults shows characteristic profiles by subjects' gender and age by Ishikawa, Masaki, Maekawa, Keiko, Saito, Kosuke, Senoo, Yuya, Urata, Masayo, Murayama, Mayumi, Tajima, Yoko, Kumagai, Yuji, Saito, Yoshiro

“…Blood is a commonly used biofluid for biomarker discovery. Although blood lipid metabolites are considered to be potential biomarker candidates, their…”
Get full text

Lipidomic Signatures and Associated Transcriptomic Profiles of Clear Cell Renal Cell Carcinoma by Saito, Kosuke, Arai, Eri, Maekawa, Keiko, Ishikawa, Masaki, Fujimoto, Hiroyuki, Taguchi, Ryo, Matsumoto, Kenji, Kanai, Yae, Saito, Yoshiro

“…Renal cell carcinoma (RCC) is the most common histological type of adult kidney cancer. In this study, we obtained lipidomic profiles of clear cell RCC…”
Get full text

Lipidomic Analysis of Extracellular Vesicles Isolated from Human Plasma and Serum by Sun, Yuchen, Saito, Kosuke, Saito, Yoshiro

“…Lipidomics is an omics approach to comprehensively study lipid profiles in biological samples, such as plasma, serum, urine, and tissue specimens. Moreover,…”
Get more information

Lipid Profile Characterization and Lipoprotein Comparison of Extracellular Vesicles from Human Plasma and Serum by Sun, Yuchen, Saito, Kosuke, Saito, Yoshiro

“…Extracellular vesicles (EVs) consist of lipid bilayers, occur in various biofluids, and are invaluable in biomarker screening. Liquid chromatography coupled…”
Get full text

Hemoglobin in the blood acts as a chemosensory signal via the mouse vomeronasal system by Osakada, Takuya, Abe, Takayuki, Itakura, Takumi, Mori, Hiromi, Ishii, Kentaro K., Eguchi, Ryo, Murata, Ken, Saito, Kosuke, Haga-Yamanaka, Sachiko, Kimoto, Hiroko, Yoshihara, Yoshihiro, Miyamichi, Kazunari, Touhara, Kazushige

“…The vomeronasal system plays an essential role in sensing various environmental chemical cues. Here we show that mice exposed to blood and, consequently,…”
Get full text

Effects of serial cervical or tail blood sampling on toxicity and toxicokinetic evaluation in rats by Hattori, Norimichi, Takumi, Asuka, Saito, Kosuke, Saito, Yoshiro

“…To assess the influences of blood sampling volumes or sites on toxicological and toxicokinetic (TK) evaluations, 4-week duration animal studies and a…”
Get full text

Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver by Hori, Takeshi, Saito, Kosuke, Moore, Rick, Flake, Gordon P, Negishi, Masahiko

“…Phenobarbital, a nongenotoxic hepatocarcinogen, induces hepatic proliferation and promotes development of hepatocellular carcinoma (HCC) in rodents. Nuclear…”
Get full text

Establishment and characterization of a new conditionally immortalized human astrocyte cell line by Furihata, Tomomi, Ito, Ryo, Kamiichi, Atsuko, Saito, Kosuke, Chiba, Kan

“…Astrocytes are the most abundant cell types in mammalian brains, within which they participate in various neuronal activities, partly by utilizing the numerous…”
Get full text

Effect of microsampling (50 μL) on toxicological evaluation of methapyrilene, a hepatotoxic substance, in a collaborative 28-day study in female rats by Hattori, Norimichi, Yokoyama, Hideaki, Takumi, Asuka, Kawaguchi, Sayaka, Yamaguchi, Koki, Shimazaki, Taishi, Shibui, Yusuke, Saito, Kosuke, Saito, Yoshiro

“…Although microsampling of blood is recommended to promote the 3Rs in toxicokinetic (TK) evaluation, there are few reports applying microsampling in actual…”
Get full text

Enrichment of resolving power improves ion-peak quantification on a lipidomics platform by Saito, Kosuke, Ohno, Yasuo, Saito, Yoshiro

“…In this study, we delineated the importance of MS resolving power on the ion-peak quantification of lipids using an Orbitrap Fusion instrument and established…”
Get full text

Characterization of serotonin as a candidate biomarker of severity and prognosis of COVID-19 using LC/MS analysis by Saito, Kosuke, Ishikawa, Rika, Kitamura, Isao, Ogawa, Kumiko, Arakawa, Noriaki, Sun, Yuchen, Imai, Kazuo, Maeda, Takuya, Saito, Yoshiro, Hasegawa, Chihiro

“…The coronavirus disease 2019 (COVID-19) pandemic has been associated with high mortality worldwide. Owing to its complicated pathophysiology, diagnostic and…”
Get full text

In vivo study on the repair of rat Achilles tendon injury treated with non-thermal atmospheric-pressure helium microplasma jet by Nakazawa, Katusmasa, Toyoda, Hiromitsu, Manaka, Tomoya, Orita, Kumi, Hirakawa, Yoshihiro, Saito, Kosuke, Iio, Ryosuke, Shimatani, Akiyoshi, Ban, Yoshitaka, Yao, Hana, Otsuki, Ryosuke, Torii, Yamato, Oh, Jun-Seok, Shirafuji, Tatsuru, Nakamura, Hiroaki

“…Non-thermal atmospheric-pressure plasma (NTAPP) has been widely studied for clinical applications, e.g., disinfection, wound healing, cancer therapy,…”
Get full text

Fracture healing on non-union fracture model promoted by non-thermal atmospheric-pressure plasma by Saito, Kosuke, Toyoda, Hiromitsu, Okada, Mitsuhiro, Oh, Jun-Seok, Nakazawa, Katsumasa, Ban, Yoshitaka, Orita, Kumi, Shimatani, Akiyoshi, Yao, Hana, Shirafuji, Tatsuru, Nakamura, Hiroaki

“…Non-thermal atmospheric-pressure plasma (NTAPP) is attracting widespread interest for use in medical applications. The tissue repair capacity of NTAPP has been…”
Get full text

Gender- and Age-Associated Differences in Serum Metabolite Profiles among Japanese Populations by Saito, Kosuke, Maekawa, Keiko, Kinchen, Jason M., Tanaka, Rieko, Kumagai, Yuji, Saito, Yoshiro

“…Serum metabolites can reflect the diffusion/export of biochemicals from various organs. They can serve as biomarkers related to diseases and therapeutic…”
Get full text

Fluorescein Angiography for Monitoring Neural Blood Flow in Chronic Nerve Compression Neuropathy: Experimental Animal Models and Preliminary Clinical Observations by Saito, Kosuke, Okada, Mitsuhiro, Yokoi, Takuya, Hama, Shunpei, Nakamura, Hiroaki

“…Pathologies associated with neural blood disturbance have been reported in patients with chronic nerve compression (CNC) neuropathy. Fluorescein angiography…”
Get full text