Search Results - "Sait, Sheila N.J."

Deletion and deletion/insertion mutations in the juxtamembrane domain of the FLT3 gene in adult acute myeloid leukemia by Deeb, Kristin K, Smonskey, Matthew T, DeFedericis, HanChun, Deeb, George, Sait, Sheila N.J, Wetzler, Meir, Wang, Eunice S, Starostik, Petr

“…Abstract In contrast to FLT3 ITD mutations, in-frame deletions in the FLT3 gene have rarely been described in adult acute leukemia. We report two cases of AML…”
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Acute Myeloid Leukemia Secondary to Oxaliplatin Treatment for Esophageal Cancer by Damodaran, Senthilkumar, Bellavia, Tanya, Sait, Sheila N.J, Wang, Eunice S, Wetzler, Meir, Khushalani, Nikhil I

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Hypoxia-inducible factor-1α protein expression is associated with poor survival in normal karyotype adult acute myeloid leukemia by Deeb, George, Vaughan, Mary M, McInnis, Ian, Ford, Laurie Ann, Sait, Sheila N.J, Starostik, Petr, Wetzler, Meir, Mashtare, Terry, Wang, Eunice S

“…Abstract We examined the predictive impact of HIF-1α protein expression on clinical outcome of 84 normal karyotype acute myeloid leukemia (NK-AML) patients…”
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Myeloid blastic transformation of myeloproliferative neoplasms—A review of 112 cases by Noor, Syed J, Tan, Wei, Wilding, Gregory E, Ford, Laurie A, Barcos, Maurice, Sait, Sheila N.J, Block, AnneMarie W, Thompson, James E, Wang, Eunice S, Wetzler, Meir

“…Abstract Blastic transformation of myeloproliferative neoplasms (MPN) is still poorly understood. We describe a cohort of 23 Roswell Park Cancer Institute…”
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Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex by Clay-Gilmour, Alyssa I., Hahn, Theresa, Preus, Leah M., Onel, Kenan, Skol, Andrew, Hungate, Eric, Zhu, Qianqian, Haiman, Christopher A., Stram, Daniel O., Pooler, Loreall, Sheng, Xin, Yan, Li, Liu, Qian, Hu, Qiang, Liu, Song, Battaglia, Sebastiano, Zhu, Xiaochun, Block, AnneMarie W., Sait, Sheila N.J., Karaesmen, Ezgi, Rizvi, Abbas, Weisdorf, Daniel J., Ambrosone, Christine B., Tritchler, David, Ellinghaus, Eva, Ellinghaus, David, Stanulla, Martin, Clavel, Jacqueline, Orsi, Laurent, Spellman, Stephen, Pasquini, Marcelo C., McCarthy, Philip L., Sucheston-Campbell, Lara E.

“…The incidence and mortality rates of B-cell acute lymphoblastic leukemia (B-ALL) differ by age and sex. To determine if inherited genetic susceptibility…”
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Metachronous and synchronous presentation of acute myeloid leukemia and lung cancer by Varadarajan, Ramya, Ford, LaurieAnn, Sait, Sheila N.J, Block, AnneMarie W, Barcos, Maurice, Wallace, Paul K, Ramnath, Nithya, Wang, Eunice S, Wetzler, Meir

“…Abstract Smoking is associated with both acute myeloid leukemia (AML) and lung cancer. We therefore searched our database for concomitant presentation of AML…”
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Co-Expression of Urokinase With Haptoglobin in Human Carcinomas by Harvey, Shashikumar, Ph.D, Kohga, Shin, M.D, Sait, Sheila N.J., Ph.D, Markus, Gabor, Ph.D, Hurd, Thelma C., M.D, Martinick, Maisie, B.S, Geradts, Joseph, M.D, Saxena, Rakhee, M.D, Gibbs, John F., M.D

“…Background We have shown that colon and breast cancer contains large amounts of urokinase (uPA), and that these cells are the actual sites of its synthesis. We…”
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Acute myeloid leukemia and myelodysplastic syndrome following breast cancer: Increased frequency of other cancers and of cancers in multiple family members by Padmanabhan, Aruna, Baker, Julie A, Zirpoli, Gary, Sait, Sheila N.J, Ford, Laurie A, Moysich, Kirsten B, Baer, Maria R

“…Abstract Adjuvant chemotherapy and radiation therapy for breast cancer are associated with therapy-related acute myeloid leukemia (AML)/myelodysplastic…”
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Chronic myeloid leukemia after treatment of lymphoid malignancies: Response to imatinib mesylate and favorable outcomes in three patients by Ramanarayanan, Jeyanthi, Dunford, Lauren M., Baer, Maria R., Sait, Sheila N.J., Lawrence, William, McCarthy, Philip L.

“…Recent improved treatments for lymphoid malignancies produce more long-term survivors, yet increase the risk for secondary malignancies. Therapy-related…”
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Double minute chromosomes in acute myeloid leukemia and myelodysplastic syndrome: Identification of new amplification regions by fluorescence in situ hybridization and spectral karyotyping by Sait, Sheila N.J., Qadir, Misbah U., Conroy, Jeffrey M., Matsui, Sei-Ichi, Nowak, Norma J., Baer, Maria R.

“…Double minute chromosomes (dmin) are small chromatin bodies consisting of genes amplified in an extrachromosomal location. dmins are uncommon in hematologic…”
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Recurrent deletion of 9q34 in adult normal karyotype precursor B-cell acute lymphoblastic leukemia by Nowak, Norma J, Sait, Sheila N.J, Zeidan, Amer, Deeb, George, Gaile, Dan, Liu, Song, Ford, LaurieAnn, Wallace, Paul K, Wang, Eunice S, Wetzler, Meir

“…Abstract The prognosis of adult normal karyotype (NK) precursor B-cell acute lymphoblastic leukemia (B-ALL) has not improved over the last decade, mainly…”
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Demonstration of Urokinase Expression in Cancer Cells of Colon Adenocarcinomas by Immunohistochemistry and in Situ Hybridization by Harvey, Shashikumar R., Sait, Sheila N.J., Xu, Yan, Bailey, Joyce L., Penetrante, Remedios M., Markus, Gabor

“…The question whether urokinase is expressed in human colon cancer by the cancer cells themselves or by surrounding stromal elements such as fibroblasts,…”
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Truncated STAT proteins are prevalent at relapse of acute myeloid leukemia by Xia, Zheng, Sait, Sheila N.J, Baer, Maria R, Barcos, Maurice, Donohue, Kathleen A, Lawrence, David, Ford, Laurie Ann, Block, Anne Marie W, Baumann, Heinz, Wetzler, Meir

“…Signal transducer and activator of transcription (STAT) proteins are implicated in the control of cell survival, proliferation and differentiation in response…”
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Acute myeloid leukemia developing during imatinib mesylate therapy for chronic myeloid leukemia in the absence of new cytogenetic abnormalities by Pawarode, Attaphol, Sait, Sheila N.J, Nganga, Alain, Coignet, Lionel J, Barcos, Maurice, Baer, Maria R

“…Abstract The BCR/ABL tyrosine kinase inhibitor imatinib mesylate produces a high rate of cytogenetic responses in patients with Philadelphia (Ph)-positive…”
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Disease Progression on Ibrutinib Therapy Is Associated with a Poor Clinical Outcome in Chronic Lymphocytic Leukemia (CLL) Patients Managed in Standard Clinical Practice by Akhtar, Othman S., Torka, Pallawi, Bhat, Seema A., Hare, Ryan, Sait, Sheila N.J., Block, AnneMarie W., Hernandez-Ilizaliturri, Francisco J.

“…Introduction: Ibrutinib is an irreversible Bruton Tyrosine Kinase (BTK) inhibitor that has shown efficacy in the treatment of CLL as a front-line therapy or in…”
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Structure and Chromosomal Localization of the Human Salivary Mucin Gene, MUC7 by Bobek, Libuse A., Liu, Jianhua, Sait, Sheila N.J., Shows, Thomas B., Bobek, Yvonne A., Levine, Michael J.

“…We have isolated and characterized several MUC7 genomic clones encoding the human low-molecular-weight salivary mucin, MG2. The MUC7 gene spans ∼10.0 kb and…”
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Inhibition of LSD1 in Myelodysplastic Syndrome Progenitors Restores Differentiation of CD141Hi Conventional Dendritic Cells by Srivastava, Pragya, Tzetzo, Stephanie, Cortes Gomez, Eduardo, Eng, Kevin, Singh, Prashant K, De Jong, Kitty, Sait, Sheila N.J., Wiatrowski, Kyle, Lynch, Miranda L, Peresie, Jennifer, Wang, Jianmin, Griffiths, Elizabeth A., Nemeth, Michael J.

“…Background: Immunotherapeutic approaches for myelodysplastic syndrome (MDS) show promise, but progress is limited by our incomplete understanding of the…”
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Ofatumumab plus HyperCVAD/HD‐MA induction leads to high rates of minimal residual disease negativity in patients with newly diagnosed mantle cell lymphoma: Results of a phase 2 study by Torka, Pallawi, Akhtar, Othman S., Reddy, Nishitha M., Baysal, Bora E., Kader, Angela, Groman, Adrienne, Nichols, Jenna, Mavis, Cory, Tario, Joseph D., Block, AnneMarie W., Sait, Sheila N. J., Ghione, Paola, Sundaram, Suchitra, Przespolewski, Eugene R., Mohr, Alice, Lund, Ian, Kostrewa, Jessica, McWhite, Kenneth, DeMarco, Joseph, Johnson, Michael, Darrall, Andrea, Thomas‐Talley, Rosh‐Neke, Wallace, Paul K., Neppalli, Vishala, Hutson, Alan, Hernandez‐Ilizaliturri, Francisco J.

“…Background Ofatumumab is a humanized type 1 anti‐CD20 monoclonal antibody. Preclinical studies show improved complement‐mediated cytotoxicity (CMC) compared to…”
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Low 25(OH) vitamin D3 levels are associated with adverse outcome in newly diagnosed, intensively treated adult acute myeloid leukemia by Lee, Hun Ju, Muindi, Josephia R., Tan, Wei, Hu, Qiang, Wang, Dan, Liu, Song, Wilding, Gregory E., Ford, Laurie A., Sait, Sheila N. J., Block, Annemarie W., Adjei, Araba A., Barcos, Maurice, Griffiths, Elizabeth A., Thompson, James E, Wang, Eunice S., Johnson, Candace S., Trump, Donald L., Wetzler, Meir

“…BACKGROUND Several studies have suggested that low 25(OH) vitamin D3 levels may be prognostic in some malignancies, but no studies have evaluated their impact…”
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Ofatumumab Plus Hypercvad/MA Induction Leads to High Rates of Minimal Residual Disease (MRD) Negativity in Patients with Newly Diagnosed Mantle Cell Lymphoma, Results of a Phase 2 Study by Torka, Pallawi, Reddy, Nishitha, Groman, Adrienne, Kader, Angela, Nichols, Jenna, Hutson, Alan, Mavis, Cory, Tario, Joseph Dennis, Wallace, Paul K., Block, AnneMarie W., Sait, Sheila N.J., Baysal, Bora E, Neppalli, Vishala T., Sundaram, Suchitra, Hernandez-Ilizaliturri, Francisco J.

“…Background: Minimal residual disease (MRD) status is an independent prognostic marker for response duration in patients with mantle cell lymphoma (MCL)…”
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