Search Results - "Sait, Sheila Jani"

Inhibition of LSD1 in MDS progenitors restores differentiation of CD141Hi conventional dendritic cells by Srivastava, Pragya, Tzetzo, Stephanie L., Gomez, Eduardo Cortes, Eng, Kevin H., Jani Sait, Sheila N., Kuechle, Joseph B., Singh, Prashant K., De Jong, Kitty, Wiatrowski, Kyle R., Peresie, Jennifer, Dimitroff, Ava, Lynch, Miranda L., Wang, Jianmin, Abrams, Scott I., Griffiths, Elizabeth A., Nemeth, Michael J.

“…The use of immunotherapy to treat patients with myelodysplastic syndromes (MDS) shows promise but is limited by our incomplete understanding of the immunologic…”
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Concomitant Venetoclax and Imatinib for Comanaging Chronic Lymphocytic Leukemia and Chronic Myeloid Leukemia: A Case Report by Przespolewski, Eugene R, Baron, Jeffrey, Kashef, Farshid, Fu, Kai, Jani Sait, Sheila N, Hernandez-Ilizaliturri, Francisco, Thompson, James

“…Patients with synchronous malignancies can be problematic to diagnose and manage because workup and therapeutic targeting for each individual malignancy must…”
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Unusual B-Lymphoid Blastic Crisis as Initial Presentation of Chronic Myeloid Leukemia Imposes Diagnostic Challenges by Momen, Nouran, Baysal, Bora, Jani Sait, Sheila, Tario, Joseph, Qian, You-Wen

“…Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder, characterized by reciprocal translocation t(9,22) (q34; q11), leading to increased…”
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Genomic profiling of myeloid sarcoma by array comparative genomic hybridization by Deeb, George, Baer, Maria R., Gaile, Daniel P., Sait, Sheila N. Jani, Barcos, Maurice, Wetzler, Meir, Conroy, Jeffrey M., Nowak, Norma J., Cowell, John K., Cheney, Richard T.

“…Myeloid sarcoma (MS) is a tumor mass of myeloblasts or immature myeloid cells occurring in an extramedullary site. In this study, seven cases of MS [stomach…”
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The t(14;21)(q11.2;q22) Chromosomal Translocation Associated with T-Cell Acute Lymphoblastic Leukemia Activates the BHLHB1 Gene by Wang, Junjie, Jani-Sait, Sheila N., Escalon, Enrique A., Carroll, Andrew J., de Jong, Pieter J., Kirsch, Ilan R., Aplan, Peter D.

“…We have cloned the genomic breakpoints for a balanced t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia…”
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Insertion of MLL sequences into chromosome band 5q31 results in an MLL-AF5Q31 fusion and is a rare but recurrent abnormality associated with infant leukemia by Deveney, Ramona, Chervinsky, David S., Jani-Sait, Sheila N., Grossi, Mauro, Aplan, Peter D.

“…MLL gene rearrangements leading to production of MLL fusion proteins are commonly detected in infant leukemia patients; the most common MLL fusion associated…”
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NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia by RAZA-EGILMEZ, S. Z, JANI-SAIT, S. N, GROSSI, M, HIGGINS, M. J, SHOWS, T. B, APLAN, P. D

“…A novel chromosomal translocation, t(2;11)(q31;p15), was identified in a patient with therapy-related acute myelogenous leukemia (t-AML). Fluorescence in situ…”
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Rhabdomyosarcoma of the cervix in sisters with review of the literature by Villella, Jeannine A, Bogner, Paul N, Jani-Sait, Sheila N, Block, Anne Marie W, Lele, Shashikant

“…Pediatric embryonal heterologous rhabdomyosarcoma of the cervix is a rare tumor. We present an interesting clinico-pathologic situation of two sisters…”
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Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer by Alam, Aftab, Levanduski, Eric, Denz, Parker, Villavicencio, Helena Solleiro, Bhatta, Maulasri, Alhorebi, Lamees, Zhang, Yali, Gomez, Eduardo Cortes, Morreale, Brian, Senchanthisai, Sharon, Li, Jun, Turowski, Steven G., Sexton, Sandra, Sait, Sheila Jani, Singh, Prashant K., Wang, Jianmin, Maitra, Anirban, Kalinski, Pawel, DePinho, Ronald A., Wang, Huamin, Liao, Wenting, Abrams, Scott I., Segal, Brahm H., Dey, Prasenjit

“…TH2 cells and innate lymphoid cells 2 (ILC2) can stimulate tumor growth by secreting pro-tumorigenic cytokines such as interleukin-4 (IL-4), IL-5, and IL-13…”
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Mechanisms of MLL gene rearrangement: site-specific DNA cleavage within the breakpoint cluster region is independent of chromosomal context by STANULLA, Martin, CHHALLIYIL, Pradheepkumar, JUNJIE WANG, JANI-SAIT, Sheila N, APLAN, Peter D

“…The MLL gene at chromosome band 11q23 is specifically cleaved at a unique site within its breakpoint cluster region (bcr) during the higher order chromatin…”
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Inhibition of LSD1 in MDS progenitors restores differentiation of CD141.sup.Hi conventional dendritic cells by Srivastava, Pragya, Tzetzo, Stephanie L, Gomez, Eduardo Cortes, Eng, Kevin H, Jani Sait, Sheila N, Kuechle, Joseph B, Singh, Prashant K

“…The use of immunotherapy to treat patients with myelodysplastic syndromes (MDS) shows promise but is limited by our incomplete understanding of the immunologic…”
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Acute myeloid leukemia with LRRFIP1::FGFR1 rearrangement and a complex karyotype by Qian, You-Wen, Wang, Eunice S, Sait, Sheila Jani, Glenn, Sean T

“…We report a case of a 20-year-old man who presented with splenomegaly, hyperleukocytosis, anemia, and thrombocytopenia. A diagnosis of acute myeloid leukemia…”
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Ofatumumab plus HyperCVAD/HD‐MA induction leads to high rates of minimal residual disease negativity in patients with newly diagnosed mantle cell lymphoma: Results of a phase 2 study by Torka, Pallawi, Akhtar, Othman S., Reddy, Nishitha M., Baysal, Bora E., Kader, Angela, Groman, Adrienne, Nichols, Jenna, Mavis, Cory, Tario, Joseph D., Block, AnneMarie W., Sait, Sheila N. J., Ghione, Paola, Sundaram, Suchitra, Przespolewski, Eugene R., Mohr, Alice, Lund, Ian, Kostrewa, Jessica, McWhite, Kenneth, DeMarco, Joseph, Johnson, Michael, Darrall, Andrea, Thomas‐Talley, Rosh‐Neke, Wallace, Paul K., Neppalli, Vishala, Hutson, Alan, Hernandez‐Ilizaliturri, Francisco J.

“…Background Ofatumumab is a humanized type 1 anti‐CD20 monoclonal antibody. Preclinical studies show improved complement‐mediated cytotoxicity (CMC) compared to…”
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Abstract 2119: KRAS and fungi cooperate to drive IL33 secretion and type 2 immunity in the pancreatic cancer tumor microenvironment by Alam, Aftab, Levanduski, Eric, Bhatta, Maulasri, Senchanthisai, Sharon, Sait, Sheila Jani, Wang, Jianmin, Abrams, Scott I. Abrams I., Dey, Prasenjit

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, the five-year survival rate of PDAC patient is around ten percent. It is…”
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Carfilzomib combined with rituximab, ifosfamide, carboplatin, and etoposide for relapsed or refractory DLBCL by Torka, Pallawi, Groman, Adrienne, Wong, Jerry, Nichols, Jenna, Kader, Angela, Mavis, Cory, Anampa-Guzmán, Andrea, Sait, Sheila Jani, Block, AnneMarie, Przespolewski, Eugene, Mohr, Alice, Lund, Ian, McWhite, Kenneth, Kostrewa, Jessica, DeMarco, Joseph, Johnson, Michael, Darrall, Andrea, Thomas, Roshneke, Sundaram, Suchitra, Ghione, Paola, Hutson, Alan, Hernandez-Ilizaliturri, Francisco J.

“…•Addition of carfilzomib to R-ICE is well tolerated in patients with relapsed/refractory DLBCL.•Patients with non-GCB DLBCL benefit significantly from C-R-ICE…”
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Inhibition of LSD1 in MDS progenitors restores differentiation of CD141 Hi conventional dendritic cells by Srivastava, Pragya, Tzetzo, Stephanie L, Gomez, Eduardo Cortes, Eng, Kevin H, Jani Sait, Sheila N, Kuechle, Joseph B, Singh, Prashant K, De Jong, Kitty, Wiatrowski, Kyle R, Peresie, Jennifer, Dimitroff, Ava, Lynch, Miranda L, Wang, Jianmin, Abrams, Scott I, Griffiths, Elizabeth A, Nemeth, Michael J

“…The use of immunotherapy to treat patients with myelodysplastic syndromes (MDS) shows promise but is limited by our incomplete understanding of the immunologic…”
Get full text

Rhabdomyosarcoma of the cervix in sisters by Villella, Jeannine A., Bogner, Paul N., Jani-Sait, Sheila N., Block, Anne Marie W., Lele, Shashikant

“…Pediatric embryonal heterologous rhabdomyosarcoma of the cervix is a rare tumor. We present an interesting clinico-pathologic situation of two sisters…”
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Chromosome mapping and organization of the human β-galactoside α2,6-sialyltransferase gene : differential and cell-type specific usage of upstream exon sequences in B-lymphoblastoid cells by XUECHENG WANG, VERTINO, A, EDDY, R. L, BYERS, M. G, JANI-SAIT, S. N, SHOWS, T. B, LAU, J. T. Y

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Unusual B-Lymphoid Blastic Crisis as Initial Presentation of Chronic Myeloid Leukemia Imposes Diagnostic Challenges by Momen, Nouran, Baysal, Bora, Jani Sait, Sheila, Tario, Joseph, Qian, You-Wen

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Type I procollagen COOH-terminal proteinase enhancer protein: identification, primary structure, and chromosomal localization of the cognate human gene (PCOLCE) by Takahara, K, Kessler, E, Biniaminov, L, Brusel, M, Eddy, R L, Jani-Sait, S, Shows, T B, Greenspan, D S

“…Type I procollagen COOH-terminal proteinase (C-proteinase) enhancer, a glycoprotein that binds to the COOH-terminal propeptide of type I procollagen and…”
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