Search Results - "Sainz, Yolanda"
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1
Natural estrogens enhance the engraftment of human hematopoietic stem and progenitor cells in immunodeficient mice
Published in Haematologica (Roma) (01-06-2021)“…Hematopoietic Stem and Progenitor Cells are crucial in the maintenance of lifelong production of all blood cells. These Stem Cells are highly regulated to…”
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2
Improved Methodologies for the Preparation of Highly Substituted Pyridines
Published in Journal of organic chemistry (25-11-2005)“…Two separate strategies have been developed for the preparation of highly substituted pyridines from 1,2,4-triazines via the inverse-electron-demand…”
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3
Tandem oxidation processes for the regioselective preparation of 5-substituted and 6-substituted 1,2,4-triazines
Published in Tetrahedron letters (05-06-2006)“…α-Hydroxyketones undergo MnO 2-mediated oxidation, followed by in situ trapping with 2-pyridylamidrazone, to give 3-pyridyl-5-substituted 1,2,4-triazines in a…”
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4
Novel Antiprotozoal Products: Imidazole and Benzimidazole N-Oxide Derivatives and Related Compounds
Published in Archiv der Pharmazie (Weinheim) (01-05-2004)“…The syntheses and biological evaluation of the first anti‐protozoa imidazole N‐oxide and benzimidazole N‐oxide and their derivatives are reported. They were…”
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5
Hypoxia-Selective Agents Derived from Quinoxaline 1,4-Di-N-oxides
Published in Journal of medicinal chemistry (01-05-1995)“…Hypoxic cells, which are a common feature of solid tumors, but not normal tissues, are resistant to both anticancer drugs and radiation therapy. Thus the…”
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6
New quinoxalinecarbonitrile 1,4-di-N-oxide derivatives as hypoxic-cytotoxic agents
Published in European journal of medicinal chemistry (2000)“…We report the synthesis and biological in vitro activities of 16 new 2-quinoxalinecarbonitrile 1,4-di-N-oxides. These compounds present new basic lateral…”
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7
Hypoxia-Selective Agents Derived from 2-Quinoxalinecarbonitrile 1,4-Di-N-oxides. 2
Published in Journal of medicinal chemistry (01-10-1995)“…Hypoxic cells are an important target for antitumor therapy because tumors are typically characterized by such cells. Virtually all tumors which are present as…”
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8
New hypoxia-selective cytotoxines derived from quinoxaline 1,4-dioxides
Published in Journal of heterocyclic chemistry (01-07-1995)“…A new series of quinoxaline 1,4‐dioxides, structurally related to the benzotriazine tirapazamine 1 have been prepared starting from 5,6‐dichlorobenzofuroxane…”
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9
La regulación inglesa de la responsabilidad por los daños causados por animales. Un estudio comparado con el Derecho español
Published in InDret (01-09-2013)Get full text
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10
Synthesis and antituberculosis activity of some new 2-quinoxalinecarbonitriles
Published in Farmaco (Società chimica italiana : 1989) (01-08-1998)“…Tuberculosis, an ancient disease undergoing recent control by public hygiene and drug therapy, has experienced a recrudescence throughout the world. New and…”
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Anti-Mycobacterium tuberculosis agents derived from quinoxaline-2-carbonitrile and quinoxaline-2-carbonitrile 1,4-di-N-oxide
Published in Arzneimittel-Forschung (01-01-2002)“…In this paper new quinoxaline derivatives with different substituents in positions 3, 6, 7 and 8 are reported. Their biological activities against…”
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12
New quinoxaline 1,4-di-N-oxides for treatment of tuberculosis
Published in Arzneimittel-Forschung (01-01-1999)“…Some quinoxaline 1,4-di-N-oxides derivatives with very different substituents in 2, 3, 6 and 7 positions have been synthesized in order to obtain new hypoxia…”
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