Search Results - "Sainz, Yolanda"

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    Improved Methodologies for the Preparation of Highly Substituted Pyridines by Fernández Sainz, Yolanda, Raw, Steven A, Taylor, Richard J. K

    Published in Journal of organic chemistry (25-11-2005)
    “…Two separate strategies have been developed for the preparation of highly substituted pyridines from 1,2,4-triazines via the inverse-electron-demand…”
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  3. 3

    Tandem oxidation processes for the regioselective preparation of 5-substituted and 6-substituted 1,2,4-triazines by Laphookhieo, Surat, Jones, Stuart, Raw, Steven A., Sainz, Yolanda Fernández, Taylor, Richard J.K.

    Published in Tetrahedron letters (05-06-2006)
    “…α-Hydroxyketones undergo MnO 2-mediated oxidation, followed by in situ trapping with 2-pyridylamidrazone, to give 3-pyridyl-5-substituted 1,2,4-triazines in a…”
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    Novel Antiprotozoal Products: Imidazole and Benzimidazole N-Oxide Derivatives and Related Compounds by Aguirre, Gabriela, Boiani, Mariana, Cerecetto, Hugo, Gerpe, Alejandra, González, Mercedes, Sainz, Yolanda Fernández, Denicola, Ana, de Ocáriz, Carmen Ochoa, Nogal, Juan José, Montero, David, Escario, José Antonio

    Published in Archiv der Pharmazie (Weinheim) (01-05-2004)
    “…The syntheses and biological evaluation of the first anti‐protozoa imidazole N‐oxide and benzimidazole N‐oxide and their derivatives are reported. They were…”
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    Hypoxia-Selective Agents Derived from Quinoxaline 1,4-Di-N-oxides by Monge, Antonio, Palop, Juan A, de Cerain, Adela Lopez, Senador, Virginia, Martinez, Francisco J, Sainz, Yolanda, Narro, Susana, Garcia, Estrella, de Miguel, Carlos

    Published in Journal of medicinal chemistry (01-05-1995)
    “…Hypoxic cells, which are a common feature of solid tumors, but not normal tissues, are resistant to both anticancer drugs and radiation therapy. Thus the…”
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    New quinoxalinecarbonitrile 1,4-di-N-oxide derivatives as hypoxic-cytotoxic agents by Ortega, Miguel Ángel, Morancho, María José, Martínez-Crespo, Francisco Javier, Sainz, Yolanda, Montoya, María Elena, López de Ceráin, Adela, Monge, Antonio

    “…We report the synthesis and biological in vitro activities of 16 new 2-quinoxalinecarbonitrile 1,4-di-N-oxides. These compounds present new basic lateral…”
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  7. 7

    Hypoxia-Selective Agents Derived from 2-Quinoxalinecarbonitrile 1,4-Di-N-oxides. 2 by Monge, Antonio, Martinez-Crespo, Francisco J, Lopez de Cerain, Adela, Palop, Juan A, Narro, Susana, Senador, Virginia, Marin, Ana, Sainz, Yolanda, Gonzalez, Mercedes

    Published in Journal of medicinal chemistry (01-10-1995)
    “…Hypoxic cells are an important target for antitumor therapy because tumors are typically characterized by such cells. Virtually all tumors which are present as…”
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    New hypoxia-selective cytotoxines derived from quinoxaline 1,4-dioxides by Monge, A., Palop, J. A., González, Mercedes, Martínez-Crespo, F. J., De Ceráin, Adela López, Sáinz, Yolanda, Narro, Susana, Barker, A. J., Hamilton, E.

    Published in Journal of heterocyclic chemistry (01-07-1995)
    “…A new series of quinoxaline 1,4‐dioxides, structurally related to the benzotriazine tirapazamine 1 have been prepared starting from 5,6‐dichlorobenzofuroxane…”
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    Synthesis and antituberculosis activity of some new 2-quinoxalinecarbonitriles by Montoya, M.Elena, Sainz, Yolanda, Ortega, M.Angel, Lopez De Cerain, Adela, Monge, Antonio

    Published in Farmaco (Società chimica italiana : 1989) (01-08-1998)
    “…Tuberculosis, an ancient disease undergoing recent control by public hygiene and drug therapy, has experienced a recrudescence throughout the world. New and…”
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    Anti-Mycobacterium tuberculosis agents derived from quinoxaline-2-carbonitrile and quinoxaline-2-carbonitrile 1,4-di-N-oxide by ORTEGA, Miguel Angel, SAINZ, Yolanda, MONTOYA, Maria Elena, JASO, Andrés, ZARRANZ, Belén, ALDANA, Ignacio, MONGE, Antonio

    Published in Arzneimittel-Forschung (01-01-2002)
    “…In this paper new quinoxaline derivatives with different substituents in positions 3, 6, 7 and 8 are reported. Their biological activities against…”
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  12. 12

    New quinoxaline 1,4-di-N-oxides for treatment of tuberculosis by SAINZ, Y, MONTOYA, M. E, MARTINEZ-CRESPO, F. J, ORTEGA, M. A, LOPEZ DE CERAIN, A, MONGE, A

    Published in Arzneimittel-Forschung (01-01-1999)
    “…Some quinoxaline 1,4-di-N-oxides derivatives with very different substituents in 2, 3, 6 and 7 positions have been synthesized in order to obtain new hypoxia…”
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