Search Results - "Sainteny, F"

Regulation of Id Gene Expression during Embryonic Stem Cell-Derived Hematopoietic Differentiation by Nogueira, M.M., Mitjavila-Garcia, M.T., Le Pesteur, F., Filippi, M.D., Vainchenker, W., Dubart Kupperschmitt, A., Sainteny, F.

“…To elucidate the role of helix-loop-helix (HLH) Id proteins in hematopoietic differentiation, we used a model of embryonic stem (ES) cell differentiation in…”
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The tetrapeptide Acetyl-N-Ser-Asp-Lys-Pro (goralatide) protects from doxorubicin-induced toxicity : Improvement in mice survival and protection of bone marrow stem cells and progenitors by MASSE, A, RAMIREZ, L. H, SAINTENY, F, CARDE, P, BINDOULA, G, GRILLON, C, WDZIECZAK-BAKALA, J, RADDASSI, K, DESCHAMPS DE PAILLETTE, E. D, MENCIA-HUERTA, J. M, KOSCIELNY, S, POTIER, P

“…The tetrapeptide Acetyl-N-Ser-Asp-Lys-Pro (AcSDKP or Goralatide), a physiological regulator of hematopoiesis, inhibits the entry into the S-phase of murine and…”
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The Mpl-ligand is involved in the growth-promoting activity of the murine stromal cell line MS-5 on ES cell-derived hematopoiesis by Mitjavila, M T, Filippi, M D, Cohen-Solal, K, Le Pesteur, F, Vainchenker, W, Sainteny, F

“…We investigated the ability of the murine stromal cell line MS-5 to enhance the hematopoietic potential of embryonic stem (ES) cells. The presence of…”
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Further studies on the biological activities of the CFU-S inhibitory tetrapeptide AcSDKP. II. Unresponsiveness of isolated adult rat hepatocytes, 3T3, FDC-P2, and K562 cell lines to AcSDKP. Possible involvement of intermediary cell(s) in the mechanism of AcSDKP action by Lauret, E, Dumenil, D, Miyanomae, T, Sainteny, F

“…Because the molecular mechanisms of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP; an inhibitor of spleen colony-forming unit [CFU-S] DNA synthesis) are…”
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Role of Adhesion Molecules in the Homing and Mobilization of Murine Hematopoietic Stem and Progenitor Cells by Vermeulen, Monica, Le Pesteur, Françoise, Gagnerault, Marie-Claude, Mary, Jean-Yves, Sainteny, Françoise, Lepault, Françoise

“…Bone marrow (BM) transplantation still must overcome multiple difficulties and should benefit from better understanding of stem-cell homing and mobilization…”
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In vitro purging of bone marrow with mafosfamide synergizes with in vivo chemotherapy to delay the hematological recovery in a murine model of autologous bone marrow transplantation by Lopez, M, Mary, J Y, Sainteny, F

“…Very long-lasting leukopenias and thrombocytopenias have been observed in patients submitted to transplantation of autologous bone marrow incubated in vitro…”
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Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells by VERMEULEN, M, LE PESTEUR, F, GAGNERAULT, M.-C, MARY, J.-Y, SAINTENY, F, LEPAULT, F

“…Bone marrow (BM) transplantation still must overcome multiple difficulties and should benefit from better understanding of stem-cell homing and mobilization…”
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Inhibition of angiotensin I–converting enzyme induces radioprotection by preserving murine hematopoietic short-term reconstituting cells by Charrier, Sabine, Michaud, Annie, Badaoui, Sabrina, Giroux, Sébastien, Ezan, Eric, Sainteny, Françoise, Corvol, Pierre, Vainchenker, William

“…Angiotensin I–converting enzyme (ACE) inhibitors can affect hematopoiesis by several mechanisms including inhibition of angiotensin II formation and increasing…”
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Lack of differential sensitivity of normal hematopoietic stem cells and murine lymphoblastic leukemic cells to a lysosomotropic agent, N-dodecyl morpholine by Lopez, M, Sainteny, F, Kinsky, R, Bony, V

“…The effect of N-dodecyl morpholine (NDM), a lysosomotropic compound, on the clonogenic capacity of GK15, Sp2.0, Hb131, and L1210 lymphoblastic tumor cells and…”
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Membrane-bound Delta-4 Notch ligand reduces the proliferative activity of primitive human hematopoietic CD34 CD38 cells while maintaining their LTC-IC potential

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Notch/Delta4 Interaction in Human Embryonic Liver CD34+ CD38− Cells: Positive Influence on BFU‐E Production and LTC‐IC Potential Maintenance by Dando, Jonathan S., Tavian, Manuela, Catelain, Cyril, Poirault, Sonia, Bennaceur‐Griscelli, Annelise, Sainteny, Françoise, Vainchenker, William, Péault, Bruno, Lauret, Evelyne

“…We investigated whether Notch signaling pathways have a role in human developmental hematopoiesis. In situ histochemistry analysis revealed that Notch1, 2, and…”
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Constitutive and specific activation of STAT3 by BCR-ABL in embryonic stem cells by COPPO, Paul, DUSANTER-FOURT, Isabelle, SAINTENY, Francoise, TURHAN, Ali G, MILLOT, Gael, NOGUEIRA, Maria Manuela, DUGRAY, Aymeric, BONNET, Marie Laure, MITJAVILA-GARCIA, Maria Theresa, LE PESTEUR, Dominique, GUILHOT, Francosie, VAINCHENKER, William

“…BCR-ABL oncogene, the molecular hallmark of chronic myelogenous leukemia (CML) arises in a primitive hematopoietic stem cell with both differentiation and…”
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Bone marrow stem cell kinetics in transplanted AKR leukemia by Sainteny, F, Dumenil, D, Gaillard, N, Frindel, E

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Decrease in the ability of CFU-s in shielded marrow to be recruited into cell cycle after multiple irradiations: experimental results and computer simulations by Sainteny, F, Guiget, M, Mary, J Y

“…Nine doses of 1.5 Gy given to mice with one shielded leg result in very similar perturbations in shielded marrow (CFU-s kinetics whatever the source of…”
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Telomere dysfunction and telomerase reactivation in human leukemia cell lines after telomerase inhibition by the expression of a dominant-negative hTERT mutant by DELHOMMEAU, Francois, THIERRY, Antoine, FENEUX, Danièle, LAURET, Evelyne, LECLERCQ, Edwige, COURTIER, Marie Hélène, SAINTENY, Francoise, VAINCHENKER, William, BENNACEUR-GRISCELLI, Annelise

“…As activation of telomerase represents a key step in the malignant transformation process, experimental models to develop anti-telomerase drugs provide a…”
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Hematopoietic differentiation of embryonic stem cells in mice: a model to study the biology of hematopoiesis by Filippi, M D, Sainteny, F

“…The manipulation of embryonic stem (ES) cells allows to generate mice with specific alteration in any gene. This is therefore an invaluable tool for studying…”
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Restoration of the bone marrow pluripotent stem cells in AKR mice after arabinosylcytosine treatment by Sainteny, F, Dumenil, D, Frindel, E

“…The hypothesis of repression of multipotent stem cells (CFU) by leukemic cells to explain their depletion, previously demonstrated in AKR leukemic mice, was…”
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Membrane-bound Delta-4 Notch ligand reduces the proliferative activity of primitive human hematopoietic CD34+CD38low cells while maintaining their LTC-IC potential by LAURET, E, CATELAIN, C, BENNACEUR-GRISCELLI, A, TITEUX, M, POIRAULT, S, DANDO, J. S, DORSCH, M, VILLEVAL, J-L, GROSEIL, A, VAINCHENKER, W, SAINTENY, F

“…To examine the role of the Notch ligand Delta-4 on hematopoietic stem cells, human CD34+CD38low cord blood cells were cocultured on S17 cells transduced with…”
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Requirement for mitogen-activated protein kinase activation in the response of embryonic stem cell–derived hematopoietic cells to thrombopoietin in vitro by Filippi, Marie-Dominique, Porteu, Françoise, Pesteur, Françoise Le, Schiavon, Valérie, Millot, Gaël A., Vainchenker, William, de Sauvage, Frédéric J., Dubart Kupperschmitt, Anne, Sainteny, Francoise

“…Enforced expression of c-mpl in embryonic stem (ES) cells inactivated for this gene results in protein expression in all the ES cell progeny, producing cells…”
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Hematopoietic-promoting activity of the murine stromal cell line MS-5 is not related to the expression of the major hematopoietic cytokines by Kobari, L, Dubart, A, Le Pesteur, F, Vainchenker, W, Sainteny, F

“…As an approach for characterizing the molecules involved in the proliferation and differentiation of hematopoietic stem cells we have compared the ability of…”
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