Search Results - "Saini, Marco"

Advanced Ultrasound Imaging in Glioma Surgery: Beyond Gray-Scale B-mode by Del Bene, Massimiliano, Perin, Alessandro, Casali, Cecilia, Legnani, Federico, Saladino, Andrea, Mattei, Luca, Vetrano, Ignazio Gaspare, Saini, Marco, DiMeco, Francesco, Prada, Francesco

“…Glioma surgery is aimed at obtaining maximal safe tumor resection while preserving or improving patient's neurological status. For this reason, there is…”
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Fusion imaging for intra-operative ultrasound-based navigation in neurosurgery by Prada, Francesco, Del Bene, Massimiliano, Mattei, Luca, Casali, Cecilia, Filippini, Assunta, Legnani, Federico, Mangraviti, Antonella, Saladino, Andrea, Perin, Alessandro, Richetta, Carla, Vetrano, Ignazio, Moiraghi, Alessandro, Saini, Marco, DiMeco, Francesco

“…The major shortcoming of image-guided navigation systems is the use of presurgically acquired image data, which does not account for intra-operative changes…”
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639 Intra-tumor delivery of IFN-alpha by Tie-2 transduced monocytes associated with favorable 2-year survival in unmethylated MGMT GBM patients: preliminary results of TEM-GBM phase 1/2a study by Russo, Carlo, Gentner, Bernhard, Eoli, Marica, Farina, Francesca, Russo, Carlo, Anghileri, Elena, Barcella, Matteo, Brambilla, Valentina, Carrabba, Matteo, Cuccarini, Valeria, D’Alessandris, Giorgio, Meco, Francesco Di, Ferla, Valeria, Ferroli, Paolo, Gagliardi, Filippo, Legnani, Federico, Mazzoleni, Stefania, Olivi, Alessandro, Pallini, Roberto, Saini, Marco, Snider, Silvia, Mullen, Karen, Naldini, Luigi, Finocchiaro, Gaetano, Ciceri, Fabio

“…BackgroundGlioblastoma multiforme (GBM) is an incurable glial tumor affecting the central nervous system. The reported median survival and the percentage of…”
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Intraoperative Contrast-Enhanced Ultrasound for Brain Tumor Surgery by Prada, Francesco, Perin, Alessandro, Martegani, Alberto, Aiani, Luca, Solbiati, Luigi, Lamperti, Massimo, Casali, Cecilia, Legnani, Federico, Mattei, Luca, Saladino, Andrea, Saini, Marco, DiMeco, Francesco

“…Abstract BACKGROUND: Contrast-enhanced ultrasound (CEUS) is a dynamic and continuous modality that offers a real-time, direct view of vascularization patterns…”
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Piezosurgery for Infra- and Supratentorial Craniotomies in Brain Tumor Surgery by Vetrano, Ignazio G., Prada, Francesco, Perin, Alessandro, Casali, Cecilia, DiMeco, Francesco, Saini, Marco

“…Piezoelectric surgery represents an innovative technique to perform safe and effective osteotomies and is an alternative to traditional bony tissue management…”
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Multisession Radiosurgery for Sellar and Parasellar Benign Meningiomas: Long-term Tumor Growth Control and Visual Outcome by Marchetti, Marcello, Bianchi, Stefania, Pinzi, Valentina, Tramacere, Irene, Fumagalli, Maria Luisa, Milanesi, Ida Maddalena, Ferroli, Paolo, Franzini, Angelo, Saini, Marco, DiMeco, Francesco, Fariselli, Laura

“…BACKGROUND:Concern about radiation-induced optic neuropathy (RION) has governed recent thinking about the role of radiation therapy in the treatment of…”
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Intraoperative cerebral angiosonography with ultrasound contrast agents: how I do it by Prada, Francesco, Del Bene, Massimiliano, Saini, Marco, Ferroli, Paolo, DiMeco, Francesco

“…Background Intraoperative vessel visualization is highly desirable, especially when the target is related to or close to main vessels, such as in the skull…”
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CTIM-22. MEDIAN AND 2 YEARS SURVIVAL OF NEWLY DIAGNOSED UNMETHYLATED MGMT GLIOBLASTOMA PATIENTS TREATED WITH TEMFERON IMMUNO-GENE THERAPY by Eoli, Marica, Farina, Francesca, Cuccarini, Valeria, Gentner, Bernhard, Barcella, Matteo, Anghileri, Elena, Bruzzone, Maria Grazia, Carrabba, Matteo, D’Alessandris, Quintino Giorgio, DiMeco, Francesco, Ferla, Valeria, Franzin, Alberto, Ferroli, Paolo, Gagliardi, Filippo, Legnani, Francesco, Capotondo, Alessia, Mazzoleni, Stefania, Mortini, Pietro, Olivi, Alessandro, Pallini, Roberto, Patanè, Monica, Paterra, Rosina, Pollo, Bianca, Saini, Marco, Snider, Silvia, Naldini, Luigi, Russo, Carlo, Ciceri, Fabio, Finocchiaro, Gaetano

“…Abstract TEM-GBM is an open-label, Phase 1/2a dose-escalation study aimed to evaluate the safety and efficacy of a myeloid cell-targeted therapy (Temferon) in…”
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Intraoperative Cerebral Glioma Characterization with Contrast Enhanced Ultrasound by Del Bene, Massimiliano, Mattei, Luca, Prada, Francesco, Aiani, Luca, Saini, Marco, Casali, Cecilia, Filippini, Assunta, Legnani, Federico Giuseppe, Perin, Alessandro, Saladino, Andrea, Vetrano, Ignazio Gaspare, Solbiati, Luigi, Martegani, Alberto, DiMeco, Francesco

“…Background. Contrast enhanced ultrasound (CEUS) is a dynamic and continuous modality providing real-time view of vascularization and flow distribution patterns…”
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Harnessing genetically engineered hematopoietic progenitor cells to redirect the tumor immune microenvironment against glioblastoma (TEM-GBM Study) by Eoli, Marica, Gentner, Bernhard, Farina, Francesca, Anghileri, Elena, Bisdas, Sotiros, Bruzzone, Maria Grazia, Cuccarini, Valeria, D'Alessandris, Quintino Giorgio, Di Meco, Francesco, Ferroli, Paolo, Franzin, Alberto, Gagliardi, Filippo, Legnani, Federico, Saini, Marco, Olivi, Alessandro, Pallini, Roberto, Russo, Carlo, Naldini, Luigi, Finocchiaro, Gaetano, Ciceri, Fabio

“…2040 Background: Immunotherapies represent powerful tools that are transforming the treatment of many cancers. However, immune dysfunction in cancer is…”
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CTIM-26. IMPACT ON SURVIVAL OF INTERFERON-ALPHA DELIVERY IN GLIOBLASTOMA WITH UNMETHYLATED MGMT BY IMMUNO-GENE THERAPY WITH TEMFERON by Finocchiaro, Gaetano, Cuccarini, Valeria, Gentner, Bernhard, Capotondo, Alessia, Farina, Francesca, Naldini, Matteo Maria, Barcella, Matteo, Anghileri, Elena, Bruzzone, Maria Grazia, Carrabba, Matteo, D'alessandris, Quintino Giorgio, Meco, Francesco Di, Ferla, Valeria, Franzin, Alberto, Ferroli, Paolo, Gagliardi, Filippo, Legnani, Federico, Mazzoleni, Stefania, Mortini, Pietro, Olivi, Alessandro, Pallini, Roberto, Patanè, Monica, Paterra, Rosina, Pollo, Bianca, Saini, Marco, Snider, Silvia, Mullen, Karen, Naldini, Luigi, Russo, Carlo, Ciceri, Fabio, Eoli, Marica

“…Abstract Temferon is an ex vivo gene therapy consisting of autologous Hematopoietic Stem Progenitor Cells (HSPCs) genetically modified with a lentiviral vector…”
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Reprogramming Macrophages Using Autologous Hematopoietic Stem Cells As Immunotherapy for Glioblastoma: TEM-GBM Study (NCT03866109) by Farina, Francesca, Gentner, Bernhard, Finocchiaro, Gaetano, Eoli, Marica, Capotondo, Alessia, Anghileri, Elena, Barcella, Matteo, Brambilla, Valentina, Bruzzone, Maria Grazie, Carrabba, Matteo Giovanni, Cuccarini, Valeria, D'Alessandris, Giorgio, Di Meco, Francesco, Ferla, Valeria, Franzin, Alberto, Ferroli, Paolo, Gagliardi, Filippo, Legnani, Federico, Mazzoleni, Stefania, Mortini, Pietro, Naldini, Matteo Maria, Olivi, Alessandro, Pallini, Roberto, Patanè, Monica, Paterra, Rosina, Pollo, Bianca, Saini, Marco, Snider, Silvia, Zambanini, Andrew, Naldini, Luigi, Russo, Carlo, Ciceri, Fabio

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Dynamic assessment of venous anatomy and function in neurosurgery with real-time intraoperative multimodal ultrasound: technical note by Prada, Francesco, Del Bene, Massimiliano, Mauri, Giovanni, Lamperti, Massimo, Vailati, Davide, Richetta, Carla, Saini, Marco, Santuari, Davide, Kalani, M Yashar S, DiMeco, Francesco

“…The relevance of the cerebral venous system is often underestimated during neurosurgical procedures. Damage to this draining system can have catastrophic…”
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Intraoperative Strain Elastosonography in Brain Tumor Surgery by Prada, Francesco, Del Bene, Massimiliano, Rampini, Angela, Mattei, Luca, Casali, Cecilia, Vetrano, Ignazio Gaspare, Gennari, Antonio Giulio, Sdao, Silvana, Saini, Marco, Sconfienza, Luca Maria, DiMeco, Francesco

“…Abstract BACKGROUND Sonoelastography is an ultrasound imaging technique able to assess mechanical properties of tissues. Strain elastography (SE) is a…”
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Intraoperative Navigated Angiosonography for Skull Base Tumor Surgery by Prada, Francesco, Bene, Massimiliano Del, Casali, Cecilia, Saladino, Andrea, Legnani, Federico Giuseppe, Perin, Alessandro, Moiraghi, Alessandro, Richetta, Carla, Rampini, Angela, Mattei, Luca, Vetrano, Ignazio Gaspare, Fornaro, Riccardo, Saini, Marco, Martegani, Alberto, DiMeco, Francesco

“…Background One of the main challenges during skull base tumor surgery is identifying the relationships between the lesion and the principal intracranial…”
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Abstract CT180: Changes in immunologic responses and in the tumor microenvironment in patients with glioblastoma multiforme treated with IFN-a immune cell and gene therapy (TEM-GBM_001 Study) by Gentner, Bernhard, Finocchiaro, Gaetano, Farina, Francesca, Capotondo, Alessia, Eoli, Marica, Anghileri, Elena, Ganzetti, Maya, Carabba, Matteo, Cuccarini, Valeria, Meco, Francesco Di, Legnani, Federico, Pollo, Bianca, Bruzzone, Maria Grazia, Saini, Marco, Ferroli, Paolo, Pallini, Roberto, Olivi, Alessandro, Paterra, Rosina, Garramone, Mariagrazia, Mazzoleni, Stefania, Brambilla, Valentina, Magnani, Tiziana, Antonarelli, Gabriele, Naldini, Matteo, Barcella, Matteo, Russo, Carlo, Naldini, Luigi, Ciceri, Fabio

“…Abstract Genetically modified cell-based therapies are of increasing relevance in immuno-oncology due to their potential for tumor specificity, long term…”
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A phase I-IIa study of genetically modified Tie-2 expressing monocytes in patients with glioblastoma multiforme (TEM-GBM Study) by Finocchiaro, Gaetano, Gentner, Bernhard, Farina, Francesca, Capotondo, Alessia, Eoli, Marica, Anghileri, Elena, Carabba, Matteo Giovanni, Cuccarini, Valeria, DI Meco, Francesco, Legnani, Federico, Pollo, Bianca, Bruzzone, Maria Grazia, Saini, Marco, Ferroli, Paolo, Pallini, Roberto, Olivi, Alessandro, Mazzoleni, Stefania, Russo, Carlo, Naldini, Luigi, Ciceri, Fabio

“…Abstract only 2532 Background: Genetically modified cell-based therapies are relevant in immuno-oncology due to their potential for tumor specificity &…”
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TEM-GBM: An Open-Label, Phase I/IIa Dose-Escalation Study Evaluating the Safety and Efficacy of Genetically Modified Tie-2 Expressing Monocytes to Deliver IFN-α within Glioblastoma Tumor Microenvironment by Gentner, Bernhard, Finocchiaro, Gaetano, Farina, Francesca, Eoli, Marica, Alessia, Capotondo, Anghileri, Elena, Antonarelli, Gabriele, Barcella, Matteo, Bruzzone, Maria Grazia, Carrabba, Matteo Giovanni, Cuccarini, Valeria, D'Alessandris, Giorgio, Di Meco, Francesco, Ferla, Valeria, Ferroli, Paolo, Gagliardi, Filippo, Garramone, Mariagrazia, Legnani, Federico, Mortini, Pietro, Naldini, Matteo Maria, Olivi, Alessandro, Pallini, Roberto, Patanè, Monica, Paterra, Rosina, Pollo, Bianca, Saini, Marco, Snider, Silvia, Brambilla, Valentina, Magnani, Tiziana, Mazzoleni, Stefania, Bashir, Zahid, Russo, Carlo, Naldini, Luigi, Ciceri, Fabio

“…Background: We developed a macrophage-based treatment relying on ex vivo transduction of autologous hematopoietic stem and progenitor cells (HSPC) to express…”
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Peri-operative prognostic factors for primary skull base chordomas: results from a single-center cohort by La Corte, Emanuele, Broggi, Morgan, Raggi, Alberto, Schiavolin, Silvia, Acerbi, Francesco, Danesi, Giovanni, Farinotti, Mariangela, Felisati, Giovanni, Maccari, Alberto, Pollo, Bianca, Saini, Marco, Toppo, Claudia, Valvo, Francesca, Ghidoni, Riccardo, Bruzzone, Maria Grazia, DiMeco, Francesco, Ferroli, Paolo

“…Background Skull base chordomas (SBC) are rare malignant tumors and few factors have been found to be reliable markers for clinical decision making and…”
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From Grey Scale B-Mode to Elastosonography: Multimodal Ultrasound Imaging in Meningioma Surgery—Pictorial Essay and Literature Review by Richetta, Carla, Saini, Marco, DiMeco, Francesco, Vetrano, Ignazio Gaspare, Perin, Alessandro, Saladino, Andrea, Legnani, Federico Giuseppe, Casali, Cecilia, Moiraghi, Alessandro, Del Bene, Massimiliano, Prada, Francesco, Mattei, Luca

“…The main goal in meningioma surgery is to achieve complete tumor removal, when possible, while improving or preserving patient neurological functions…”
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