Search Results - "Saini, Harpinder"
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Gold nanorod-incorporated gelatin-based conductive hydrogels for engineering cardiac tissue constructs
Published in Acta biomaterialia (01-09-2016)“…[Display omitted] The development of advanced biomaterials is a crucial step to enhance the efficacy of tissue engineering strategies for treatment of…”
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Journal Article -
2
A Human Organotypic Microfluidic Tumor Model Permits Investigation of the Interplay between Patient-Derived Fibroblasts and Breast Cancer Cells
Published in Cancer research (Chicago, Ill.) (15-06-2019)“…Tumor-stroma interactions significantly influence cancer cell metastasis and disease progression. These interactions are partly comprised of the cross-talk…”
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Journal Article -
3
Advanced Biomaterials and Microengineering Technologies to Recapitulate the Stepwise Process of Cancer Metastasis
Published in Biomaterials (01-07-2017)“…Abstract Cancer is one of the leading causes of death globally according to the World Health Organization. Although improved treatments and early diagnostics…”
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Journal Article -
4
The Role of Desmoplasia and Stromal Fibroblasts on Anti-cancer Drug Resistance in a Microengineered Tumor Model
Published in Cellular and molecular bioengineering (01-10-2018)“…Introduction Cancer associated fibroblasts (CAFs) are known to participate in anti-cancer drug resistance by upregulating desmoplasia and pro-survival…”
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Journal Article -
5
Fabrication Method of a High-Density Co-Culture Tumor-Stroma Platform to Study Cancer Progression
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…Cancer has now been established as one of the most common chronic diseases due to high mortality rate. The early stage of non-invasive tumors can now be…”
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Journal Article -
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3D Cardiac Microtissues Encapsulated with the Co-Culture of Cardiomyocytes and Cardiac Fibroblasts
Published in Advanced healthcare materials (01-09-2015)“…Cardiac tissue engineering has major applications in regenerative medicine, disease modeling and biological studies. Despite the significance, numerous…”
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Journal Article -
7
The role of tumor-stroma interactions on desmoplasia and tumorigenicity within a microengineered 3D platform
Published in Biomaterials (01-07-2020)“…The tumor microenvironment has been demonstrated to play a crucial role in modulating cancer progression. Amongst various cell types within the tumor…”
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Journal Article -
8
Reversible Control of Gelatin Hydrogel Stiffness by Using DNA Crosslinkers
Published in Chembiochem : a European journal of chemical biology (14-05-2021)“…Biomaterials with dynamically tunable properties are critical for a range of applications in regenerative medicine and basic biology. In this work, we show the…”
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Journal Article -
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A High-density 3D Microengineered Platform to Study the Role of Tumor-Stroma Interactions on Desmoplasia and Breast Cancer Progression
Published 01-01-2019“…Solid tumors advance from benign stage to a deadly metastatic state due to the complex interaction between cancer cells and tumor microenvironment (TME)…”
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Dissertation -
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Engineering Three Dimensional Cardiac Micro-Tissues Encapsulated with the Co-Culture of Cardiomyocytes and Cardiac Fibroblasts
Published 01-01-2015“…Cardiac tissue engineering has major applications in regenerative medicine, disease modeling and fundamental biological studies. Despite the significance,…”
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Dissertation -
11
Engineering Three Dimensional Cardiac Micro-Tissues Encapsulated with the Co-Culture of Cardiomyocytes and Cardiac Fibroblasts
Get full text
Dissertation