Search Results - "Sailer, Cooper J."
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PD-1Hi CAR-T cells provide superior protection against solid tumors
Published in Frontiers in immunology (14-06-2023)“…Chimeric antigen receptor (CAR)-T cell therapy has emerged as a promising treatment option for several hematologic cancers. However, efforts to achieve the…”
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Journal Article -
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318 Building A Better CAR: Improving CAR-T Trafficking in Cancer Therapy
Published in Journal of clinical and translational science (01-04-2022)“…OBJECTIVES/GOALS: #NAME? METHODS/STUDY POPULATION: Cell culture & protein identification: human T cells were purified from healthy blood, then activated &…”
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ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors
Published in Nature immunology (01-06-2023)“…Adoptive transfer of genetically engineered chimeric antigen receptor (CAR) T cells is becoming a promising treatment option for hematological malignancies…”
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Immunoengineering can overcome the glycocalyx armour of cancer cells
Published in Nature materials (01-03-2024)“…Cancer cell glycocalyx is a major line of defence against immune surveillance. However, how specific physical properties of the glycocalyx are regulated on a…”
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Platelet-activating factor (PAF) promotes immunosuppressive neutrophil differentiation within tumors
Published in Proceedings of the National Academy of Sciences - PNAS (27-08-2024)“…Chronic inflammatory milieu in the tumor microenvironment (TME) leads to the recruitment and differentiation of myeloid-derived suppressor cells (MDSCs)…”
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6
PD-1 Hi CAR-T cells provide superior protection against solid tumors
Published in Frontiers in immunology (2023)“…Chimeric antigen receptor (CAR)-T cell therapy has emerged as a promising treatment option for several hematologic cancers. However, efforts to achieve the…”
Get full text
Journal Article