Search Results - "Saiki, R."

High juvenile hormone titre and abdominal activation of JH signalling may induce reproduction of termite neotenics by Saiki, R, Gotoh, H, Toga, K, Miura, T, Maekawa, K

“…Termite castes are a key example of polyphenism, in which reproductive division of labour is clearly seen in colonies. The reproductive castes in termites…”
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P466: AMPLIFIED EPOR/JAK2 GENES DEFINE A UNIQUE SUBTYPE OF ACUTE ERYTHROID LEUKEMIA by Takeda, J., Yoshida, K., Nakagawa, M., Nannya, Y., Yoda, A., Saiki, R., Ochi, Y., Zhao, L., Okuda, R., Qi, X., Mori, T., Kon, A., Chiba, K., Tanaka, H., Shiraishi, Y., Kuo, M.‐C., Kerr, C., Nagata, Y., Morishita, D., Hiramoto, N., Hangaishi, A., Nakazawa, H., Ishiyama, K., Miyano, S., Chiba, S., Miyazaki, Y., Kitano, T., Usuki, K., Sezaki, N., Tsurumi, H., Miyawaki, S., Maciejewski, J., Ishikawa, T., Ohyashiki, K., Ganser, A., Heuser, M., Thol, F., Shih, L.‐Y., Takaori−Kondo, A., Makishima, H., Ogawa, S.

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A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions by HIGUCHI, R, KRUMMEL, B, SAIKI, R. K

“…Specific, end-labeled DNA fragments can be simply and rapidly prepared using the polymerase chain reaction (PCR). Such fragments are suitable for use in DNase…”
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Genetic Analysis of Amplified DNA with Immobilized Sequence-Specific Oligonucleotide Probes by Saiki, Randall K., Walsh, P. Sean, Levenson, Corey H., Erlich, Henry A.

“…The analysis of DNA for the presence of particular mutations or polymorphisms can be readily accomplished by differential hybridization with sequence-specific…”
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Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma by TADA, M, OMATA, M, KAWAI, S, SAISHO, H, OHTO, M, SAIKI, R. K, SNINSKY, J. J

“…Pancreatic adenocarcinomas are known to have a high incidence of K-ras gene mutations. Differential diagnosis of pancreatic cancer and chronic pancreatitis…”
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Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase by Saiki, Randall K., Gelfand, David H., Stoffel, Susanne, Scharf, Stephen J., Higuchi, Russell, Horn, Glenn T., Mullis, Kary B., Erlich, Henry A.

“…A thermostable DNA polymerase was used in an in vitro DNA amplification procedure, the polymerase chain reaction. The enzyme, isolated from Thermus aquaticus,…”
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Isolation, Characterization, and Expression in Escherichia coli of the DNA Polymerase Gene from Thermus aquaticus by Lawyer, F C, Stoffel, S, Saiki, R K, Myambo, K, Drummond, R, Gelfand, D H

“…The thermostable properties of the DNA polymerase activity from Thermus aquaticus (Taq) have contributed greatly to the yield, specificity, automation, and…”
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P741: DDX41 MUTATIONS DEFINE A UNIQUE SUBTYPE OF MYELOID NEOPLASMS by Makishima, H., Saiki, R., Nannya, Y., Korotev, S., Gurnari, C., Takeda, J., Momozawa, Y., Best, S., Krishnamurthy, P., Yoshizato, T., Atsuta, Y., Shiozawa, Y., Iijima-Yamashita, Y., Yoshida, K., Shiraishi, Y., Nagata, Y., Kakiuchi, N., Onizuka, M., Chiba, K., Tanaka, H., Kon, A., Ochi, Y., Nakagawa, M., Okuda, R., Mori, T., Itonaga, H., Miyazaki, Y., Sanada, M., Tsurumi, H., Kasahara, S., Müller-Tidow, C., Takaori-Kondo, A., Ohyashiki, K., Kiguchi, T., Matsuda, F., Jansen, J., Polprasert, C., Miyano, S., Malcovati, L., Haferlach, T., Kubo, M., Cazzola, M., Kulasekararaj, A., Godley, L., Maciejewski, J., Ogawa, S.

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Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia by Saiki, Randall K., Scharf, Stephen, Faloona, Fred, Mullis, Kary B., Horn, Glenn T., Erlich, Henry A., Arnheim, Norman

“…Two new methods were used to establish a rapid and highly sensitive prenatal diagnostic test for sickle cell anemia. The first involves the primer-mediated…”
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Phenotypes of Fission Yeast Defective in Ubiquinone Production Due to Disruption of the Gene for p-Hydroxybenzoate Polyprenyl Diphosphate Transferase by Uchida, N, Suzuki, K, Saiki, R, Kainou, T, Tanaka, K, Matsuda, H, Kawamukai, M

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes by Saiki, Randall K, Bugawan, Teodorica L, Horn, Glenn T, Mullis, Kary B, Erlich, Henry A

“…Allelic sequence variation has been analysed by synthetic oligonucleotide hybridization probes which can detect single base substitutions in human genomic DNA…”
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Analysis of RAS Gene Mutations in Acute Myeloid Leukemia by Polymerase Chain Reaction and Oligonucleotide Probes by Farr, Christine J., Saiki, Randall K., Erlich, Henry A., McCormick, Frank, Marshall, Christopher J.

“…In vitro DNA amplification followed by oligonucleotide dot blot analysis were used to study RAS gene mutations in acute myeloid leukemia (AML). Fifty-two…”
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Amplification and analysis of DNA sequences in single human sperm and diploid cells by Li, Honghua, Gyllensten, Ulf B, Cui, Xiangfeng, Saiki, Randall K, Erlich, Henry A, Arnheim, Norman

“…The use of the polymerase chain reaction for analysing DNA sequences in individual diploid cells and human sperm shows that two genetic loci can be…”
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Specific enzymatic amplification of DNA in vitro: the polymerase chain reaction by Mullis, K, Faloona, F, Scharf, S, Saiki, R, Horn, G, Erlich, H

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Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes by Bernard, Elsa, Nannya, Yasuhito, Hasserjian, Robert P., Devlin, Sean M., Tuechler, Heinz, Medina-Martinez, Juan S., Yoshizato, Tetsuichi, Shiozawa, Yusuke, Saiki, Ryunosuke, Malcovati, Luca, Levine, Max F., Arango, Juan E., Zhou, Yangyu, Solé, Francesc, Cargo, Catherine A., Haase, Detlef, Creignou, Maria, Germing, Ulrich, Zhang, Yanming, Gundem, Gunes, Sarian, Araxe, van de Loosdrecht, Arjan A., Jädersten, Martin, Tobiasson, Magnus, Kosmider, Olivier, Follo, Matilde Y., Thol, Felicitas, Pinheiro, Ronald F., Santini, Valeria, Kotsianidis, Ioannis, Boultwood, Jacqueline, Santos, Fabio P. S., Schanz, Julie, Kasahara, Senji, Ishikawa, Takayuki, Tsurumi, Hisashi, Takaori-Kondo, Akifumi, Kiguchi, Toru, Polprasert, Chantana, Bennett, John M., Klimek, Virginia M., Savona, Michael R., Belickova, Monika, Ganster, Christina, Palomo, Laura, Sanz, Guillermo, Ades, Lionel, Della Porta, Matteo Giovanni, Elias, Harold K., Smith, Alexandra G., Werner, Yesenia, Patel, Minal, Viale, Agnès, Vanness, Katelynd, Neuberg, Donna S., Stevenson, Kristen E., Menghrajani, Kamal, Bolton, Kelly L., Fenaux, Pierre, Pellagatti, Andrea, Platzbecker, Uwe, Heuser, Michael, Valent, Peter, Chiba, Shigeru, Miyazaki, Yasushi, Finelli, Carlo, Voso, Maria Teresa, Shih, Lee-Yung, Fontenay, Michaela, Jansen, Joop H., Cervera, José, Atsuta, Yoshiko, Gattermann, Norbert, Ebert, Benjamin L., Bejar, Rafael, Greenberg, Peter L., Cazzola, Mario, Hellström-Lindberg, Eva, Ogawa, Seishi, Papaemmanuil, Elli

“…Tumor protein p53 ( TP53 ) is the most frequently mutated gene in cancer 1 , 2 . In patients with myelodysplastic syndromes (MDS), TP53 mutations are…”
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Germ line DDX41 mutations define a unique subtype of myeloid neoplasms by Makishima, Hideki, Saiki, Ryunosuke, Nannya, Yasuhito, Korotev, Sophia, Gurnari, Carmelo, Takeda, June, Momozawa, Yukihide, Best, Steve, Krishnamurthy, Pramila, Yoshizato, Tetsuichi, Atsuta, Yoshiko, Shiozawa, Yusuke, Iijima-Yamashita, Yuka, Yoshida, Kenichi, Shiraishi, Yuichi, Nagata, Yasunobu, Kakiuchi, Nobuyuki, Onizuka, Makoto, Chiba, Kenichi, Tanaka, Hiroko, Kon, Ayana, Ochi, Yotaro, Nakagawa, Masahiro M., Okuda, Rurika, Mori, Takuto, Yoda, Akinori, Itonaga, Hidehiro, Miyazaki, Yasushi, Sanada, Masashi, Ishikawa, Takayuki, Chiba, Shigeru, Tsurumi, Hisashi, Kasahara, Senji, Müller-Tidow, Carsten, Takaori-Kondo, Akifumi, Ohyashiki, Kazuma, Kiguchi, Toru, Matsuda, Fumihiko, Jansen, Joop H., Polprasert, Chantana, Blombery, Piers, Kamatani, Yoichiro, Miyano, Satoru, Malcovati, Luca, Haferlach, Torsten, Kubo, Michiaki, Cazzola, Mario, Kulasekararaj, Austin G., Godley, Lucy A., Maciejewski, Jaroslaw P., Ogawa, Seishi

“…•DDX41 germ line mutations explain ∼80% of known germ line predisposition to MNs in adults, and the life-long risk was ∼50%.•DDX41-mutated MDS patients rapidly…”
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Diagnosis of sickle cell anemia and beta-thalassemia with enzymatically amplified DNA and nonradioactive allele-specific oligonucleotide probes by Saiki, R K, Chang, C A, Levenson, C H, Warren, T C, Boehm, C D, Kazazian, Jr, H H, Erlich, H A

“…We have developed a simple and rapid nonradioactive method for detecting genetic variation and have applied it to the diagnosis of sickle cell anemia and…”
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Combined landscape of single-nucleotide variants and copy number alterations in clonal hematopoiesis by Saiki, Ryunosuke, Momozawa, Yukihide, Nannya, Yasuhito, Nakagawa, Masahiro M., Ochi, Yotaro, Yoshizato, Tetsuichi, Terao, Chikashi, Kuroda, Yutaka, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Niida, Atsushi, Imoto, Seiya, Matsuda, Koichi, Morisaki, Takayuki, Murakami, Yoshinori, Kamatani, Yoichiro, Matsuda, Shuichi, Kubo, Michiaki, Miyano, Satoru, Makishima, Hideki, Ogawa, Seishi

“…Clonal hematopoiesis (CH) in apparently healthy individuals is implicated in the development of hematological malignancies (HM) and cardiovascular diseases…”
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Specific DNA amplification by Erlich, H.A, Gelfand, Saiki, R.K

“…A report on the polymerase chain reaction that can synthesize millions of copies of a specific DNA sequence in a brief in vitro reaction is presented…”
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Genetic markers of male infertility: Y chromosome microdeletions and cystic fibrosis transmembrane conductance gene mutations by Sertić, J, Cvitković, P, Myers, A, Saiki, R K, Stavljenić Rukavina, A

“…Today, approximately 15% of couples have reduced fertility. In most cases the reason is male infertility, usually of genetic origin. Thus, in the context of…”
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