Search Results - "Saikali, Stephan"

Radiological-Pathological Correlation in Alzheimer's Disease: Systematic Review of Antemortem Magnetic Resonance Imaging Findings by Dallaire-Théroux, Caroline, Callahan, Brandy L, Potvin, Olivier, Saikali, Stéphan, Duchesne, Simon

“…The standard method of ascertaining Alzheimer's disease (AD) remains postmortem assessment of amyloid plaques and neurofibrillary degeneration. Vascular…”
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From the core to beyond the margin: a genomic picture of glioblastoma intratumor heterogeneity by Aubry, Marc, de Tayrac, Marie, Etcheverry, Amandine, Clavreul, Anne, Saikali, Stéphan, Menei, Philippe, Mosser, Jean

“…Glioblastoma (GB) is a highly invasive primary brain tumor that almost systematically recurs despite aggressive therapies. One of the most challenging problems…”
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DNA methylation in glioblastoma: impact on gene expression and clinical outcome by Etcheverry, Amandine, Aubry, Marc, de Tayrac, Marie, Vauleon, Elodie, Boniface, Rachel, Guenot, Frederique, Saikali, Stephan, Hamlat, Abderrahmane, Riffaud, Laurent, Menei, Philippe, Quillien, Veronique, Mosser, Jean

“…Changes in promoter DNA methylation pattern of genes involved in key biological pathways have been reported in glioblastoma. Genome-wide assessments of DNA…”
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Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis by Paré, Bastien, Lehmann, Manuela, Beaudin, Marie, Nordström, Ulrika, Saikali, Stephan, Julien, Jean-Pierre, Gilthorpe, Jonathan D., Marklund, Stefan L., Cashman, Neil R., Andersen, Peter M., Forsberg, Karin, Dupré, Nicolas, Gould, Peter, Brännström, Thomas, Gros-Louis, François

“…Aggregation of mutant superoxide dismutase 1 (SOD1) is a pathological hallmark of a subset of familial ALS patients. However, the possible role of misfolded…”
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Comparative assessment of 5 methods (methylation‐specific polymerase chain reaction, methylight, pyrosequencing, methylation‐sensitive high‐resolution melting, and immunohistochemistry) to analyze O6‐methylguanine‐DNA‐methyltranferase in a series of 100 glioblastoma patients by Quillien, Véronique, Lavenu, Audrey, Karayan‐Tapon, Lucie, Carpentier, Catherine, Labussière, Marianne, Lesimple, Thierry, Chinot, Olivier, Wager, Michel, Honnorat, Jérome, Saikali, Stephan, Fina, Frédéric, Sanson, Marc, Figarella‐Branger, Dominique

“…BACKGROUND: There is a strong need to determine the best technique for O6‐methylguanine‐DNA‐methyltranferase (MGMT) analysis, because MGMT status is currently…”
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Impact of 9p deletion and p16, Cyclin D1, and Myc hyperexpression on the outcome of anaplastic oligodendrogliomas by Michaud, Karine, de Tayrac, Marie, D'Astous, Myreille, Paquet, Claudie, Gould, Peter Vincent, Saikali, Stéphan

“…To study the presence of 9p deletion and p16, cyclin D1 and Myc expression and their respective diagnostic and prognostic interest in oligodendrogliomas. We…”
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Targeting TDP-43 Pathology Alleviates Cognitive and Motor Deficits Caused by Chronic Cerebral Hypoperfusion by Thammisetty, Sai Sampath, Renaud, Laurence, Picher-Martel, Vincent, Weng, Yuan Cheng, Calon, Frédéric, Saikali, Stephan, Julien, Jean-Pierre, Kriz, Jasna

“…Vascular dementia is one of the most common forms of dementia in aging population. However, the molecular mechanisms involved in development of disease and the…”
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Human Glioblastoma Stem-Like Cells are More Sensitive to Allogeneic NK and T Cell-Mediated Killing Compared with Serum-Cultured Glioblastoma Cells by Avril, Tony, Vauleon, Elodie, Hamlat, Abderrahmane, Saikali, Stéphan, Etcheverry, Amandine, Delmas, Caroline, Diabira, Sylma, Mosser, Jean, Quillien, Véronique

“…Glioblastoma multiforme (GBM) is the most dramatic primary brain cancer with a very poor prognosis because of inevitable disease recurrence. The median overall…”
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A Topographic Atlas of the Human Brainstem in the Ponto-Mesencephalic Junction Plane by Coulombe, Vincent, Saikali, Stephan, Goetz, Laurent, Takech, Mohamad A., Philippe, Éric, Parent, André, Parent, Martin

“…The human brainstem harbors neuronal aggregates that ensure the maintenance of several vital functions. It also acts as a major relay structure for the…”
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Automated Analysis of 1p/19q Status by FISH in Oligodendroglial Tumors: Rationale and Proposal of an Algorithm by Duval, Céline, de Tayrac, Marie, Michaud, Karine, Cabillic, Florian, Paquet, Claudie, Gould, Peter Vincent, Saikali, Stéphan

“…To propose a new algorithm facilitating automated analysis of 1p and 19q status by FISH technique in oligodendroglial tumors with software packages available…”
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Contribution of 1p, 19q, 9p and 10q Automated Analysis by FISH to the Diagnosis and Prognosis of Oligodendroglial Tumors According to WHO 2016 Guidelines by Michaud, Karine, de Tayrac, Marie, D'Astous, Myreille, Duval, Céline, Paquet, Claudie, Samassekou, Oumar, Gould, Peter Vincent, Saikali, Stéphan

“…To study the feasibility and the diagnostic and prognostic interest of automated analysis of 1p, 19q, 9p and 10q status by FISH technique in oligodendroglial…”
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Distinct effects of human glioblastoma immunoregulatory molecules programmed cell death ligand-1 (PDL-1) and indoleamine 2,3-dioxygenase (IDO) on tumour-specific T cell functions by Avril, Tony, Saikali, Stéphan, Vauleon, Elodie, Jary, Anne, Hamlat, Abderrahmane, De Tayrac, Marie, Mosser, Jean, Quillien, Véronique

“…Abstract Immunotherapy is a promising new treatment for patients suffering from glioma, in particular glioblastoma multiforme (GBM). However, tumour cells use…”
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Prognostic significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, four new markers in high-grade gliomas by de Tayrac, Marie, Saikali, Stephan, Aubry, Marc, Bellaud, Pascale, Boniface, Rachel, Quillien, Véronique, Mosser, Jean

“…Recent studies have highlighted the heterogeneity of gliomas and demonstrated that molecular and genetic analysis could help in their classification and in the…”
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Biofabrication of a three dimensional human‐based personalized neurofibroma model by Roy, Vincent, Lamontagne, Rémy, Talagas, Matthieu, Touzel‐Deschênes, Lydia, Khuong, Hélène T., Saikali, Stéphan, Dupré, Nicolas, Gros‐Louis, François

“…Neurofibromas are the most characteristic feature of neurofibromatosis type 1 (NF1), a multisystemic disorder caused by aberrations in the neurofibromin gene…”
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Post-mortem analysis of Parkinson’s disease brains after long-term deep brain stimulation of the subthalamic nucleus by Munro, Jonathan, Desmeules, Francis, Carrondo, Sylvine Cottin, Noecker, Angela, Tremblay, Marie-Ève, Gould, Peter V., Saikali, Stephan, Langlois, Mélanie, Prud’homme, Michel, McIntyre, Cameron C., Cantin, Léo, Martin, Parent

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ImmunoFISH is a reliable technique for the assessment of 1p and 19q status in oligodendrogliomas by Duval, Céline, de Tayrac, Marie, Sanschagrin, François, Michaud, Karine, Gould, Peter Vincent, Saikali, Stéphan

“…To develop a new ImmunoFISH technique for the study of oligodendrogliomas by combining a standard immunohistochemical stain using MIB-1 antibody with a…”
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A three-dimensional digital segmented and deformable brain atlas of the domestic pig by Saikali, Stéphan, Meurice, Paul, Sauleau, Paul, Eliat, Pierre-Antoine, Bellaud, Pascale, Randuineau, Gwenaelle, Vérin, Marc, Malbert, Charles-Henri

“…We used high-magnetic field (4.7 T) magnetic resonance imaging (MRI) to build the first high-resolution (100 μm × 150 μm × 100 μm) three-dimensional (3D)…”
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Braak neurofibrillary tangle staging prediction from in vivo MRI metrics by Dallaire-Théroux, Caroline, Beheshti, Iman, Potvin, Olivier, Dieumegarde, Louis, Saikali, Stephan, Duchesne, Simon

“…Alzheimer's disease diagnosis requires postmortem visualization of amyloid and tau deposits. As brain atrophy can provide assessment of consequent…”
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Olfactory ensheathing cell tumour: case report and literature review by Darie, Ioana, Riffaud, Laurent, Saïkali, Stéphan, Brassier, Gilles, Hamlat, Abderrahmane

“…Olfactory ensheathing cell tumour (OECT) and olfactory groove schwannoma (OGS) are among the rarest intracranial tumour types that develop within anterior…”
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Subthalamic nucleus modulates social and anxogenic-like behaviors by Reymann, Jean-Michel, Naudet, Florian, Pihan, Morgane, Saïkali, Stephan, Laviolle, Bruno, Bentué-Ferrer, Danièle

“…•In Parkinson's disease, global social maladjustment and anxiety are frequent after subthalamic nucleus (STN) stimulation.•We examine the impact of a STN…”
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