Search Results - "Saifina, Liliya F"
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Applicability of transferable multipole pseudo-atoms for restoring inner-crystal electronic force density fields. Chemical bonding and binding features in the crystal and dimer of 1,3-bis(2-hydroxyethyl)-6-methyluracil
Published in IUCrJ (01-09-2023)“…We considered it timely to test the applicability of transferable multipole pseudo-atoms for restoring inner-crystal electronic force density fields. The…”
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The First 5′-Phosphorylated 1,2,3-Triazolyl Nucleoside Analogues with Uracil and Quinazoline-2,4-Dione Moieties: A Synthesis and Antiviral Evaluation
Published in Molecules (Basel, Switzerland) (21-09-2022)“…A series of 5′-phosphorylated (dialkyl phosphates, diaryl phosphates, phosphoramidates, H-phosphonates, phosphates) 1,2,3-triazolyl nucleoside analogues in…”
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Synthesis and Antiviral Evaluation of Nucleoside Analogues Bearing One Pyrimidine Moiety and Two D-Ribofuranosyl Residues
Published in Molecules (Basel, Switzerland) (16-06-2021)“…A series of 1,2,3-triazolyl nucleoside analogues in which 1,2,3-triazol-4-yl-β-d-ribofuranosyl fragments are attached via polymethylene linkers to both…”
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Synthesis of 1,2,3-triazolyl nucleoside analogues and their antiviral activity
Published in Molecular diversity (01-02-2021)“…Based on the fact that a search for influenza antivirals among nucleoside analogues has drawn very little attention of chemists, the present study reports the…”
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Novel slow-binding reversible acetylcholinesterase inhibitors based on uracil moieties for possible treatment of myasthenia gravis and protection from organophosphate poisoning
Published in European journal of medicinal chemistry (15-01-2023)“…A series of new compounds in which uracil and 3,6-dimethyluracil moieties are bridged with different spacers were prepared and evaluated in vitro for the…”
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Synthesis, antimicrobial activity and cytotoxicity of triphenylphosphonium (TPP) conjugates of 1,2,3-triazolyl nucleoside analogues
Published in Bioorganic chemistry (01-11-2021)“…[Display omitted] •Novel TPP-conjugates of 1,2,3-triazolyl nucleoside analogues were synthesized.•Both antibacterial activity and cytotoxicity against human…”
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Conjugates of nucleobases with triazole-hydroxamic acids for the reactivation of acetylcholinesterase and treatment of delayed neurodegeneration induced by organophosphate poisoning
Published in Bioorganic chemistry (01-12-2023)“…[Display omitted] •Synthesis of conjugates of adenine and uracil derivatives with triazole-hydroxamic acids moieties as uncharged reactivators of…”
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Applicability of transferable multipole pseudo-atoms for restoring inner-crystal electronic force density fields. Chemical bonding and binding features in the crystal and dimer of 1,3-bis(2-hydroxyethyl)-6-methyluracil
Published in IUCrJ (01-09-2023)“…This article accompanies the award of the Struchkov Prize to Robert Fayzullin. It is part of a collection of articles from the IUCr 2023 Congress in Melbourne,…”
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Acetylenyl substituted nucleic bases and their triphenylphosphonium (TPP) conjugates. Unexpected surge in cytotoxicity
Published in Bioorganic chemistry (01-01-2024)Get full text
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Synthesis and antiviral activity of 1,2,3-triazolyl nucleoside analogues with N-acetyl-d-glucosamine residue
Published in Nucleosides, nucleotides & nucleic acids (2023)“…A series of 1,2,3-triazolyl nucleoside analogues bearing N-acetyl-D-glucosamine residue was synthesized by the copper-catalyzed alkyne-azide cycloaddition…”
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On the transfer of theoretical multipole parameters for restoring static electron density and revealing and treating atomic anharmonic motion. Features of chemical bonding in crystals of an isocyanuric acid derivative
Published in Acta crystallographica Section B, Structural science, crystal engineering and materials (01-12-2021)“…The crystal and electronic structure of an isocyanuric acid derivative was studied by high‐resolution single‐crystal X‐ray diffraction within the…”
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X-ray charge density study of the 6-methyluracil derivative in the crystal: Revealing, consequences, and multipole refinement of minor static disorder
Published in Journal of molecular structure (15-03-2021)“…•Electron density distribution in the crystal of 1,6-dimethyl-3-propargyl-2,4-pyrimidinedione, a derivative of 6-methyluracil, was modeled within the…”
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Novel dicationic pyrimidine-based nucleolipid bearing piperidine head groups: Synthesis, aggregation behavior, solubilization capacity and interaction with DNA decamer
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (20-08-2020)“…[Display omitted] Novel dicationic nucleolipid bearing piperidine head groups has been synthesized. Using various physico-chemical methods (tensiometry,…”
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Synthesis of novel 1,2,3-triazolyl nucleoside analogues bearing uracil, 6-methyluracil, 3,6-dimethyluracil, thymine, and quinazoline-2,4-dione moieties
Published in Tetrahedron letters (21-11-2019)“…[Display omitted] •A series of novel 1,2,3-triazolyl pyrimidine nucleoside analogues was synthesized.•The pyrimidine moiety was connected to a triazolyl ring…”
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Triphenylphosphonium (TPP) conjugates of 1,2,3-triazolyl nucleoside analogues. Synthesis, cytotoxicity and antimicrobial activity
Published in Medicinal chemistry research (10-11-2024)Get full text
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