Search Results - "Saidin, Sazuita"
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Epigenome-Wide DNA Methylation Profiling in Colorectal Cancer and Normal Adjacent Colon Using Infinium Human Methylation 450K
Published in Diagnostics (Basel) (14-01-2022)“…The aims were to profile the DNA methylation in colorectal cancer (CRC) and to explore cancer-specific methylation biomarkers. Fifty-four pairs of CRCs and the…”
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Integrated Characterization of MicroRNA and mRNA Transcriptome in Papillary Thyroid Carcinoma
Published in Frontiers in endocrinology (Lausanne) (16-04-2018)“…The incidence rate of papillary thyroid carcinoma (PTC) has rapidly increased in the recent decades, and the microRNA (miRNA) is one of the potential…”
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Deep Small RNA Sequencing of BRAF V600E Mutated Papillary Thyroid Carcinoma With Lymph Node Metastasis
Published in Frontiers in genetics (08-10-2019)Get full text
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Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations
Published in Frontiers in molecular biosciences (14-02-2023)“…The incidences of colorectal cancer (CRC) are continuously increasing in some areas of the world, including Malaysia. In this study, we aimed to characterize…”
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TCGA-My: A Systematic Repository for Systems Biology of Malaysian Colorectal Cancer
Published in Life (Basel, Switzerland) (24-05-2022)“…Colorectal cancer (CRC) ranks second among the most commonly occurring cancers in Malaysia, and unfortunately, its pathobiology remains unknown. CRC…”
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Molecular characterization of serous ovarian carcinoma using a multigene next generation sequencing cancer panel approach
Published in BMC research notes (17-11-2014)“…High grade serous ovarian cancer is one of the poorly characterized malignancies. This study aimed to elucidate the mutational events in Malaysian patients…”
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Epigenome analysis of colorectal cancer: a genome wide approach
Published in Frontiers in pharmacology (2018)“…Abstract only…”
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MicroRNA-200c and microRNA-31 regulate proliferation, colony formation, migration and invasion in serous ovarian cancer
Published in Journal of ovarian research (12-08-2015)“…Serous epithelial ovarian cancer (SEOC) is a highly metastatic disease and its progression has been implicated with microRNAs. This study aimed to identify the…”
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Differential gene expression analysis of papillary thyroid carcinoma reveals important genes for lymph node metastasis
Published in Progress in Microbes and Molecular Biology (17-07-2022)“…Background: Papillary thyroid carcinoma (PTC) is the most prevalent thyroid cancer. We explored the differential gene expression (DEG) of the transcriptional…”
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Validation of immunogenic PASD1 peptides against HLA-A24:02 colorectal cancer
Published in Immunotherapy (01-10-2019)“…Colorectal cancer is the third commonest malignancy in Asia including Malaysia. The immunogenic cancer-testis antigens, which are expressed in a variety of…”
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In-depth characterization of miRNome in papillary thyroid cancer with BRAF V600E mutation
Published in Progress in Microbes and Molecular Biology (18-03-2020)“…MicroRNAs (miRNAs) are small non-coding RNAs, which play a critical regulatory role in papillary thyroid carcinoma (PTC). BRAF V600E is a hotspot mutation…”
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Development of a Semiconductor Sequencing-based Panel for Screening Individuals with Lynch Syndrome
Published in Progress in Microbes and Molecular Biology (31-07-2022)“…Lynch syndrome is a genetic disorder associated with mutations in mismatch repair (MMR) genes that are linked to the development of colorectal cancer…”
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Uncovering the landscape of somatic mutations in Malaysian colorectal cancer patients via whole genome sequencing
Published in Frontiers in pharmacology (2018)“…Abstract only…”
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14
Whole exome sequencing identifies genomic alterations in proximal and distal colorectal cancer
Published in Progress in Microbes and Molecular Biology (30-09-2019)“…Majority of colorectal cancer (CRC) patients are presented with advanced disease at diagnosis, particularly in cases of proximal CRCs. Little is known about…”
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