Search Results - "Said, Neveen"

Roles of SPARC in urothelial carcinogenesis, progression and metastasis by Said, Neveen

“…Secreted Protein Acidic and Rich in Cysteine (SPARC) is a matricellular glycoprotein that is implicated in myriad physiological and pathological conditions…”
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Redox Homeostasis and Metabolism in Cancer: A Complex Mechanism and Potential Targeted Therapeutics by Ghoneum, Alia, Abdulfattah, Ammar Yasser, Warren, Bailey Olivia, Shu, Junjun, Said, Neveen

“…Reactive Oxygen Species or "ROS" encompass several molecules derived from oxygen that can oxidize other molecules and subsequently transition rapidly between…”
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Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARC by John, Bincy, Naczki, Christine, Patel, Chirayu, Ghoneum, Alia, Qasem, Shadi, Salih, Ziyan, Said, Neveen

“…Ovarian cancer (OvCa) exhibits a specific predilection for metastasis to the omentum. Our earlier studies highlighted the tumour-suppressor effect of secreted…”
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Exploring the clinical value of tumor microenvironment in platinum-resistant ovarian cancer by Ghoneum, Alia, Almousa, Sameh, Warren, Bailey, Abdulfattah, Ammar Yasser, Shu, Junjun, Abouelfadl, Hebatullah, Gonzalez, Daniela, Livingston, Christopher, Said, Neveen

“…Platinum resistance in epithelial ovarian cancer (OvCa) is rising at an alarming rate, with recurrence of chemo-resistant high grade serous OvCa (HGSC) in…”
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Spatially resolved metabolomic characterization of muscle invasive bladder cancer by mass spectrometry imaging by Tu, Anqi, Said, Neveen, Muddiman, David C.

“…Introduction Muscle invasive bladder cancer (MIBC) is an advanced stage of bladder cancer which poses a severe threat to life. Cancer development is usually…”
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Secreted Protein Acidic and Rich in Cysteine (SPARC) Mediates Metastatic Dormancy of Prostate Cancer in Bone by Sharma, Sambad, Xing, Fei, Liu, Yin, Wu, Kerui, Said, Neveen, Pochampally, Radhika, Shiozawa, Yusuke, Lin, Hui-Kuan, Balaji, K.C., Watabe, Kounosuke

“…Prostate cancer is known to frequently recur in bone; however, how dormant cells switch its phenotype leading to recurrent tumor remains poorly understood. We…”
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Tumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancer by Said, Neveen, Smith, Steven, Sanchez-Carbayo, Marta, Theodorescu, Dan

“…Many patients with advanced bladder cancer develop lethal metastases to the lung. The vasoconstricting protein endothelin-1 (ET-1) has been implicated in this…”
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Metabolic Plasticity in Ovarian Cancer Stem Cells by Ghoneum, Alia, Gonzalez, Daniela, Abdulfattah, Ammar Yasser, Said, Neveen

“…Ovarian Cancer is the fifth most common cancer in females and remains the most lethal gynecological malignancy as most patients are diagnosed at late stages of…”
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Metabolomic credentialing of murine carcinogen-induced urothelial cancer by Afify, Hesham, Ghoneum, Alia, Almousa, Sameh, Abdulfattah, Ammar Yasser, Warren, Bailey, Langsten, Kendall, Gonzalez, Daniela, Casals, Randy, Bharadwaj, Manish, Kridel, Steven, Said, Neveen

“…Bladder cancer (BCa) is the most common malignancy of the urinary system with increasing incidence, mortality, and limited treatment options. Therefore, it is…”
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Role of tumor microenvironment in the pathobiology of ovarian cancer: Insights and therapeutic opportunities by Ghoneum, Alia, Afify, Hesham, Salih, Ziyan, Kelly, Michael, Said, Neveen

“…Ovarian cancer is the fifth most common cancer affecting women and at present, stands as the most lethal gynecologic malignancy. The poor disease outcome is…”
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Raman chemometric urinalysis (Rametrix) as a screen for bladder cancer by Huttanus, Herbert M, Vu, Tommy, Guruli, Georgi, Tracey, Andrew, Carswell, William, Said, Neveen, Du, Pang, Parkinson, Bing G, Orlando, Giuseppe, Robertson, John L, Senger, Ryan S

“…Bladder cancer (BCA) is relatively common and potentially recurrent/progressive disease. It is also costly to detect, treat, and control. Definitive diagnosis…”
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Loss of SPARC in bladder cancer enhances carcinogenesis and progression by Said, Neveen, Frierson, Henry F, Sanchez-Carbayo, Marta, Brekken, Rolf A, Theodorescu, Dan

“…Secreted protein acidic and rich in cysteine (SPARC) has been implicated in multiple aspects of human cancer. However, its role in bladder carcinogenesis and…”
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RhoGDI2 suppresses bladder cancer metastasis via reduction of inflammation in the tumor microenvironment by Said, Neveen, Theodorescu, Dan

“…Low expression of RhoGDI2 is associated with poor outcome in cancer patients. In animal models, RhoGDI2 suppresses lung metastasis by reducing the expression…”
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Loss of SPARC in bladder cancer enhances carcinogenesis and progression by Said, Neveen, Frierson, Henry F., Sanchez-Carbayo, Marta, Brekken, Rolf A., Theodorescu, Dan

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Secreted Protein Acidic and Rich in Cysteine (SPARC) Inhibits Integrin-Mediated Adhesion and Growth Factor-Dependent Survival Signaling in Ovarian Cancer by Said, Neveen, Najwer, Ida, Motamed, Kouros

“…The matricellular glycoprotein SPARC (secreted protein acidic and rich in cysteine) has been accorded major roles in regulation of cell adhesion and…”
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Absence of Host-Secreted Protein Acidic and Rich in Cysteine (SPARC) Augments Peritoneal Ovarian Carcinomatosis by Said, Neveen, Motamed, Kouros

“…The matricellular glycoprotein SPARC (secreted protein acidic and rich in cysteine) possesses multifaceted roles in modulation of cell-matrix interactions, as…”
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Pathways of metastasis suppression in bladder cancer by Said, Neveen, Theodorescu, Dan

“…Despite the recent advances in the diagnosis of bladder cancer, recurrence after surgical intervention for muscle invasive disease is still problematic as…”
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SPARC Ameliorates Ovarian Cancer-Associated Inflammation by Said, Neveen A., Elmarakby, Ahmed A., Imig, John D., Fulton, David J., Motamed, Kouros

“…We have recently identified that the role of secreted protein acidic and rich in cysteine (SPARC) in amelioration of peritoneal ovarian carcinomatosis is…”
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Lack of Rev7 function results in development of tubulostromal adenomas in mouse ovary by Abbasi, Abdolrahim, Khalaj, Maryam, Akiyama, Kouyou, Mukai, Yoshiyuki, Matsumoto, Hirokazu, Acosta, Tomas J., Said, Neveen, Yoshida, Midori, Kunieda, Tetsuo

“…•Rev7 mutant mouse lacks oocyte and develops tubulostromal adenomas in ovary.•Rev7 mutant mouse shows significantly increased blood gonadotropin level.•Cells…”
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Aggressiveness Niche: Can It Be the Foster Ground for Cancer Metastasis Precursors? by ElShamy, Wael M., Said, Neveen, Sinha, Abhilasha

“…The relationship between tumor initiation and tumor progression can follow a linear projection in which all tumor cells are equally endowed with the ability to…”
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