Search Results - "Said, Musa A."

Potential COVID-19 Drug Candidates Based on Diazinyl-Thiazol-Imine Moieties: Synthesis and Greener Pastures Biological Study by Abu-Melha, Sraa, Edrees, Mastoura Mohamed, Said, Musa A, Riyadh, Sayed M, Al-Kaff, Nadia S, Gomha, Sobhi M

“…A novel series of 1-aryl- -[4-phenyl-5-(arylazo)thiazol-2-yl)methanimines has been synthesized via the condensation of 2-amino-4-phenyl-5-arylazothiazole with…”
Get full text

Synthesis and greener pastures biological study of bis-thiadiazoles as potential Covid-19 drug candidates by Said, Musa A., Riyadh, Sayed M., Al-Kaff, Nadia S., Nayl, A.A., Khalil, Khaled D., Bräse, Stefan, Gomha, Sobhi M.

“…A novel series of bis- (Abdelhamid et al., 2017; Banerjee et al., 2018; Bharanidharan et al., 2022)thiadiazoles was synthesized from the reaction of precursor…”
Get full text

The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations by Musa, Arafa, Ihmaid, Saleh K., Hughes, David L., Said, Musa A., Abulkhair, Hamada S., El-Ghorab, Ahmed H., Abdelgawad, Mohamed A., Shalaby, Khaled, Shaker, Mohamed E., Alharbi, Khalid Saad, Alotaibi, Nasser Hadal, Kays, Deborah L., Taylor, Laurence J., Parambi, Della Grace Thomas, Alzarea, Sami I., Al-Karmalawy, Ahmed A., Ahmed, Hany E. A., El-Agrody, Ahmed M.

“…Treatment options for the management of breast cancer are still inadequate. This inadequacy is attributed to the lack of effective targeted medications, often…”
Get full text

A possible potential COVID-19 drug candidate: Diethyl 2-(2-(2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetyl)hydrazono)malonate: Docking of disordered independent molecules of a novel crystal structure, HSA/DFT/XRD and cytotoxicity by Missioui, Mohcine, Said, Musa A., Demirtaş, Güneş, Mague, Joel T., Al-Sulami, Ahlam, Al-Kaff, Nadia S., Ramli, Youssef

“…This study reports the synthesis, characterization and importance of a novel diethyl 2-(2-(2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetyl)hydrazono)malonate…”
Get full text

New 1,2,3-Triazole Scaffold Schiff Bases as Potential Anti-COVID-19: Design, Synthesis, DFT-Molecular Docking, and Cytotoxicity Aspects by Said, Musa A., Khan, Daoud J. O., Al-blewi, Fawzia F., Al-Kaff, Nadia S., Ali, Adeeb A., Rezki, Nadjet, Aouad, Mohamed Reda, Hagar, Mohamed

“…Schiff bases encompassing a 1,2,3-triazole motif were synthesized using an efficient multi-step synthesis. The formations of targeted Schiff base ligands were…”
Get full text

Microwave-Assisted Synthesis of Mono- and Disubstituted 4-Hydroxyacetophenone Derivatives via Mannich Reaction: Synthesis, XRD and HS-Analysis by Aljohani, Ghadah, Said, Musa A, Lentz, Dieter, Basar, Norazah, Albar, Arwa, Alraqa, Shaya Y, Ali, Adeeb Al-Sheikh

“…An efficient microwave-assisted one-step synthetic route toward Mannich bases is developed from 4-hydroxyacetophenone and different secondary amines in…”
Get full text

Crystal structure of a 1,1,2,2-tetrachloroethane-solvated hydrazinecarbothioamide compound by Riyadh, Sayed, Hughes, David L., Said, Musa A

“…The title compound, [(1-{4-[2-(2,4-dihydroxyphenyl)diazen-1-yl]phenyl}ethylidene)amino]thiourea, 1,1,2,2-tetrachloroethane monosolvate, C 15 H 15 N 5 O 2 S·C 2…”
Get full text

Easy coordinate geometry indexes, τ4 and τ5 and HSA study for unsymmetrical Pd(II), Fe(II), Zn(II), Mn(II), Cu(II) and VO(IV) complexes of a tetradentate ligand: Synthesis, characterization, properties, and antioxidant activities by Said, Musa A., Al-unizi, Anwar, Al-Mamary, Mohammed, Alzahrani, Seraj, Lentz, Dieter

“…[Display omitted] •Six new monomeric Schiff base complexes of [M = Pd (1), Zn (2), Cu (3), Fe (4), Mn (6) and V(O) (7)] have been synthesized.•Coordinate…”
Get full text

Synthesis and crystal structure of a new pyridinium bromide salt: 4-methyl-1-(3-phen-oxy-prop-yl)pyridinium bromide by Said, Musa A, Aouad, Mohamed R, Hughes, David L, Almehmadi, Meshal A, Messali, Mouslim

“…In the cation of the title mol-ecular salt, C H NO ·Br , the pyridinium and phenyl rings are inclined to one another by 11.80 (8)°. In the crystal, the Br…”
Get full text

First COVID‐19 molecular docking with a chalcone‐based compound: synthesis, single‐crystal structure and Hirshfeld surface analysis study by Alsafi, Mona A., Hughes, David L., Said, Musa A.

“…The first example of molecular docking of the SARS‐CoV‐2 main protease for COVID‐19 [Mpro, Protein Data Bank (PDB) code 7BQY] by a chalcone‐based ligand,…”
Get full text

Crystal structure of (E)-1-{2-[(5,5-dimethyl-1,3,2-dioxaphosphinan-2-yl)-oxy]naphthalen-1-yl}-N-(4-fluoro-phen-yl)methanimine by Said, Musa A, Al Belewi, Bayan L, Hughes, David L

“…In the title compound, C22H21FNO3P, a 1,3,2-dioxaphosphinan-2-yloxy derivative, three O atoms are bonded in a trigonal-pyramidal manner to the P atom. The…”
Get full text

Innovation of Fe(III), Ni(II), and Pd(II) complexes derived from benzothiazole imidazolidin‐4‐ol ligand: Geometrical elucidation, theoretical calculation, and pharmaceutical studies by Abu‐Dief, Ahmed M., Said, Musa A., Elhady, Omar, Al‐Abdulkarim, Hessah A., Alzahrani, Seraj, Eskander, Thomas Nady A., El‐Remaily, Mahmoud Abd El Aleem Ali Ali

“…The synthesis of a simple, highly tunable, and effective BSI ligand, 2‐(benzothiazol‐2‐ylimino)‐2,3‐dihydro‐1H‐imidazol‐4‐ol, was presented. Three new…”
Get full text

Design, structural inspection of some new metal chelates based on benzothiazol- pyrimidin-2-ylidene ligand: Biomedical studies and molecular docking approach by Abu-Dief, Ahmed M., Said, Musa A., Elhady, O., Alzahrani, Seraj, Aljohani, Faizah S., Eskander, Thomas Nady A., Ali El-Remaily, Mahmoud Abd El Aleem Ali

Get full text

Newly synthesized Bis-Hydrazono[1,3,4] thiadiazoles as Anti-Alzheimer’s Agents: Greener past and In-Vitro acetylcholinesterase inhibition assay investigations by Alharbi, Reem A.K., Riyadh, Sayed M., Al-Kaff, Nadia S., Said, Musa A.

“…[Display omitted] The designed and synthesized multifunctional properties of bis-hydrazono[1,3,4]thiadiazoles became important for developing an efficient…”
Get full text

Greener pastures in evaluating antidiabetic drug for a quinoxaline Derivative: Synthesis, Characterization, Molecular Docking, in vitro and HSA/DFT/XRD studies by Missioui, Mohcine, Mortada, Salma, Guerrab, Walid, Demirtaş, Güneş, Mague, Joel T., Ansar, M'hammed, El Abbes Faouzi, My, Essassi, E.M., Mehdar, Yassin T.H., Aljohani, Faizah S., Said, Musa A., Ramli, Youssef

“…The physicochemical, pharmacokinetic and toxicological properties of MOQTA have been evaluated. [Display omitted] •A new quinoxaline containing triazole MOQTA…”
Get full text

Synthesis and XRD of neutral NiL complex using unsymmetrical ONNO tetradentate schiff base: Hirschfeld, spectral, DFT and thermal analysis by Said, Musa A., Qasem, Hamza A., Alzahrani, Seraj O., Zarrouk, Abdelkader, Warad, Ismail

“…The unsymmetrical tetradentate ONNO Schiff base 6,6'-((1E,1'E)-((2-methylpropane-1,2-diyl)bis(azanylylidene))bis(methanylylidene))bis(2,4-di-tert-butylphenol)…”
Get full text

Novel 1,2,3‐Triazole Derivatives as Potential Inhibitors against Covid‐19 Main Protease: Synthesis, Characterization, Molecular Docking and DFT Studies by Aouad, Mohamed Reda, Khan, Daoud J. O., Said, Musa A., Al‐Kaff, Nadia S., Rezki, Nadjet, Ali, Adeeb A., Bouqellah, Nahla, Hagar, Mohamed

“…The highly contagious nature of Covid‐19 attracted us to this challenging area of research, mainly because the disease is spreading very fast and until now, no…”
Get full text

Cu(II)(PhOMe-Salophen) Complex: Greener Pasture Biological Study, XRD/HAS Interactions, and MEP by Manas Bandyopadhyay, Sengupta, Utsav, Periyasamy, Muthaimanoj, Mukhopadhyay, Sudipta, Hasija, Avantika, Chopra, Deepak, Özdemir, Namık, Said, Musa A., Bera, Mrinal K.

“…PhOMe-salophen ( 1b ) (salophen is N , N -bis(salycilidene)-1,2-phenylenediamine with two tert- butyl on each ring) and Cu(II) complex with PhOMe-salophen ( 1c…”
Get full text

Synthesis of Silver(I) Complexes Containing 3‑Oxo-3-phenyl-2-(2-phenylhydrazono)propanal-Based Ligands as a Multifunction Platform for Antimicrobial and Optoelectronic Applications by Al-Sulami, Ahlam I., Basha, Maram T., AlGhamdi, Huda A., S. Albalawi, Sarah, M. Al-Zaydi, Khadijah, Said, Musa A.

“…Toward multifunctionality, including antimicrobial and optoelectronic applications, herein, we reported the synthesis of a novel Ag­(I) complex with…”
Get full text

Design, synthesis, and greener pasture biological assessment of a novel nucleoside: 1-(α-D-ribofuranosyl)-6,7-difluoro-2-methyl-4-quinazolinone as an inhibitor of COVID-19 and Alzheimer's disease by BREAK, LAILA M., GOBOURI, ADIL A., AL-HARTHI, WAFA S., HAGAR, MOHAMED, ALKAFF, NADIA S., SAID, MUSA A.

“…Synthesis of a new fluorinated nucleoside of 6,7-difluoro-2-methyl-4-quinazolinone was described. 2-Amino-4,5-difluorobenzoic acid 1 reacts with (CH 3 CO) 2 O…”
Get full text