Search Results - "Said, Jongo"

The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes by Hill, Danika L, Pierson, Wim, Bolland, Daniel J, Mkindi, Catherine, Carr, Edward J, Wang, Jiong, Houard, Sophie, Wingett, Steven W, Audran, Regine, Wallin, Elizabeth F, Jongo, Said A, Kamaka, Kassim, Zand, Martin, Spertini, Francois, Daubenberger, Claudia, Corcoran, Anne E, Linterman, Michelle A

“…The generation of protective humoral immunity after vaccination relies on the productive interaction between antigen-specific B cells and T follicular helper…”
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Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial by Oneko, Martina, Steinhardt, Laura C., Yego, Reuben, Wiegand, Ryan E., Swanson, Phillip A., KC, Natasha, Akach, Dorcas, Sang, Tony, Gutman, Julie R., Nzuu, Elizabeth L., Dungani, Allan, Kim Lee Sim, B., Oloo, Paul Ndaya, Otieno, Kephas, Bii, Dennis K., Billingsley, Peter F., James, Eric R., Kariuki, Simon, Samuels, Aaron M., Jongo, Said, Chebore, Winnie, Abdulla, Salim, Daubenberger, Claudia, Mpina, Maxmillian, Styers, David, Potter, Gail E., Abarbanell, Ginnie, Richie, Thomas L., Hoffman, Stephen L., Seder, Robert A.

“…The radiation-attenuated Plasmodium falciparum sporozoite (PfSPZ) vaccine provides protection against P. falciparum infection in malaria-naïve adults…”
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Increase of Dose Associated With Decrease in Protection Against Controlled Human Malaria Infection by PfSPZ Vaccine in Tanzanian Adults by Jongo, Said A, Church, L W Preston, Mtoro, Ali T, Schindler, Tobias, Chakravarty, Sumana, Ruben, Adam J, Swanson, Phillip A, Kassim, Kamaka R, Mpina, Maximillian, Tumbo, Anneth-Mwasi, Milando, Florence A, Qassim, Munira, Juma, Omar A, Bakari, Bakari M, Simon, Beatus, James, Eric R, Abebe, Yonas, KC, Natasha, Saverino, Elizabeth, Fink, Martina, Cosi, Glenda, Gondwe, Linda, Studer, Fabian, Styers, David, Seder, Robert A, Billingsley, Peter F, Daubenberger, Claudia, Sim, B Kim Lee, Tanner, Marcel, Richie, Thomas L, Abdulla, Salim, Hoffman, Stephen L

“…Abstract Background A vaccine would be an ideal tool for reducing malaria’s impact. PfSPZ Vaccine (radiation attenuated, aseptic, purified, cryopreserved…”
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Nanotechnological immunoassay for rapid label-free analysis of candidate malaria vaccines by Brunetti, Giulio, Padovani, Francesco, De Pastina, Annalisa, Rotella, Chiara, Monahan, Amy, Hoffman, Stephen L, Jongo, Said A, Abdulla, Salim, Corradin, Giampietro, Pluschke, Gerd, Daubenberger, Claudia, Hegner, Martin

“…Malaria is a life-threatening epidemic disease with half of the world's population at risk. Although its incidence rate has fallen since 2010, this ratio…”
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Pre-vaccination monocyte-to-lymphocyte ratio as a biomarker for the efficacy of malaria candidate vaccines: A subgroup analysis of pooled clinical trial data by Nyandele, Jane Paula, Kibondo, Ummi Abdul, Issa, Fatuma, Van Geertruyden, Jean Pierre, Warimwe, George, Jongo, Said, Abdulla, Salim, Olotu, Ally

“…Background Pre-vaccination monocyte-to-lymphocyte ratio was previously suggested as a marker for malaria vaccine effectiveness. We investigated the potential…”
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Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults by Camponovo, Flavia, Campo, Joseph J, Le, Timothy Q, Oberai, Amit, Hung, Christopher, Pablo, Jozelyn V, Teng, Andy A, Liang, Xiaowu, Sim, B Kim Lee, Jongo, Said, Abdulla, Salim, Tanner, Marcel, Hoffman, Stephen L, Daubenberger, Claudia, Penny, Melissa A

“…Tanzanian adult male volunteers were immunized by direct venous inoculation with radiation-attenuated, aseptic, purified, cryopreserved (Pf) sporozoites (PfSPZ…”
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Safety and Differential Antibody and T-Cell Responses to the Plasmodium falciparum Sporozoite Malaria Vaccine, PfSPZ Vaccine, by Age in Tanzanian Adults, Adolescents, Children, and Infants by Jongo, Said A, Church, L W Preston, Mtoro, Ali T, Chakravarty, Sumana, Ruben, Adam J, Swanson, Phillip A, Kassim, Kamaka R, Mpina, Maximillian, Tumbo, Anneth-Mwasi, Milando, Florence A, Qassim, Munira, Juma, Omar A, Bakari, Bakari M, Simon, Beatus, James, Eric R, Abebe, Yonas, Kc, Natasha, Saverino, Elizabeth, Gondwe, Linda, Studer, Fabian, Fink, Martina, Cosi, Glenda, El-Khorazaty, Jill, Styers, David, Seder, Robert A, Schindler, Tobias, Billingsley, Peter F, Daubenberger, Claudia, Sim, B Kim Lee, Tanner, Marcel, Richie, Thomas L, Abdulla, Salim, Hoffman, Stephen L

“…In 2016, there were more cases and deaths caused by malaria globally than in 2015. An effective vaccine would be an ideal additional tool for reducing…”
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Pilot deployment of a community health care worker in distributing and offering the COVID-19 AgRDT in Tanzania by Mrisho, Mwifadhi, Mwangoka, Grace, Ali, Ali M., Mkopi, Abdallah, Mahende, Muhidin K., Temu, Silas, Msuya, Hajirani M., Kazyoba, Paul E., Abdallah, Gumi, Mihayo, Michael, Juma, Omar, Hamad, Ali, Jongo, Said, Lweno, Omar, Tumbo, Anneth, Mswata, Sarah, Kassim, Kamaka R., Kishimba, Rogath, Haruna, Hussein, Kassa, Hellen, Kapologwe, Ntuli, Rashid, Mohammed, Abdulla, Salim

“…A pilot implementation of the rapid diagnostic test program was performed to collect evidence of the feasibility, acceptability, and uptake of the COVID-19…”
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Population Pharmacokinetics of Antimalarial Naphthoquine in Combination with Artemisinin in Tanzanian Children and Adults: Dose Optimization by Ali, Ali Mohamed, Gausi, Kamunkhwala, Jongo, Said A, Kassim, Kamaka R, Mkindi, Catherine, Simon, Beatus, Mtoro, Ali T, Juma, Omar A, Lweno, Omar N, Gwandu, Conrad H, Bakari, Bakari M, Mbaga, Thabiti A, Milando, Florence A, Hamad, Ali, Shekalaghe, Seif A, Abdulla, Salim, Denti, Paolo, Penny, Melissa A

“…The combination antimalarial therapy of artemisinin-naphthoquine (ART-NQ) was developed as a single-dose therapy, aiming to improve adherence relative to the…”
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Understanding Sociodemographic Factors and Reasons Associated with COVID-19 Vaccination Hesitance among Adults in Tanzania: A Mixed-Method Approach by Msuya, Hajirani M., Mrisho, Gumi A., Mkopi, Abdallah, Mrisho, Mwifadhi, Lweno, Omar N., Ali, Ali M., Said, Ali H., Mihayo, Michael G., Mswata, Sara S., Tumbo, Anneth M., Mhalu, Grace, Jongo, Said A., Kassim, Kamaka R., Nyaulingo, Gloria D., Temu, Silas G., Kazyoba, Paul E., Haruna, Hussein, Kishimba, Rogath, Kassa, Hellen, Mwangoka, Grace W., Abdulla, Salim

“…Although studies on COVID-19 vaccine hesitancy are being undertaken widely worldwide, there is limited evidence in Tanzania. This study aims to assess the…”
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Motivations and barriers for healthy participants to participate in herbal remedy clinical trial in Tanzania: A qualitative study based on the theory of planned behaviour by Kassimu, Kamaka R, Milando, Florence A, Omolo, Justin J, Nyaulingo, Gloria, Mbarak, Hussein, Mohamed, Latipha, Rashid, Ramla, Ahmed, Saumu, Rashid, Mohammed, Abdallah, Gumi, Mbaga, Thabit, Issa, Fatuma, Lweno, Omar, Balige, Neema, Mwalimu, Bakari, Hamad, Ali, Olotu, Ally, Jongo, Said, Ngasala, Billy, Abdulla, Salim

“…The success of any randomized clinical trial relies on the willingness of people to be recruited in the trial. However, 90% of all clinical trials worldwide…”
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The Candidate Blood-stage Malaria Vaccine P27A Induces a Robust Humoral Response in a Fast Track to the Field Phase 1 Trial in Exposed and Nonexposed Volunteers by Steiner-Monard, Viviane, Kamaka, Kassim, Karoui, Olfa, Roethlisberger, Samuel, Audran, Régine, Daubenberger, Claudia, Fayet-Mello, Aurélie, Erdmann-Voisin, Aude, Felger, Ingrid, Geiger, Kristina, Govender, Lerisa, Houard, Sophie, Huber, Eric, Mayor, Carole, Mkindi, Catherine, Portevin, Damien, Rusch, Sebastian, Schmidlin, Sandro, Tiendrebeogo, Regis W, Theisen, Michael, Thierry, Anne-Christine, Vallotton, Laure, Corradin, Giampietro, Leroy, Odile, Abdulla, Salim, Shekalaghe, Seif, Genton, Blaise, Spertini, François, Jongo, Said A

“…Abstract Background P27A is an unstructured 104mer synthetic peptide from Plasmodium falciparum trophozoite exported protein 1 (TEX1), the target of human…”
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A multiplex qPCR approach for detection of pfhrp2 and pfhrp3 gene deletions in multiple strain infections of Plasmodium falciparum by Schindler, Tobias, Deal, Anna C., Fink, Martina, Guirou, Etienne, Moser, Kara A., Mwakasungula, Solomon M., Mihayo, Michael G., Jongo, Said A., Chaki, Prosper P., Abdulla, Salim, Valverde, Paulo C. Manrique, Torres, Katherine, Bijeri, Jose R., Silva, Joana C., Hoffman, Stephen L., Gamboa, Dionicia, Tanner, Marcel, Daubenberger, Claudia

“…The rapid and accurate diagnosis of Plasmodium falciparum malaria infection is an essential factor in malaria control. Currently, malaria diagnosis in the…”
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Early whole blood transcriptional responses to radiation-attenuated Plasmodium falciparum sporozoite vaccination in malaria naïve and malaria pre-exposed adult volunteers by Duffy, Fergal J, Du, Ying, Carnes, Jason, Epstein, Judith E, Hoffman, Stephen L, Abdulla, Salim, Jongo, Said, Mpina, Maxmillian, Daubenberger, Claudia, Aitchison, John D, Stuart, Ken

“…Background Vaccination with radiation-attenuated Plasmodium falciparum sporozoites is known to induce protective immunity. However, the mechanisms underlying…”
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Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection of low-density Plasmodium falciparum infections during a controlled human malaria infection study in Equatorial Guinea by Mpina, Maxmillian, Stabler, Thomas C, Schindler, Tobias, Raso, Jose, Deal, Anna, Acuche Pupu, Ludmila, Nyakarungu, Elizabeth, Del Carmen Ovono Davis, Maria, Urbano, Vicente, Mtoro, Ali, Hamad, Ali, Lopez, Maria Silvia A, Pasialo, Beltran, Eyang, Marta Alene Owono, Rivas, Matilde Riloha, Falla, Carlos Cortes, García, Guillermo A, Momo, Juan Carlos, Chuquiyauri, Raul, Saverino, Elizabeth, Preston Church, L W, Kim Lee Sim, B, Manguire, Bonifacio, Tanner, Marcel, Maas, Carl, Abdulla, Salim, Billingsley, Peter F, Hoffman, Stephen L, Jongo, Said, Richie, Thomas L, Daubenberger, Claudia A

“…Progress towards malaria elimination has stagnated, partly because infections persisting at low parasite densities comprise a large reservoir contributing to…”
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Molecular malaria surveillance using a novel protocol for extraction and analysis of nucleic acids retained on used rapid diagnostic tests by Guirou, Etienne A., Schindler, Tobias, Hosch, Salome, Donfack, Olivier Tresor, Yoboue, Charlene Aya, Krähenbühl, Silvan, Deal, Anna, Cosi, Glenda, Gondwe, Linda, Mwangoka, Grace, Masuki, Heavenlight, Salim, Nahya, Mpina, Maxmillian, Said, Jongo, Abdulla, Salim, Hoffman, Stephen L., Nlavo, Bonifacio Manguire, Maas, Carl, Falla, Carlos Cortes, Phiri, Wonder P., Garcia, Guillermo A., Tanner, Marcel, Daubenberger, Claudia

“…The use of malaria rapid diagnostic tests (RDTs) as a source for nucleic acids that can be analyzed via nucleic acid amplification techniques has several…”
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Assessment of the WHO non-communicable diseases kit for humanitarian emergencies in South Sudan: a retrospective, prospective, observational study by Alani, Ahmad Hecham, Miller, Laura, Darji, Bhavika, Waweru, Isaac, Atwiine, Aston Benjamin, Tonelli, Marcello, Mogga, Joseph Lou Kenyi, Adams, Ali, Ndinda, Lilian, Jongo, Said, Kiapi, Lilian

“…The WHO Non-Communicable Diseases Kit (NCDK) was developed to support care for non-communicable diseases (NCDs) in humanitarian settings. Targeting primary…”
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Two cases of long-lasting, sub-microscopic Plasmodium malariae infections in adults from coastal Tanzania by Schindler, Tobias, Jongo, Said, Studer, Fabian, Mpina, Maximilian, Mwangoka, Grace, Mswata, Sarah, Ramadhani, Kamaka, Sax, Julian, Church, L W Preston, Richie, Thomas L, Tanner, Marcel, Hoffman, Stephen L, Abdulla, Salim, Daubenberger, Claudia

“…Malaria is endemic in Tanzania with majority of clinical cases caused by Plasmodium falciparum. Additionally, Plasmodium malariae and Plasmodium ovale spp. are…”
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Role of human Pegivirus infections in whole Plasmodium falciparum sporozoite vaccination and controlled human malaria infection in African volunteers by Tumbo, Anneth-Mwasi, Schindler, Tobias, Dangy, Jean-Pierre, Orlova-Fink, Nina, Bieri, Jose Raso, Mpina, Maximillian, Milando, Florence A, Juma, Omar, Hamad, Ali, Nyakarungu, Elizabeth, Chemba, Mwajuma, Mtoro, Ali, Ramadhan, Kamaka, Olotu, Ally, Makweba, Damas, Mgaya, Stephen, Stuart, Kenneth, Perreau, Matthieu, Stapleton, Jack T, Jongo, Said, Hoffman, Stephen L, Tanner, Marcel, Abdulla, Salim, Daubenberger, Claudia

“…Diverse vaccination outcomes and protection levels among different populations pose a serious challenge to the development of an effective malaria vaccine…”
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Safety and tolerability of an antimalarial herbal remedy in healthy volunteers: An open-label, single-arm, dose-escalation study on 'Maytenus senegalensis' in Tanzania by Kassimu, Kamaka, Milando, Florence, Omolo, Justin, Mdemu, Abel, Nyaulingo, Gloria, Mbarak, Hussein, Mohamed, Latipha, Rashid, Ramla, Ahmed, Saumu, Rashid, Mohammed, Msami, Hania, Damiano, David, Simon, Beatus, Mbaga, Thabit, Issa, Fatuma, Lweno, Omar, Balige, Neema, Hassan, Omary, Mwalimu, Bakari, Hamad, Ali, Olotu, Ally, Mårtensson, Andreas, Machumi, Francis, Jongo, Said, Ngasala, Billy, Abdulla, Salim

“…Background: Though 'Maytenus senegalensis' is one of the medicinal plants widely used in traditional medicine to treat infectious and inflammatory diseases in…”
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