Search Results - "Said, Iskander"
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1
The Structure of Simple Satellite Variation in the Human Genome and Its Correlation With Centromere Ancestry
Published in Genome biology and evolution (05-08-2024)“…Abstract Although repetitive DNA forms much of the human genome, its study is challenging due to limitations in assembly and alignment of repetitive…”
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Journal Article -
2
Multiple stages of evolutionary change in anthrax toxin receptor expression in humans
Published in Nature communications (15-11-2021)“…The advent of animal husbandry and hunting increased human exposure to zoonotic pathogens. To understand how a zoonotic disease may have influenced human…”
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Journal Article -
3
Linked genetic variation and not genome structure causes widespread differential expression associated with chromosomal inversions
Published in Proceedings of the National Academy of Sciences - PNAS (22-05-2018)“…Chromosomal inversions are widely thought to be favored by natural selection because they suppress recombination between alleles that have higher fitness on…”
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Journal Article -
4
The Population Genetic Variation of Interspersed and Tandem Repeats
Published 01-01-2023“…Despite making up large and essential portions of eukaryotic genomes repeat DNA has largely eluded study due to limitations in alignment and assembly of Next…”
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Dissertation -
5
Patterns of piRNA Regulation in Drosophila Revealed through Transposable Element Clade Inference
Published in Molecular biology and evolution (07-01-2022)“…Abstract Transposable elements (TEs) are self-replicating “genetic parasites” ubiquitous to eukaryotic genomes. In addition to conflict between TEs and their…”
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Journal Article -
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Fine-Mapping Complex Inversion Breakpoints and Investigating Somatic Pairing in the Anopheles gambiae Species Complex Using Proximity-Ligation Sequencing
Published in Genetics (Austin) (01-12-2019)“…Chromosomal inversions are fundamental drivers of genome evolution. In the main Afrotropical malaria vector species, belonging to the species complex,…”
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Journal Article -
7
Sex-linked gene traffic underlies the acquisition of sexually dimorphic UV color vision in Heliconius butterflies
Published in Proceedings of the National Academy of Sciences - PNAS (15-08-2023)“…The acquisition of novel sexually dimorphic traits poses an evolutionary puzzle: How do new traits arise and become sex-limited? Recently acquired color…”
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Journal Article -
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Fine-Mapping Complex Inversion Breakpoints and Investigating Somatic Pairing in the Anopheles gambiae Species Complex Using Proximity-Ligation Sequencing
Published in Genetics (Austin) (01-12-2019)“…In this work, Corbett-Detig et al. use proximity-ligation sequencing (Hi-C) of several Anopheles gambiae and A. coluzzii inversionbearing individuals to detect…”
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Journal Article -
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Fine-Mapping Complex Inversion Breakpoints and Investigating Somatic Pairing in the Anopheles gambiae Species Complex Using Proximity-Ligation Sequencing
Published in Genetics (Austin) (01-12-2019)“…In this work, Corbett-Detig et al. use proximity-ligation sequencing (Hi-C) of several Anopheles gambiae and A. coluzzii inversionbearing individuals to detect…”
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Journal Article