Search Results - "Saib, Ali"
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Suppression of HIV-1 replication by microRNA effectors
Published in Retrovirology (09-03-2009)“…The rate of HIV-1 gene expression is a key step that determines the kinetics of virus spread and AIDS progression. Viral entry and gene expression were…”
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2
The Antiretroviral Activity of APOBEC3 Is Inhibited by the Foamy Virus Accessory Bet Protein
Published in Proceedings of the National Academy of Sciences - PNAS (31-05-2005)“…Genome hypermutation of different orthoretroviruses by cellular cytidine deaminases of the APOBEC3 family during reverse transcription has recently been…”
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3
Simian foamy virus transmission from apes to humans, rural Cameroon
Published in Emerging infectious diseases (01-09-2007)“…Simian virus infections of humans are an increasing public health concern. Simian foamy virus (SFV) infections have been reported in persons occupationally…”
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4
Cellular MicroRNA Mediates Antiviral Defense in Human Cells
Published in Science (American Association for the Advancement of Science) (22-04-2005)“…In eukaryotes, 21- to 24-nucleotide-long RNAs engage in sequence-specific interactions that inhibit gene expression by RNA silencing. This process has…”
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5
JASSA: a comprehensive tool for prediction of SUMOylation sites and SIMs
Published in Bioinformatics (01-11-2015)“…Post-translational modification by the Small Ubiquitin-like Modifier (SUMO) proteins, a process termed SUMOylation, is involved in many fundamental cellular…”
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6
Endogenous retroviruses: Thierry Heidmann wins the 2009 Retrovirology prize
Published in Retrovirology (01-12-2009)“…Thierry Heidmann wins the 2009 Retrovirology prize…”
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7
Two distinct variants of simian foamy virus in naturally infected mandrills (Mandrillus sphinx) and cross-species transmission to humans
Published in Retrovirology (14-12-2010)“…Each of the pathogenic human retroviruses (HIV-1/2 and HTLV-1) has a nonhuman primate counterpart, and the presence of these retroviruses in humans results…”
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8
TRIM family proteins: retroviral restriction and antiviral defence
Published in Nature reviews. Microbiology (01-10-2005)“…Members of the tripartite motif (TRIM) protein family are involved in various cellular processes, including cell proliferation, differentiation, development,…”
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9
SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells
Published in Nature communications (28-07-2021)“…SAMHD1 is a cellular triphosphohydrolase (dNTPase) proposed to inhibit HIV-1 reverse transcription in non-cycling immune cells by limiting the supply of the…”
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10
Modes of transmission and genetic diversity of foamy viruses in a Macaca tonkeana colony
Published in Retrovirology (11-04-2006)“…Foamy viruses are exogenous complex retroviruses that are highly endemic in several animal species, including monkeys and apes, where they cause persistent…”
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11
An RNA polymerase III subunit determines sites of retrotransposon integration
Published in Science (American Association for the Advancement of Science) (01-05-2015)“…Mobile genetic elements are ubiquitous. Their integration site influences genome stability and gene expression. The Ty1 retrotransposon of the yeast…”
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12
Integrase and integration: biochemical activities of HIV-1 integrase
Published in Retrovirology (17-12-2008)“…Integration of retroviral DNA is an obligatory step of retrovirus replication because proviral DNA is the template for productive infection. Integrase, a…”
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13
Characterization of reemerging chikungunya virus
Published in PLoS pathogens (01-06-2007)“…An unprecedented epidemic of chikungunya virus (CHIKV) infection recently started in countries of the Indian Ocean area, causing an acute and painful syndrome…”
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14
Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage
Published in Retrovirology (21-11-2013)“…LEDGF/p75 (LEDGF) is the main cellular cofactor of HIV-1 integrase (IN). It acts as a tethering factor for IN, and targets the integration of HIV in actively…”
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15
Cross-Species Transmission of Simian Foamy Virus to Humans in Rural Gabon, Central Africa
Published in Journal of Virology (01-01-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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16
Restriction of Foamy Viruses by APOBEC Cytidine Deaminases
Published in Journal of Virology (01-01-2006)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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17
HIV-1 integrase SUMOylation and viral replication
Published in Retrovirology (03-10-2011)Get full text
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18
Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration
Published in The Journal of biological chemistry (20-04-2018)“…Recently, a new class of HIV-1 integrase (IN) inhibitors with a dual mode of action, called IN-LEDGF/p75 allosteric inhibitors (INLAIs), was described…”
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19
Early steps of retrovirus replicative cycle
Published in Retrovirology (14-05-2004)“…During the last two decades, the profusion of HIV research due to the urge to identify new therapeutic targets has led to a wealth of information on the…”
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20
Comparative Proteomic Analysis of HIV-1 Particles Reveals a Role for Ezrin and EHD4 in the Nef-Dependent Increase of Virus Infectivity
Published in Journal of Virology (01-04-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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