Search Results - "Saičić, Radomir N"

A study towards the synthesis of (-)-atrop-abyssomicin C core by Saicic, Radomir, Trmcic, Milena

“…An attempt to synthesize the cyclohexane core of antibiotic abyssomicin C is described. The initial, protecting group-free approach (relying on internal…”
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Synthetic study on the angular triquinanes by Stjepanovic, Mihailo, Jankovic, Aleksandar, Vulovic, Bojan, Matovic, Radomir, Saicic, Radomir

“…The synthesis of an angular triquinane, which could serve as a suitable platform for the synthesis of several natural products (panaginsene, silphinene,…”
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Synthetic studies towards d-modified paclitaxel analogues by Matović Radomir, Saičić Radomir N., Ferjančić Zorana

“…A synthetic sequence has been developed for the preparation of 9,10-O-diacetyl-4-desmethylene-4β-(3-butenyl)-4α-hydroxy-5-O-mesyltaxicin I-1,2-carbonate 3, an…”
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Development of iminosugar-based glycosidase inhibitors as drug candidates for SARS-CoV-2 virus via molecular modelling and in vitro studies by Ferjancic, Zorana, Bihelovic, Filip, Vulovic, Bojan, Matovic, Radomir, Trmcic, Milena, Jankovic, Aleksandar, Pavlovic, Milos, Djurkovic, Filip, Prodanovic, Radivoje, Djurdjevic Djelmas, Aleksandra, Kalicanin, Nevena, Zlatovic, Mario, Sladic, Dusan, Vallet, Thomas, Vignuzzi, Marco, Saicic, Radomir N

“…We developed new iminosugar-based glycosidase inhibitors against SARS-CoV-2. Known drugs (miglustat, migalastat, miglitol, and swainsonine) were chosen as lead…”
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Organocatalyzed Tsuji–Trost reaction: a new method for the closure of five- and six-membered rings by Vulovic, Bojan, Bihelovic, Filip, Matovic, Radomir, Saicic, Radomir N.

“…A combination of organotransition metal catalysis and organocatalysis allows for Tsuji–Trost 5- exo- and 6- exo-cyclizations of aldehydes. This transformation…”
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An aldol approach to the enantioselective synthesis of (-)-oseltamivir phosphate by Trajkovic, Milos, Ferjancic, Zorana, Saicic, Radomir N

“…A formal asymmetric synthesis of the antiviral agent (-)-oseltamivir phosphate is achieved using two aldol reactions as key steps…”
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Radical reactions of xanthates: Annulation of the cyclopentene ring by Elheshi Mohamed Ahmed, Maslak Veselin, Saičić Radomir N.

“…Homoallylic radicals, generated from the corresponding xanthates, react with terminal alkynes to give cyclopentene derivatives in moderate yields…”
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Combining Organocatalyzed Aldolization and Reductive Amination: An Efficient Reaction Sequence for the Synthesis of Iminosugars by Ferjancic, Zorana, Saicic, Radomir N.

“…Over the past two decades, organocatalytic aldol reaction emerged as a powerful method for the enantioselective carbon–carbon bond formation, often offering…”
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Protecting group-free syntheses of natural products and biologically active compounds by Saicic, Radomir N.

“…[Display omitted]…”
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Are science and technology friends or foes? by Glusac, Ksenija D., Saicic, Radomir N.

“…Does the pursuit of scientific research based on a well-defined technological outcome hamper our ability to be creative? And does it limit opportunities to…”
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Total Synthesis of (−)-atrop-Abyssomicin C by Bihelovic, Filip, Saicic, Radomir N.

“…Rolling in the deep: An enantioselective synthesis of a marine antibiotic (−)‐atrop‐abyssomicin C (see scheme) is described. The key steps of the synthetic…”
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Synthesis of vinyldihydropyran by cooperative catalysis by Vulović Bojan, Marić Ivana, Matović Radomir, Saičić Radomir N.

“…5-Unsaturated aldehydes with a suitably positioned allylic halide, or phosphate, leaving group undergo doubly-catalyzed cyclization to give dihydropyran…”
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Cyclization Reactions of Oxyallyl Cation. A Method for Cyclopentane Ring Formation by Vulovic, Bojan, Trmcic, Milena, Matovic, Radomir, Saicic, Radomir N

“…Unsaturated oxyallyl cations with a suitably positioned alkene bond undergo 5-exo-cyclization with the formation of vinylcyclopentane derivatives. Alkyne…”
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Ring Closing Metathesis/Fragmentation Route to (Z)-Configured Medium Ring Cycloalkenes. Total Synthesis of (±)-Periplanone C by Matovic, Radomir, Ivkovic, Aleksandar, Manojlovic, Marija, Tokic-Vujosevic, Zorana, Saicic, Radomir N

“…The combination of ring closing metathesis and β-fragmentation offers an efficient entry into (Z)-configured medium ring cycloalkenes. The fragmentation step…”
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Gold(I)-Catalyzed Domino Cyclizations of Diynes for the Synthesis of Functionalized Cyclohexenone Derivatives. Total Synthesis of (−)-Gabosine H and (−)-6-epi-Gabosine H by Vulovic, Bojan, Kolarski, Dusan, Bihelovic, Filip, Matovic, Radomir, Gruden, Maja, Saicic, Radomir N

“…1,6-Diynes with a t-butylcarbonate group in the propargylic position undergo gold­(I)-catalyzed domino-cyclization which affords α-hydroxycyclohexenones. The…”
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Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone by Trajkovic, Milos, Ferjancic, Zorana, Saicic, Radomir N, Bihelovic, Filip

“…A chiral-pool-based synthesis of the platensimycin core was achieved using (S)-lactic acid as an inexpensive starting material. The cyclohexenone ring was…”
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Enantioselective Synthesis of the Platensimycin Core by Silver(I)‐Promoted Cyclization of Δ6‐α‐Iodoketone by Trajkovic, Milos, Ferjancic, Zorana, Saicic, Radomir N., Bihelovic, Filip

“…A chiral‐pool‐based synthesis of the platensimycin core was achieved using (S)‐lactic acid as an inexpensive starting material. The cyclohexenone ring was…”
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Total Synthesis of ( + )-Swainsonine, (–)- Swainsonine, ( + )-8- epi -Swainsonine and ( + )- Dideoxy-Imino-Lyxitol by an Organocatalyzed Aldolization/Reductive Amination Sequence by Trajkovic, Milos, Pavlovic, Milos, Bihelovic, Filip, Ferjancic, Zorana, Saicic, Radomir N

“…A tactical combination of either (S)- or (R)-proline catalyzed aldol reaction followed by intramolecular reductive amination enabled the synthesis of a chiral…”
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Organocatalyzed Cyclizations of π-Allylpalladium Complexes:  A New Method for the Construction of Five- and Six-Membered Rings by Bihelovic, Filip, Matovic, Radomir, Vulovic, Bojan, Saicic, Radomir N

“…Synergic combination of organotransition metal catalysis and organocatalysis allows, for the first time, the Tsuji−Trost cyclization of aldehydes. A catalytic…”
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Intermolecular free radical additions to strained cycloalkenes. Cyclopropene and cyclobutene as radical acceptors by Ferjančić, Zorana, Čeković, Živorad, Saičić, Radomir N

“…Intermolecular additions of electrophilic radicals to cyclopropene and cyclobutene derivatives afford the addition products in 37–50% yield. The strain relief…”
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