Search Results - "Sahu, Geetaram"

A Novel Therapeutic Approach With Sodium Pyruvate on Vital Signs, Acid–Base, and Metabolic Disturbances in Rats With a Combined Blast and Hemorrhagic Shock by Saha, Biswajit, Sahu, Geetaram, Sharma, Pushpa

“…BackgroundBlast injuries from improvised explosive devices (IEDs) are known to cause blast traumatic brain injuries (bTBIs), hemorrhagic shock (HS), organ…”
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An intrinsically disordered region of the acetyltransferase p300 with similarity to prion-like domains plays a role in aggregation by Kirilyuk, Alexander, Shimoji, Mika, Catania, Jason, Sahu, Geetaram, Pattabiraman, Nagarajan, Giordano, Antonio, Albanese, Christopher, Mocchetti, Italo, Toretsky, Jeffrey A, Uversky, Vladimir N, Avantaggiati, Maria Laura

“…Several human diseases including neurodegenerative disorders and cancer are associated with abnormal accumulation and aggregation of misfolded proteins…”
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p53 Binding to Nucleosomal DNA Depends on the Rotational Positioning of DNA Response Element by Sahu, Geetaram, Wang, Difei, Chen, Claudia B., Zhurkin, Victor B., Harrington, Rodney E., Appella, Ettore, Hager, Gordon L., Nagaich, Akhilesh K.

“…The sequence-specific binding to DNA is crucial for the p53 tumor suppressor function. To investigate the constraints imposed on p53-DNA recognition by…”
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Clinical significance of P53 and Bcl-2 in acute myeloid leukemia patients of Eastern India by Sahu, Geetaram, Jena, Rabindra Kumar

“…The frequency of p53 and Bcl-2 protein expression in 100 newly diagnosed and 10 relapsed acute myeloid leukemia (AML) patients was analyzed by…”
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P-D12 DNA-PK Inhibition Potently Suppress HIV Transcription, Replication and Proviral Reactivation by Tyagi, Mudit, Sahu, Geetaram, Sun, Lin, Bukrinsky, Michael, Simon, Gary

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DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR by Zicari, Sonia, Sharma, Adhikarimayum Lakhikumar, Sahu, Geetaram, Dubrovsky, Larisa, Sun, Lin, Yue, Han, Jada, Tejaswi, Ochem, Alex, Simon, Gary, Bukrinsky, Michael, Tyagi, Mudit

“…Despite reductions in mortality from the use of highly active antiretroviral therapy (HAART), the presence of latent or transcriptionally silent proviruses…”
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SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker by Kolukula, Vamsi K, Sahu, Geetaram, Wellstein, Anton, Rodriguez, Olga C, Preet, Anju, Iacobazzi, Vito, D'Orazi, Gabriella, Albanese, Chris, Palmieri, Ferdinando, Avantaggiati, Maria Laura

“…Mutations of the p53 gene hallmark many human cancers. Several p53 mutant proteins acquire the capability to promote cancer progression and metastasis, a…”
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Real-time imaging reveals endothelium-mediated leukocyte retention in LPS-treated lung microvessels by Kandasamy, Kathirvel, Sahu, Geetaram, Parthasarathi, Kaushik

“…Endotoxemia, a major feature of sepsis, is a common cause of acute lung injury and initiates rapid accumulation of leukocytes in the lung vasculature…”
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Real‐time fluorescence microscopy reveals ICAM‐1‐dependent leukocyte margination in microvessels of LPS‐treated lungs by Kandasamy, Kathirvel, Sahu, Geetaram, Parthasarathi, Kaushik

“…Increased leukocyte migration from lung vessels into airspaces is a hallmark of sepsis. However, specific migration sites and mechanisms remain unclear. Toward…”
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Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-κB and MSK1 and inducing selective epigenetic modifications at HIV-1 LTR by Sahu, Geetaram, Farley, Kalamo, El-Hage, Nazira, Aiamkitsumrit, Benjamas, Fassnacht, Ryan, Kashanchi, Fatah, Ochem, Alex, Simon, Gary L, Karn, Jonathan, Hauser, Kurt F, Tyagi, Mudit

“…Abstract Cocaine accelerates human immunodeficiency virus (HIV-1) replication by altering specific cell-signaling and epigenetic pathways. We have elucidated…”
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Restoration of DNA-binding and growth-suppressive activity of mutant forms of p53 via a PCAF-mediated acetylation pathway by Perez, Ricardo E., Knights, Chad D., Sahu, Geetaram, Catania, Jason, Kolukula, Vamsi K., Stoler, Daniel, Graessmann, Adolf, Ogryzko, Vasily, Pishvaian, Michael, Albanese, Christopher, Avantaggiati, Maria Laura

“…Tumor‐derived mutant forms of p53 compromise its DNA binding, transcriptional, and growth regulatory activity in a manner that is dependent upon the cell‐type…”
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Abstract 66: Corruption of the activity of the mitochondria citrate transporter, CIC, by mutant forms of p53 by Sahu, Geetaram, Rodriguez, Olga Catalina, Kolukula, Vamsi, Catania, Jason, Preet, Anju, Arshed, Arslaan, Albanese, Christopher, Avantaggiati, Maria L.

“…Introduction. A distinctive feature of cancer cells is the implementation of the synthesis of fatty acids (FA), (lipogenesis), which is instead suppressed in…”
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