Search Results - "Sahr, K E"

Mutations of the Red Blood Cell Membrane Proteins: From Clinical Evaluation to Detection of the Underlying Genetic Defect by Palek, Jiri, Sahr, Kenneth E.

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Deletion in Erythrocyte Band 3 Gene in Malaria-Resistant Southeast Asian Ovalocytosis by Jarolim, P, Palek, J, Amato, D, Hassan, K, Sapak, P, Nurse, G T, Rubin, H L, Zhai, S, Sahr, K E, Liu, S C

“…Southeast Asian ovalocytosis (SAO) is a hereditary condition that is widespread in parts of Southeast Asia. The ovalocytic erythrocytes are rigid and resistant…”
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Identification of the proximal erythroid promoter region of the mouse anion exchanger gene by SAHR, K. E, DANIELS, B. P, HANSPAL, M

“…The AE1 gene is expressed in erythrocytes and the A-type intercalated cells of the kidney distal collecting duct. Although the 5' end of the principal…”
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The complete cDNA and polypeptide sequences of human erythroid alpha-spectrin by Sahr, K E, Laurila, P, Kotula, L, Scarpa, A L, Coupal, E, Leto, T L, Linnenbach, A J, Winkelmann, J C, Speicher, D W, Marchesi, V T

“…Overlapping human erythroid alpha-spectrin cDNA clones were isolated from lambda gt11 libraries constructed from cDNAs of human fetal liver and erythroid bone…”
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Disruption of the Mouse μ-Calpain Gene Reveals an Essential Role in Platelet Function by Azam, Mohammad, Andrabi, Shaida S., Sahr, Kenneth E., Kamath, Lakshmi, Kuliopulos, Athan, Chishti, Athar H.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Sequence and exon-intron organization of the DNA encoding the αI domain of human spectrin: application to the study of mutations causing hereditary elliptocytosis by SAHR, K. E, TOBE, T, SCARPA, A, LAUGHINGHOUSE, K, MARCHESI, S. L, AGRE, P, LINNENBACH, A. J, MARCHESI, V. T, FORGET, B. G

“…We have determined the exon-intron organization and the nucleotide sequence of the exons and their flanking intronic DNA in cloned genomic DNA that encodes the…”
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Spectrin cagliari. an Ala–>Gly substitution in helix 1 of beta spectrin repeat 17 that severely disrupts the structure and self-association of the erythrocyte spectrin heterodimer by Sahr, K.E., Coetzer, T.L., Moy, L.S., Derick, L.H., Chishti, A.H., Jarolim, P, Lorenzo, F, Miraglia del Giudice, E, Iolascon, A, Gallanello, R

“…The spectrin tetramer, the principal structural element of the red cell membrane skeleton, is formed by stable head-to-head self-association of two spectrin…”
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Band 3 memphis : a widespread polymorphism with abnormal electrophoretic mobility of erythrocyte band 3 protein caused by substitution AAG→GAG (Lys→Glu) in codon 56 by JAROLIM, P, RUBIN, H. L, SEN ZHAI, SAHR, K. E, SHIH-CHUN LIU, MUELLER, T. J, PALEK, J

“…Band 3 Memphis (b3M) is a variant of the erythrocyte band 3 protein detected in individuals of virtually all ethnic groups and characterized by a reduced…”
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Complete deficiency of glycophorin A in red blood cells from mice with targeted inactivation of the band 3 (AE1) gene by HASSOUN, Y. H, HANADA, T, LUTCHMAN, M, SAHR, K. E, PALEK, J, HANSPAL, M, CHISHTI, A. H

“…Glycophorin A is the major transmembrane sialoglycoprotein of red blood cells. It has been shown to contribute to the expression of the MN and Wright blood…”
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Asynchronous Synthesis of Membrane Skeletal Proteins During Terminal Maturation of Murine Erythroblasts by Hanspal, Manjit, Hanspal, Jatinder S., Kalraiya, Rajiv, Liu, Shiu-Chun, Sahr, Kenneth E., Howard, Don, Palek, Jiri

“…To study the changes in the synthesis of the major membrane skeletal proteins, their assembly on the membrane, and their turnover during terminal red blood…”
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Isolation and chromosomal localization of a novel nonerythroid ankyrin gene by Tse, W T, Menninger, J C, Yang-Feng, T L, Francke, U, Sahr, K E, Lux, S E, Ward, D C, Forget, B G

“…Immunoreactive isoforms of erythrocyte ankyrin have been shown to be present in a variety of nonerythroid tissues. Isolation of the genes that encode these…”
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Molecular Basis of Spectrin Deficiency in Hereditary Pyropoikilocytosis by Hanspal, Manjit, Hanspal, Jatinder S., Sahr, Kenneth E., Fibach, Eitan, Nachman, James, Palek, Jiri

“…Hereditary pyropoikilocytosis (HPP) is a recessively inherited hemolytic anemia characterized by severe poikilo-cytosis and red blood cell fragmentation. HPP…”
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Molecular Cloning of the cDNA for Human Erythrocyte β-Spectrin by Winkelmann, John C., Leto, Thomas L., Watkins, Paul C., Eddy, Roger, Shows, Thomas B., Linnenbach, Alban J., Sahr, Kenneth E., Kathuria, Navneet, Marchesi, Vincent T., Forget, Bernard G.

“…Overlapping cDNA clones, totaling 3.3 kilobases (kb) in length, which encode over 50% of the human erythrocyte β-spectrin subunit, were isolated by antibody…”
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Complete Genomic Organization of the Human Erythroid p55 Gene (MPP1), a Membrane-Associated Guanylate Kinase Homologue by Kim, Anthony C., Metzenberg, Aida B., Sahr, Kenneth E., Marfatia, Shirin M., Chishti, Athar H.

“…Human p55 is an abundantly palmitoylated phosphoprotein of the erythroid membrane. It is the prototype of a newly discovered family of membrane-associated…”
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Erythropoietin enhances the assembly of alpha,beta spectrin heterodimers on the murine erythroblast membranes by increasing beta spectrin synthesis by HANSPAL, M, KALRAIYA, R, HANSPAL, J, SAHR, K. E, PALEK, J

“…Previous biosynthetic studies have revealed that in both mammalian and chicken erythroid cells, alpha spectrin is synthesized in 2-3-fold excess over beta…”
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The structure and organization of the human erythroid anion exchanger (AE1) gene by Sahr, K E, Taylor, W M, Daniels, B P, Rubin, H L, Jarolim, P

“…The AE1 (anion exchanger, band 3) protein is expressed in erythrocytes and in the A-type intercalated cells of the kidney distal collecting tubule. In both…”
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A novel mobile element inserted in the alpha spectrin gene: spectrin dayton. A truncated alpha spectrin associated with hereditary elliptocytosis by Hassoun, H, Coetzer, T L, Vassiliadis, J N, Sahr, K E, Maalouf, G J, Saad, S T, Catanzariti, L, Palek, J

“…Nonviral retrotransposons, retropseudogenes, and short interspersed nuclear elements (SINEs) are mobile DNA segments capable of transposition to new genomic…”
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Identification of the mouse homologue of human discs large and rat SAP97 genes by Lin, Lunhui, Sahr, Kenneth E, H. Chishti, Athar

“…The human homologue of the Drosophila discs large ( dlg) tumor suppressor gene encodes a 926 amino acid protein, hDlg, which is a member of the MAGUK (Membrane…”
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SpαI/78: a mutation of the αI spectrin domain in a white kindred with HE and HPP phenotypes by LECOMTE, M.-C, GARBARZ, M, SAHR, K. E, FORGET, B. G, BOIVIN, P, DHERMY, D, GRANDCHAMP, B, FEO, C, GAUTERO, H, DEVAUX, I, BOURNIER, O, GALAND, C, D'AURIOL, L, GALIBERT, F

“…Limited tryptic digestion of spectrin (Sp) from seven related individuals manifesting hereditary elliptocytosis (HE) or hereditary pyropoikilocytosis (HPP)…”
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Using a histone yellow fluorescent protein fusion for tagging and tracking endothelial cells in ES cells and mice by Fraser, Stuart T., Hadjantonakis, Anna-Katerina, Sahr, Kenneth E., Willey, Stephen, Kelly, Olivia G., Jones, Elizabeth A.V., Dickinson, Mary E., Baron, Margaret H.

“…We report the first endothelial lineage‐specific transgenic mouse allowing live imaging at subcellular resolution. We generated an H2B‐EYFP fusion protein…”
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