Search Results - "Sahr, Allison E"

A Model of Binge-Like Eating Behavior in Mice That Does Not Require Food Deprivation or Stress by Czyzyk, Traci A., Sahr, Allison E., Statnick, Michael A.

“…Binge eating disorder (BED) is characterized by excessive food intake during a short period of time and is often associated with obesity. Mouse models of…”
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LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders by Rorick-Kehn, Linda M., Witkin, Jeffrey M., Statnick, Michael A., Eberle, Elizabeth L., McKinzie, Jamie H., Kahl, Steven D., Forster, Beth M., Wong, Conrad J., Li, Xia, Crile, Robert S., Shaw, David B., Sahr, Allison E., Adams, Benjamin L., Quimby, Steven J., Diaz, Nuria, Jimenez, Alma, Pedregal, Concepcion, Mitch, Charles H., Knopp, Kelly L., Anderson, Wesley H., Cramer, Jeffrey W., McKinzie, David L.

“…Kappa opioid receptors and their endogenous neuropeptide ligand, dynorphin A, are densely localized in limbic and cortical areas comprising the brain reward…”
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Genetic ablation of myelin protein zero-like 3 in mice increases energy expenditure, improves glycemic control, and reduces hepatic lipid synthesis by Czyzyk, Traci A, Andrews, Jessica L, Coskun, Tamer, Wade, Mark R, Hawkins, Eric D, Lockwood, John F, Varga, Gabor, Sahr, Allison E, Chen, Yanyun, Brozinick, Joseph T, Kikly, Kristine, Statnick, Michael A

“…Obesity continues to be a global health problem, and thus it is imperative that new pathways regulating energy balance be identified. Recently, it was…”
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Activation of mesolimbic dopamine neurons during novel and daily limited access to palatable food is blocked by the opioid antagonist LY255582 by Sahr, Allison E, Sindelar, Dana K, Alexander-Chacko, Jesline T, Eastwood, Brian J, Mitch, Charles H, Statnick, Michael A

“…An analog of the trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine series (LY255582) exhibits high in vitro binding affinity and antagonist potency for the mu-,…”
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Multiple subtypes of opioid receptors regulate binge‐like (BE) feeding in rodents on an intermittent access schedule by Statnick, Michael A, Sahr, Allison E, Pintar, John, Czyzyk, Traci

“…Abstract only Binge eating disorder (BED) affects approximately 3% of adults in the USA and is characterized by repeated episodes of eating unusually large…”
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