Search Results - "Sahores, Ana"
-
1
Flurbiprofen inhibits cAMP transport by MRP4/ABCC4 increasing the potency of gemcitabine treatment in PDAC cell models
Published in International journal of biological macromolecules (01-11-2024)“…Pancreatic ductal adenocarcinoma (PDAC) remains a highly malignant cancer with a grim prognosis due to its early metastasis and resistance to current…”
Get full text
Journal Article -
2
Novel, low cost, highly effective, handmade steroid pellets for experimental studies
Published in PloS one (15-05-2013)“…The basic component of Silastic® glue (Dow Corning) used to prepare Silastic® pellets is polydimethylsiloxane. This compound is also present in other…”
Get full text
Journal Article -
3
Inoculated mammary carcinoma-associated fibroblasts: contribution to hormone independent tumor growth
Published in BMC cancer (16-06-2010)“…Increasing evidence has underscored the role of carcinoma associated fibroblasts (CAF) in tumor growth. However, there are controversial data regarding the…”
Get full text
Journal Article -
4
Enhanced Antitumor Immunity via Endocrine Therapy Prevents Mammary Tumor Relapse and Increases Immune Checkpoint Blockade Sensitivity
Published in Cancer research (Chicago, Ill.) (01-03-2021)“…The role of active antitumor immunity in hormone receptor-positive (HR ) breast cancer has been historically underlooked. The aim of this study was to…”
Get full text
Journal Article -
5
Ceefourin-1, a MRP4/ABCC4 inhibitor, induces apoptosis in AML cells enhanced by histamine
Published in Biochimica et biophysica acta. General subjects (01-04-2023)“…Ceefourin-1 is a specific MRP4/ABCC4 inhibitor with potential antileukemic activity. In this study, we evaluate the ability of ceefourin-1 alone or in…”
Get full text
Journal Article -
6
Identification of MRP4/ABCC4 as a Target for Reducing the Proliferation of Pancreatic Ductal Adenocarcinoma Cells by Modulating the cAMP Efflux
Published in Molecular pharmacology (01-07-2019)“…Pancreatic cancer is one of the most lethal types of tumors with no effective therapy available; is currently the third leading cause of cancer in developed…”
Get more information
Journal Article -
7
Progesterone receptor isoform ratio dictates antiprogestin/progestin effects on breast cancer growth and metastases: A role for NDRG1
Published in International journal of cancer (01-05-2022)“…Progesterone receptors (PRs) ligands are being tested in luminal breast cancer. There are mainly two PR isoforms, PRA and PRB, and their ratio (PRA/PRB) may be…”
Get full text
Journal Article -
8
Involvement of histamine H1 and H2 receptor inverse agonists in receptor's crossregulation
Published in European journal of pharmacology (15-03-2019)“…Histamine [2-(4-Imidazolyl)-ethylamine] modulates different biological processes, through histamine H1 and H2 receptors, and their respective blockers are…”
Get full text
Journal Article -
9
MRP4/ABCC4 expression is regulated by histamine in acute myeloid leukemia cells, determining cAMP efflux
Published in The FEBS journal (01-01-2021)“…Intracellular cAMP (i‐cAMP) levels play an important role in acute myeloid leukemia (AML) cell proliferation and differentiation. Its levels are the result of…”
Get full text
Journal Article -
10
Abstract 2959: Changes in the tumor stroma after MFP treatment in a MPA-induced murine mammary carcinoma model
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract The role of the immune system in the regression of mammary carcinomas using endocrine therapies has been poorly investigated. The main goals of this…”
Get full text
Journal Article -
11
Abstract 532: Differential expression of FGFR-1 and -2 in hormone responsive and resistant murine mammary carcinomas
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Fibroblast growth factor (FGF) receptors (FGFRs) are dysregulated in a number of developmental and neoplastic conditions. In human breast cancer…”
Get full text
Journal Article -
12
FGFR3 Down-Regulation is Involved in bacillus Calmette-Guérin Induced Bladder Tumor Growth Inhibition
Published in The Journal of urology (2016)“…Purpose Bacillus Calmette-Guérin is the standard treatment for patients with nonmuscle invasive high histological grade bladder cancer. Previously we found…”
Get full text
Journal Article -
13
Involvement of histamine H 1 and H 2 receptor inverse agonists in receptor's crossregulation
Published in European journal of pharmacology (24-01-2019)“…Histamine [2-(4-Imidazolyl)-ethylamine] modulates different biological processes, through histamine H and H receptors, and their respective blockers are widely…”
Get full text
Journal Article -
14
Associated expressions of FGFR-2 and FGFR-3: from mouse mammary gland physiology to human breast cancer
Published in Breast cancer research and treatment (01-06-2012)“…Fibroblast growth factor receptors (FGFRs) are tyrosine kinase receptors which have been implicated in breast cancer. The aim of this study was to evaluate…”
Get full text
Journal Article -
15
Abstract 542: Inoculated carcinoma associated fibroblasts and hormone independent murine mammary tumor growth
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Murine mammary carcinomas from the MPA-murine breast cancer model express estrogen and progesterone receptors and transit through different stages of…”
Get full text
Journal Article -
16
Mifepristone inhibits MPA-and FGF2-induced mammary tumor growth but not FGF2-induced mammary hyperplasia
Published in Medicina (Buenos Aires) (2010)“…We have previously demonstrated a crosstalk between fibroblast growth factor 2 (FGF2) and progestins inducing experimental breast cancer growth. The aim of the…”
Get full text
Journal Article -
17
Increased High Molecular Weight FGF2 in Endocrine-Resistant Breast Cancer
Published in Hormones & cancer (01-10-2018)“…Endocrine resistance may develop as a consequence of enhanced growth factor signaling. Fibroblast growth factor 2 (FGF2) consists of a low and several high…”
Get full text
Journal Article -
18
The mRNA vaccine for the treatment of pancreatic cancer is here to stay
Published in Medicina (2023)Get more information
Journal Article