Search Results - "Sahinturk, Varol"

High Concentrations of Boric Acid Trigger Concentration-Dependent Oxidative Stress, Apoptotic Pathways and Morphological Alterations in DU-145 Human Prostate Cancer Cell Line by Hacioglu, Ceyhan, Kar, Fatih, Kacar, Sedat, Sahinturk, Varol, Kanbak, Gungor

“…Boric acid is known to regulate the proliferation of cancer cells. Prostate cancer is among the types of cancer with high mortality in men. There are a few…”
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Betaine suppresses cell proliferation by increasing oxidative stress–mediated apoptosis and inflammation in DU-145 human prostate cancer cell line by Kar, Fatih, Hacioglu, Ceyhan, Kacar, Sedat, Sahinturk, Varol, Kanbak, Gungor

“…Prostate cancer is the main cause of cancer-related mortality in men around the world and an important health problem. DU-145 human prostate cancer cells…”
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Protective Effects of Selenium on Cyclophosphamide-Induced Oxidative Stress and Kidney Injury by Gunes, Sibel, Sahinturk, Varol, Uslu, Sema, Ayhanci, Adnan, Kacar, Sedat, Uyar, Ruhi

“…Cyclophosphamide (CP) is a common anticancer drug, but its use in cancer treatment is limited due to its severe toxicities induced mainly by oxidative stress…”
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Investigation of endoplasmic reticulum stress and sonic hedgehog pathway in diabetic liver injury in mice by Sahinturk, Varol, Kacar, Sedat, Sahin, Erhan, Aykanat, Nuriye Ezgi Bektur

“…Diabetes is a common metabolic disease which damages many organs including the liver and causes endoplasmic reticulum (ER) stress, which originates from…”
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The effects of thymoquinone and quercetin on the toxicity of acrylamide in rat glioma cells by Kacar, Sedat, Sahinturk, Varol, Tomsuk, Ozlem, Kutlu, Hatice M.

“…Acrylamide is a neurotoxic agent forming in foods. Thymoquinone and quercetin are plant‐derived antioxidants in various foods with known benefits. C6 cells are…”
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Beta-carotene exerted anti-proliferative and apoptotic effect on malignant mesothelioma cells by Kacar, Sedat, Sariisik, Ediz, Sahinturk, Varol

“…High blood levels of β-carotene and increased intake in the diets are inversely proportional to incidence of many cancer types. Antioxidant activity of…”
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Effect of acrylamide on BEAS-2B normal human lung cells: Cytotoxic, oxidative, apoptotic and morphometric analysis by Kacar, Sedat, Sahinturk, Varol, Kutlu, Hatice Mehtap

“…•Acrylamide induces dose-dependent toxic effect on BEAS-2B normal lung cells.•Apoptotic hallmarks and signs are observable after acrylamide treatment.•Nrf2…”
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The Protective Agents Used against Acrylamide Toxicity: An In Vitro Cell Culture Study-Based Review by Kacar, Sedat, Sahinturk, Varol

“…Acrylamide is a dangerous electrophile with the potency to react with many biological moieties including proteins, and nucleic acids as well as other…”
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The Protective Effects of Silymarin on Thioacetamide-Induced Liver Damage: Measurement of miR-122, miR-192, and miR-194 Levels by Teksoy, Ozgun, Sahinturk, Varol, Cengiz, Mustafa, İnal, Behcet, Ayhancı, Adnan

“…This study aims to investigate the protective effects of silymarin (Sm) in thioacetamide (TAA)-related liver damage. What makes this study special is that it…”
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Protective Effects of Boron on Cyclophosphamide-Induced Bladder Damage and Oxidative Stress in Rats by Ayhanci, Adnan, Tanriverdi, Dondu Tugce, Sahinturk, Varol, Cengiz, Mustafa, Appak-Baskoy, Sila, Sahin, Ilknur Kulcanay

“…This study aims to investigate protective effects of boron against cyclophosphamide-induced bladder toxicity that produces oxidative stress and leads to…”
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Bexarotene inhibits cell proliferation by inducing oxidative stress, DNA damage and apoptosis via PPARγ/ NF-κB signaling pathway in C6 glioma cells by Hacioglu, Ceyhan, Kar, Fatih, Kacar, Sedat, Sahinturk, Varol, Kanbak, Gungor

“…Gliomas are one of the most aggressive brain tumors with a poor prognosis in the central nervous system. Bexarotene is a third-generation retinoid X receptor…”
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Acrylamide exerts its cytotoxicity in NIH/3T3 fibroblast cells by apoptosis by Sahinturk, Varol, Kacar, Sedat, Vejselova, Djanan, Kutlu, Hatice Mehtap

“…Objective: Acrylamide is a chemical utilized in various industries, and many studies have demonstrated its toxicity. The NIH/3T3 mouse embryonic cell line is…”
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Concanavalin A induces apoptosis in a dose‐dependent manner by modulating thiol/disulfide homeostasis in C6 glioblastoma cells by Kar, Fatih, Kacar, Sedat, Hacioglu, Ceyhan, Kanbak, Gungor, Sahinturk, Varol

“…Glioma is the most common brain tumor. C6 rat glioblastoma cells provide the possibility to the scientist to study brain cancer. Concanavalin A (Con A) has a…”
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A mononuclear copper(II) complex containing benzimidazole and pyridyl ligands: Synthesis, characterization, and antiproliferative activity against human cancer cells by Kacar, Sedat, Unver, Hakan, Sahinturk, Varol

“…Metal complexes are recently being hybridized with different moieties to discover new drugs due to their advantageous attributes. Among the metals, copper is a…”
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Silymarin inhibited DU145 cells by activating SLIT2 protein and suppressing expression of CXCR4 by Kacar, Sedat, Bektur Aykanat, Nuriye Ezgi, Sahinturk, Varol

“…Among other cancers, prostate cancer is globally the second most rampant one with the incidence of 29.4% among men. SLIT2/ROBO1 signaling is very crucial…”
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Silver ion‐doped calcium phosphate‐based bone‐graft substitute eliminates chronic osteomyelitis: An experimental study in animals by Köse, Nusret, Asfuroğlu, Zeynel M., Köse, Aydan, Şahintürk, Varol, Gürbüz, Mevlüt, Doğan, Aydın

“…Despite the latest technologies and advances in microbiology and orthopedic surgery, chronic osteomyelitis is still a challenging disorder. Antibiotic…”
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Concentration-Dependent Effects of Zinc Sulfate on DU-145 Human Prostate Cancer Cell Line: Oxidative, Apoptotic, Inflammatory, and Morphological Analyzes by Hacioglu, Ceyhan, Kacar, Sedat, Kar, Fatih, Kanbak, Gungor, Sahinturk, Varol

“…Zinc takes part in several of cellular signaling pathways, containing defense against free radicals, apoptosis, and inflammation. However, interaction between…”
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Cardioprotective Effect of Selenium Against Cyclophosphamide-Induced Cardiotoxicity in Rats by Gunes, Sibel, Sahinturk, Varol, Karasati, Pinar, Sahin, Ilknur Kulcanay, Ayhanci, Adnan

“…The objective of this study is to evaluate the possible protective effects of selenium (Se) against cyclophosphamide (CP)-induced acute cardiotoxicity in rats…”
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Protective effect of carnosic acid on acrylamide‐induced liver toxicity in rats: Mechanistic approach over Nrf2‐Keap1 pathway by Donmez, Dilek B., Kacar, Sedat, Bagci, Ridvan, Sahinturk, Varol

“…Acrylamide is a food contaminant with a range of toxic effects. Carnosic acid (C20H28O4) is a phenolic compound found in plants and has many beneficial…”
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The analysis of boric acid effect on epithelial-mesenchymal transition of CD133 + CD117 + lung cancer stem cells by Semerci Sevimli, Tuğba, Sevimli, Murat, Ghorbani, Aynaz, Şahintürk, Varol, Qomi Ekenel, Emilia, Ertem, Tuğba, Demir Cevizlidere, Bahar, Altuğ, Burcugül, Tomsuk, Özlem, Uysal, Onur, Güneş Bağış, Sibel, Avci, Hüseyin, Çemrek, Fatih, Ahmadova, Zarifa

“…Targeting lung cancer stem cells (LC-SCs) for metastasis may be an effective strategy against lung cancer. This study is the first on epithelial-mesenchymal…”
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