Search Results - "Sahi, J."

Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes by Sahi, J., Hamilton, G., Sinz, M., Barros, S., Huang, S.-M., Lesko, L. J., LeCluyse, E. L.

“…1. Troglitazonewas the first thiazolidinedione approved for clinical use in the treatment of non-insulin-dependent diabetes mellitus. During clinical…”
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Human intestinal anion exchanger isoforms: expression, distribution, and membrane localization by Alrefai, W.A., Tyagi, S., Nazir, T.M., Barakat, J., Anwar, S.S., Hadjiagapiou, C., Bavishi, D., Sahi, J., Malik, P., Goldstein, J., Layden, T.J., Ramaswamy, K., Dudeja, P.K.

“…A family of anion exchangers (AEs) including AE1, AE2 and AE3 has been described. AE3 gene has been shown to encode two alternatively spliced isoforms termed…”
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Ion Transport during Growth and Differentiation by VENKATASUBRAMANIAN, J., SAHI, J., RAO, M. C.

“…: The major function of the adult colon is to reabsorb fluid from the chyme. This ability to conserve salt and water is especially important in newborns, where…”
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Genetic diversity analysis and heterotic grouping of Indian white maize inbred lines using combining ability and SNP markers by Arora, Arushi, Das, Abhijit Kumar, Dixit, Shubhank, KR, Yathish, Singh, S. B., Sekhar, J. C., Ravikesavan, R., Sahi, J. P., Kumar, I. Sudhir, Mahadevu, P., Swain, Digbijaya, Kachapur, R. M., Tuinstra, Mitchell R., Venadan, Sreya, Rakshit, Sujay

“…Maize (Zea mays L.) is a versatile crop with high genetic yield potential and various uses. While yellow maize is primarily used for animal feed, white maize…”
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Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2- Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration by Liu, Houfu, Yu, Na, Lu, Sijie, Ito, Sumito, Zhang, Xuan, Prasad, Bhagwat, He, Enuo, Lu, Xinyan, Li, Yang, Wang, Fei, Xu, Han, An, Gang, Unadkat, Jashvant D, Kusuhara, Hiroyuki, Sugiyama, Yuichi, Sahi, Jasminder

“…Organic anion-transporting polypeptide (OATP) 1A2 has the potential to be a target for central nervous system drug delivery due to its luminal localization at…”
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Chloride transport in primary cultures of rabbit colonocytes at different stages of development by Desai, GN, Sahi, J, Reddy, PM, Venkatasubramanian, J, Vidyasagar, D, Rao, MC

“…BACKGROUND & AIMS: Ontogeny of colonic Cl- transport and its regulation has been characterized inadequately. The aim of this report was to study developmental…”
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Troglitazone induces CYP3A4 in cultured human hepatocytes by LeCluyse, E.L., Sahi, J., Sinz, M., Woolf, T., Hawke, R., Hamilton, G., Lesko, L.J., Huang, S.‐M.

“…Clinical Pharmacology & Therapeutics (1999) 65, 157–157; doi:…”
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Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell line by Mills, Jessica B, Rose, Kelly A, Sadagopan, Nalini, Sahi, Jasminder, de Morais, Sonia M F

“…Induction of drug-metabolizing enzymes and transporters can cause drug-drug interactions and loss of efficacy. In vitro induction studies traditionally use…”
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Evaluation of Hepatotoxic Potential of Drugs by Inhibition of Bile-Acid Transport in Cultured Primary Human Hepatocytes and Intact Rats by Kostrubsky, Vsevolod E., Strom, Stephen C., Hanson, Janean, Urda, Ellen, Rose, Kelly, Burliegh, James, Zocharski, Philip, Cai, Hongbo, Sinclair, Jacqueline F., Sahi, Jasminder

“…Inhibition of canalicular bile acid efflux by medications is associated with clinical liver toxicity, sometimes in the absence of major liver effects in…”
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Comparative Effects of Thiazolidinediones on in Vitro P450 Enzyme Induction and Inhibition by SAHI, Jasminder, BLACK, Christopher B, HAMILTON, Geraldine A, XIANXIAN ZHENG, JOLLEY, Summer, ROSE, Kelly A, GILBERT, Darryl, LECLUYSE, Edward L, SINZ, Michael W

“…Rosiglitazone and pioglitazone are thiazolidinediones used for treatment of noninsulin-dependent diabetes mellitus. These compounds, along with troglitazone,…”
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Avasimibe induces CYP3A4 and multiple drug resistance protein 1 gene expression through activation of the pregnane X receptor by Sahi, Jasminder, Milad, Mark A, Zheng, Xianxian, Rose, Kelly A, Wang, Hongbing, Stilgenbauer, Linda, Gilbert, Darryl, Jolley, Summer, Stern, Ralph H, LeCluyse, Edward L

“…In vitro and clinical studies were conducted to characterize the potential of avasimibe, an acyl-CoA/cholesterol acyltransferase inhibitor to cause drug-drug…”
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Metabolism and transporter-mediated drug–drug interactions of the endothelin-A receptor antagonist CI-1034 by Sahi, Jasminder, Sinz, Michael W., Campbell, Scott, Mireles, Rouchelle, Zheng, Xianxian, Rose, Kelly A., Raeissi, Shamsi, Hashim, Muhammed F., Ye, Yuyang, de Morais, Sonia M., Black, Christopher, Tugnait, Meera, Keller, Laurence H.

“…CI-1034, an endothelin-A receptor antagonist was being developed for pulmonary hypertension. Drug–drug interaction studies using human hepatic microsomes were…”
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Effects of Bergamottin on Human and Monkey Drug-Metabolizing Enzymes in Primary Cultured Hepatocytes by Wen, Yuan Hua, Sahi, Jasminder, Urda, Ellen, Kulkarni, Shaila, Rose, Kelly, Zheng, Xianxian, Sinclair, Jacqueline F, Cai, Hongbo, Strom, Stephen C, Kostrubsky, Vsevolod E

“…We investigated the effect of bergamottin, a major furanocoumarin in grapefruit juice, on phase I and phase II drug-metabolizing enzymes using cultured human…”
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How do Indian culture, liturgy, and theology relate to one another ? by SAHI, J

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The Effect of Bergamottin on Diazepam Plasma Levels and P450 Enzymes in Beagle Dogs by SAHI, Jasminder, REYNER, Eric L, BAUMAN, Jonathan N, GUENEVA-BOUCHEVA, Kristina, BURLEIGH, James E, THOMAS, V. Hayden

“…Bergamottin, a furanocoumarin isolated from grapefruit juice, was investigated for the ability to increase diazepam bioavailability and for its effect on…”
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The azurophilic granules of lymphocytes in the aged by Sahi, J, Stobbe, H, Klatt, R

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Escherichia coli heat-stable enterotoxin-mediated colonic Cl- secretion is absent in cystic fibrosis by Goldstein, J L, Sahi, J, Bhuva, M, Layden, T J, Rao, M C

“…Calcium- and adenosine 3',5'-cyclic monophosphate (cAMP)-mediated Cl- secretions in the human colon are abnormal in cystic fibrosis, but the effect of…”
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Lymphocyte function in the aged by Heine, K M, Stobbe, H, Klatt, R, Sahi, J, Herrmann, H

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Cl- transport in an immortalized human epithelial cell line (NCM460) derived from the normal transverse colon by Sahi, J, Nataraja, S G, Layden, T J, Goldstein, J L, Moyer, M P, Rao, M C

“…Cells of a newly described, immortalized, epithelial, human transverse colonic cell line, NCM460, reach approximately 90% confluence on plastic and develop…”
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Calcium regulated chloride permeabilities in primary cultures of rabbit colonocytes by Sahi, Jasminder, Wiggins, Michael P., Gibori, Gil B., Layden, Thomas J., Rao, Mrinalini C.

“…To determine if calcium‐dependent secretagogues directly act on epithelial cells to elicit CI− secretion, their effects on CI− transport and intracellular Ca2+…”
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