Search Results - "Saheki, Takanobu"
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NMDA Suppresses Pancreatic ABCA1 Expression through the MEK/ERK/LXR Pathway in Pancreatic Beta Cells
Published in Nutrients (27-08-2024)“…Dysfunction or loss of pancreatic β cells can cause insulin deficiency and impaired glucose regulation, resulting in conditions like type 2 diabetes. The…”
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A Pilot Study on the Efficacy of a Diabetic Diet Containing the Rare Sugar D-Allulose in Patients with Type 2 Diabetes Mellitus: A Prospective, Randomized, Single-Blind, Crossover Study
Published in Nutrients (01-06-2023)“…High sugar consumption increases the risk of diabetes, obesity, and cardiovascular diseases. Regarding the diet of patients with diabetes, artificial…”
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3
Successful Therapy Using Pasireotide Long-acting Release for Cushing's Disease Merged with Biochemical Acromegaly
Published in Internal Medicine (01-04-2021)“…It is quite rare that Cushing's disease shows acromegaly, and no pharmacotherapy has yet been discussed. A 21-year-old woman was diagnosed with Cushing's…”
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4
Oxidized LDL Downregulates ABCA1 Expression via MEK/ERK/LXR Pathway in INS-1 Cells
Published in Nutrients (29-08-2021)“…Impaired insulin secretion is one of the main causes of type 2 diabetes. Cholesterol accumulation-induced lipotoxicity contributes to impaired insulin…”
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Effects of 2-Methoxyestradiol, a Main Metabolite of Estradiol on Hepatic ABCA1 Expression in HepG2 Cells
Published in Nutrients (11-01-2022)“…ATP-binding cassette transporter A1 (ABCA1) is a key regulator of lipid efflux, and the absence of ABCA1 induces hepatic lipid accumulation, which is one of…”
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Ectopic Cortisol-producing Adrenocortical Adenoma Detected by 131I-6β-iodomethyl-norcholesterol Scintigraphy
Published in Internal Medicine (15-07-2020)“…A 50-year-old man was referred to our department for overt Cushing's syndrome (CS). His plasma cortisol concentrations were 314 μg/L, and his urinary cortisol…”
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7
Exendin-4 Increases Scavenger Receptor Class BI Expression via Activation of AMPK/FoxO1 in Human Vascular Endothelial Cells
Published in Current issues in molecular biology (03-11-2022)“…Glucagon-like peptide-1 receptor agonist (GLP-1RA) has been clinically proven to protect endothelial function. Previously, we demonstrated that endothelial NO…”
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Role of ATP-binding cassette transporter A1 in suppressing lipid accumulation by glucagon-like peptide-1 agonist in hepatocytes
Published in Molecular metabolism (Germany) (01-04-2020)“…Adenosine triphosphate (ATP)-binding cassette transporter A1 (ABCA1) influences hepatic cholesterol transportation. Accumulation of hepatic cholesterol leads…”
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Co-existing of Neuromyelitis Optica and Fulminant Type 1 Diabetes
Published in Internal Medicine (01-07-2019)“…The patient was a 71-year-old woman with aquaporin-4-antibody positive neuromyelitis optica (NMO), with no history of diabetes. On admission, although she…”
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10
A pilot study on the effect of d-allulose on postprandial glucose levels in patients with type 2 diabetes mellitus during Ramadan fasting
Published in Diabetology and metabolic syndrome (21-06-2022)“…Background During Ramadan fasting, postprandial hyperglycemia is commonly observed after iftar (break of fast at sunset) meal. d-allulose is a rare sugar and…”
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11
Nivolumab-induced hypophysitis followed by acute-onset type 1 diabetes with renal cell carcinoma: a case report
Published in Journal of medical case reports (23-04-2021)“…Immune checkpoint inhibitors have recently become widely used for the management of advanced cancer patients. During the development of immune checkpoint…”
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12
HDL promotes adiponectin gene expression via the CAMKK/CAMKIV pathway
Published in Journal of molecular endocrinology (01-02-2022)“…Adiponectin (APN) is an adipokine that protects against diabetes and atherosclerosis. High-density lipoprotein (HDL) mediates reverse cholesterol transport,…”
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13
Treatment with 2-methoxyestradiol increases endothelial nitric oxide synthase activity via scavenger receptor class BI in human umbilical vein endothelial cells
Published in Molecular human reproduction (01-06-2020)“…Abstract Concentrations of 2-methoxyestradiol (2ME2), a principal metabolite of estradiol, are significantly lower in women with severe preeclampsia. Nitric…”
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14
AGEs inhibit scavenger receptor class B type I gene expression via Smad1 in HUVECs
Published in Journal of molecular endocrinology (01-03-2021)“…Vascular complications are the main cause of morbidity and mortality in diabetic patients, and advanced glycation end products (AGEs) play a critical role in…”
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15
Knowledge of diabetes and the practice of diabetes self-management during Ramadan fasting among patients with type 2 diabetes in Malaysia
Published in Diabetes & metabolic syndrome clinical research & reviews (01-11-2022)“…To assess the level of diabetes knowledge and its association with diabetes self-management practices during Ramadan fasting among patients with type 2…”
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16
Ectopic Cortisol-producing Adrenocortical Adenoma Detected by 131I-6 (-Iodomethyl-norcholesterol Scintigraphy
Published in Internal Medicine (02-04-2020)“…A 50-year-old man was referred to our department for overt Cushing's syndrome (CS). His plasma cortisol concentrations were 314 μg/L, and his urinary cortisol…”
Get full text
Journal Article -
17
Successful Therapy Using Pasireotide Long-acting Release for Cushing's Disease Merged with Biochemical Acromegaly
Published in Internal Medicine (2021)“…It is quite rare that Cushing's disease shows acromegaly, and no pharmacotherapy has yet been discussed. A 21-year-old woman was diagnosed with Cushing's…”
Get full text
Journal Article -
18
A Case of Co-existing of Neuromyelitis Optica and Fulminant Type 1 Diabetes
Published in Internal Medicine (2019)“…The patient was a 71-year-old woman with aquaporin-4-antibody positive neuromyelitis optica (NMO), with no history of diabetes. On admission, although she…”
Get full text
Journal Article