Search Results - "Saheki, Takanobu"

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  1. 1

    NMDA Suppresses Pancreatic ABCA1 Expression through the MEK/ERK/LXR Pathway in Pancreatic Beta Cells by Saheki, Takanobu, Imachi, Hitomi, Fukunaga, Kensaku, Sato, Seisuke, Kobayashi, Toshihiro, Yoshimura, Takafumi, Saheki, Nao, Murao, Koji

    Published in Nutrients (27-08-2024)
    “…Dysfunction or loss of pancreatic β cells can cause insulin deficiency and impaired glucose regulation, resulting in conditions like type 2 diabetes. The…”
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    Journal Article
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    Successful Therapy Using Pasireotide Long-acting Release for Cushing's Disease Merged with Biochemical Acromegaly by Fukunaga, Kensaku, Imachi, Hitomi, Sato, Seisuke, Kobayashi, Toshihiro, Yoshioka, Yuki, Saheki, Takanobu, Ban, Natsuki, Urushihara, Kurumi, Lyu, Jingya, Dong, Tao, Ishikawa, Ryou, Kadota, Kyuichi, Haba, Reiji, Inoshita, Naoko, Murao, Koji

    Published in Internal Medicine (01-04-2021)
    “…It is quite rare that Cushing's disease shows acromegaly, and no pharmacotherapy has yet been discussed. A 21-year-old woman was diagnosed with Cushing's…”
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    Journal Article
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    Oxidized LDL Downregulates ABCA1 Expression via MEK/ERK/LXR Pathway in INS-1 Cells by Lyu, Jingya, Fukunaga, Kensaku, Imachi, Hitomi, Sato, Seisuke, Kobayashi, Toshihiro, Saheki, Takanobu, Ibata, Tomohiro, Yoshimura, Takafumi, Iwama, Hisakazu, Murao, Koji

    Published in Nutrients (29-08-2021)
    “…Impaired insulin secretion is one of the main causes of type 2 diabetes. Cholesterol accumulation-induced lipotoxicity contributes to impaired insulin…”
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    Journal Article
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    Effects of 2-Methoxyestradiol, a Main Metabolite of Estradiol on Hepatic ABCA1 Expression in HepG2 Cells by Ibata, Tomohiro, Lyu, Jingya, Imachi, Hitomi, Fukunaga, Kensaku, Sato, Seisuke, Kobayashi, Toshihiro, Saheki, Takanobu, Yoshimura, Takafumi, Murao, Koji

    Published in Nutrients (11-01-2022)
    “…ATP-binding cassette transporter A1 (ABCA1) is a key regulator of lipid efflux, and the absence of ABCA1 induces hepatic lipid accumulation, which is one of…”
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    Journal Article
  6. 6

    Ectopic Cortisol-producing Adrenocortical Adenoma Detected by 131I-6β-iodomethyl-norcholesterol Scintigraphy by Sato, Seisuke, Imachi, Hitomi, Kobayashi, Toshihiro, Fukunaga, Kensaku, Lyu, Jingya, Dong, Tao, Yoshioka, Yuuki, Saheki, Takanobu, Fukata, Youko, Ban, Natsuki, Urushihara, Kurumi, Kadota, Kyuuichi, Murao, Koji

    Published in Internal Medicine (15-07-2020)
    “…A 50-year-old man was referred to our department for overt Cushing's syndrome (CS). His plasma cortisol concentrations were 314 μg/L, and his urinary cortisol…”
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    Journal Article
  7. 7

    Exendin-4 Increases Scavenger Receptor Class BI Expression via Activation of AMPK/FoxO1 in Human Vascular Endothelial Cells by Lyu, Jingya, Imachi, Hitomi, Fukunaga, Kensaku, Sato, Seisuke, Kobayashi, Toshihiro, Saheki, Takanobu, Japar, Salimah, Iwama, Hisakazu, Matsumura, Yuta, Ozaki, Miyo, Yoshimura, Takafumi, Murao, Koji

    Published in Current issues in molecular biology (03-11-2022)
    “…Glucagon-like peptide-1 receptor agonist (GLP-1RA) has been clinically proven to protect endothelial function. Previously, we demonstrated that endothelial NO…”
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    Journal Article
  8. 8

    Role of ATP-binding cassette transporter A1 in suppressing lipid accumulation by glucagon-like peptide-1 agonist in hepatocytes by Lyu, Jingya, Imachi, Hitomi, Fukunaga, Kensaku, Sato, Seisuke, Kobayashi, Toshihiro, Dong, Tao, Saheki, Takanobu, Matsumoto, Mari, Iwama, Hisakazu, Zhang, Huanxiang, Murao, Koji

    Published in Molecular metabolism (Germany) (01-04-2020)
    “…Adenosine triphosphate (ATP)-binding cassette transporter A1 (ABCA1) influences hepatic cholesterol transportation. Accumulation of hepatic cholesterol leads…”
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    Journal Article
  9. 9

    Co-existing of Neuromyelitis Optica and Fulminant Type 1 Diabetes by Saheki, Takanobu, Imachi, Hitomi, Ibata, Tomohiro, Fukunaga, Kensuke, Yoshioka, Yuki, Kobayashi, Toshihiro, Sato, Seisuke, Mizumoto, Kazuko, Yoshimoto, Takuo, Lyu, Jingya, Dong, Tao, Murao, Koji

    Published in Internal Medicine (01-07-2019)
    “…The patient was a 71-year-old woman with aquaporin-4-antibody positive neuromyelitis optica (NMO), with no history of diabetes. On admission, although she…”
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    Journal Article
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    Nivolumab-induced hypophysitis followed by acute-onset type 1 diabetes with renal cell carcinoma: a case report by Kikuchi, Fumi, Saheki, Takanobu, Imachi, Hitomi, Kobayashi, Toshihiro, Fukunaga, Kensaku, Ibata, Tomohiro, Sato, Seisuke, Ban, Natsuki, Lyu, Jingya, Japar, Salimah, Murao, Koji

    Published in Journal of medical case reports (23-04-2021)
    “…Immune checkpoint inhibitors have recently become widely used for the management of advanced cancer patients. During the development of immune checkpoint…”
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    Journal Article
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    HDL promotes adiponectin gene expression via the CAMKK/CAMKIV pathway by Kobayashi, Toshihiro, Imachi, Hitomi, Fukunaga, Kensaku, Lyu, Jingya, Sato, Seisuke, Saheki, Takanobu, Ibata, Tomohiro, Matsumoto, Mari, Japar, Salimah B, Murao, Koji

    Published in Journal of molecular endocrinology (01-02-2022)
    “…Adiponectin (APN) is an adipokine that protects against diabetes and atherosclerosis. High-density lipoprotein (HDL) mediates reverse cholesterol transport,…”
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    Journal Article
  13. 13

    Treatment with 2-methoxyestradiol increases endothelial nitric oxide synthase activity via scavenger receptor class BI in human umbilical vein endothelial cells by Dong, Tao, Sato, Seisuke, Lyu, Jingya, Imachi, Hitomi, Kobayashi, Toshihiro, Fukunaga, Kensaku, Saheki, Takanobu, Iwama, Hisakazu, Zhang, Guoxing, Murao, Koji

    Published in Molecular human reproduction (01-06-2020)
    “…Abstract Concentrations of 2-methoxyestradiol (2ME2), a principal metabolite of estradiol, are significantly lower in women with severe preeclampsia. Nitric…”
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    Journal Article
  14. 14

    AGEs inhibit scavenger receptor class B type I gene expression via Smad1 in HUVECs by Nagata, Hiromi, Lyu, Jingya, Imachi, Hitomi, Fukunaga, Kensaku, Sato, Seisuke, Kobayashi, Toshihiro, Saheki, Takanobu, Seo, Kayoko, Salimah, Japar B, Iwama, Hisakazu, Sakamoto, Ryuichi, Ogawa, Yoshihiro, Murao, Koji

    Published in Journal of molecular endocrinology (01-03-2021)
    “…Vascular complications are the main cause of morbidity and mortality in diabetic patients, and advanced glycation end products (AGEs) play a critical role in…”
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    Journal Article
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    Ectopic Cortisol-producing Adrenocortical Adenoma Detected by 131I-6 (-Iodomethyl-norcholesterol Scintigraphy by Sato, Seisuke, Imachi, Hitomi, Kobayashi, Toshihiro, Fukunaga, Kensaku, Lyu, Jingya, Dong, Tao, Yoshioka, Yuuki, Saheki, Takanobu, Fukata, Youko, Natsuki, Ban, kurumi, Urushihara, Kadota, Kyuuichi, Murao, Koji

    Published in Internal Medicine (02-04-2020)
    “…A 50-year-old man was referred to our department for overt Cushing's syndrome (CS). His plasma cortisol concentrations were 314 μg/L, and his urinary cortisol…”
    Get full text
    Journal Article
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    A Case of Co-existing of Neuromyelitis Optica and Fulminant Type 1 Diabetes by Saheki, Takanobu, Imachi, Hitomi, Ibata, Tomohiro, Fukunaga, Kensuke, Yoshioka, Yuki, Kobayashi, Toshihiro, Sato, Seisuke, Mizumoto, Kazuko, Yoshimoto, Takuo, Lyu, Jingya, Dong, Tao, Murao, Koji

    Published in Internal Medicine (2019)
    “…The patient was a 71-year-old woman with aquaporin-4-antibody positive neuromyelitis optica (NMO), with no history of diabetes. On admission, although she…”
    Get full text
    Journal Article