Search Results - "Sahay, Shashwat"
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A review of databases predicting the effects of SNPs in miRNA genes or miRNA-binding sites
Published in Briefings in bioinformatics (21-05-2019)“…Abstract Modern precision medicine comprises the knowledge and understanding of individual differences in the genomic sequence of patients to provide…”
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The genomic and transcriptional landscape of primary central nervous system lymphoma
Published in Nature communications (10-05-2022)“…Primary lymphomas of the central nervous system (PCNSL) are mainly diffuse large B-cell lymphomas (DLBCLs) confined to the central nervous system (CNS)…”
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Reference-free deconvolution, visualization and interpretation of complex DNA methylation data using DecompPipeline, MeDeCom and FactorViz
Published in Nature protocols (01-10-2020)“…DNA methylation profiling offers unique insights into human development and diseases. Often the analysis of complex tissues and cell mixtures is the only…”
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SSAM-lite: A Light-Weight Web App for Rapid Analysis of Spatially Resolved Transcriptomics Data
Published in Frontiers in genetics (28-02-2022)“…The combination of a cell's transcriptional profile and location defines its function in a spatial context. Spatially resolved transcriptomics (SRT) has…”
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5'isomiR-183-5p|+2 elicits tumor suppressor activity in a negative feedback loop with E2F1
Published in Journal of experimental & clinical cancer research (02-06-2022)“…MicroRNAs (miRNAs) and isomiRs play important roles in tumorigenesis as essential regulators of gene expression. 5'isomiRs exhibit a shifted seed sequence…”
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