Search Results - "Sahariah, Priyanka"
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The Effect of Molecular Weight on the Antibacterial Activity of N , N , N -Trimethyl Chitosan (TMC)
Published in International journal of molecular sciences (09-04-2019)“…, , -trimethyl chitosan (TMC) with 93% degree of trimethylation was synthesized. TMC and the chitosan starting material were subjected to acidic hydrolysis to…”
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Impact of Chain Length on Antibacterial Activity and Hemocompatibility of Quaternary N‑Alkyl and N,N‑Dialkyl Chitosan Derivatives
Published in Biomacromolecules (11-05-2015)“…A highly efficient method for chemical modification of chitosan biopolymers by reductive amination to yield N,N-dialkyl chitosan derivatives was developed. The…”
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3
Antimicrobial peptide shows enhanced activity and reduced toxicity upon grafting to chitosan polymers
Published in Chemical communications (Cambridge, England) (25-07-2015)“…Here we report that grafting of a short antimicrobial peptide, anoplin, to chitosan polymers is a strategy for abolishing the hemolytic propensity, and at the…”
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The effect of substituent, degree of acetylation and positioning of the cationic charge on the antibacterial activity of quaternary chitosan derivatives
Published in Marine drugs (21-08-2014)“…A series of water-soluble cationic chitosan derivatives were prepared by chemoselective functionalization at the amino group of five different parent chitosans…”
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Antibacterial properties of poly ( N , N -dimethylaminoethyl methacrylate) obtained at different initiator concentrations in solution polymerization
Published in Royal Society open science (01-01-2022)“…The samples of poly( , -dimethylaminoethyl methacrylate) were synthesized by radical polymerization. The amount of monomer and solvent was constant as opposed…”
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Efficient synthesis of chitosan derivatives as clickable tools
Published in European polymer journal (05-03-2022)“…[Display omitted] •Efficient synthesis of alkynoyl chitosan derivatives having different spacers.•Direct N-modification of chitosan with good control of…”
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Antimicrobial Chitosan and Chitosan Derivatives: A Review of the Structure–Activity Relationship
Published in Biomacromolecules (13-11-2017)“…This review gives an updated overview of the current state-of-the-art for antimicrobial chitosan and chitosan derivatives and the effects of structural…”
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Quaternary Ammoniumyl Chitosan Derivatives for Eradication of Staphylococcus aureus Biofilms
Published in Biomacromolecules (10-09-2018)“…Bacterial biofilms tolerate extreme levels of antibiotics. Treatment of biofilm infections therefore requires the development of new or modified antimicrobials…”
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Structure-activity relationship for antibacterial chitosan carrying cationic and hydrophobic moieties
Published in Carbohydrate polymers (15-07-2023)“…To overcome the problem of antibiotic resistance and toxicity of synthetic polymers, herein we report the synthesis of biocompatible polymers which can serve…”
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Chitosan-hydroxycinnamic acid conjugates: Optimization of the synthesis and investigation of the structure activity relationship
Published in Carbohydrate polymers (01-02-2022)“…A new synthesis method was developed and optimized by a full factorial design for conjugating hydroxycinnamic acids (HCA-s) to chitosan. Cinnamic acid and…”
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Synthetic strategy for selective N-modified and O-modified PEGylated chitosan derivatives
Published in European polymer journal (01-08-2016)“…[Display omitted] •mPEGs were introduced selectively at two reactive centers of the biopolymer chitosan.•TBDMS-protection aided in synthesis of N-mPEG chitosan…”
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In vitro biological response of human osteoblasts in 3D chitosan sponges with controlled degree of deacetylation and molecular weight
Published in Carbohydrate polymers (15-02-2021)“…•Sponges were created from chitosan batches with varying degree of deacetylation and molecular weight by freeze-drying.•All the chitosan sponges revealed…”
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Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
Published in Biomacromolecules (13-04-2020)“…In this study we have developed biodegradable polymeric nanoparticles (NPs) containing the cytostatic drugs mertansine (MRT) or cabazitaxel (CBZ). The NPs are…”
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Synthesis of guanidinylated chitosan with the aid of multiple protecting groups and investigation of antibacterial activity
Published in Carbohydrate polymers (20-08-2015)“…•Guanidinylated chitosan derivatives were synthesized utilizing two different protecting groups.•Reactions in organic medium enabled quantitative…”
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Aroylated phenylenediamine HO53 modulates innate immunity, histone acetylation and metabolism
Published in Molecular immunology (01-03-2023)“…In the current context of antibiotic resistance, the need to find alternative treatment strategies is urgent. Our research aimed to use synthetized aroylated…”
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Derivatized chitosan-oil-in-water nanocapsules for trans-cinnamaldehyde delivery
Published in International journal of biological macromolecules (15-06-2023)“…trans-Cinnamaldehyde, known for its bacterial anti-quorum sensing activity when applied at sublethal concentrations, has gained traction given its potential…”
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Solving the antibacterial resistance in Europe: The multipronged approach of the COST Action CA21145 EURESTOP
Published in Drug resistance updates (01-05-2024)Get full text
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Utilization of TBDMS chitosan for synthesis of photoactive chitosan derivatives and application in photografting on ophthalmic lens material
Published in Reactive & functional polymers (01-08-2020)“…Three photoactive chitosan derivatives were synthesized using TBDMS chitosan as the starting material. In this study, we also report an optimized method for…”
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N,N,N-trimethyl chitosan as an efficient antibacterial agent for polypropylene and polylactide nonwovens
Published in Journal of the Textile Institute (03-06-2017)“…The paper presents a method of depositing N,N,N-trimethyl chitosan (TMC) layers onto polypropylene and polylactide nonwovens. A two-step modification procedure…”
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