Search Results - "Sahar, Najam Us"
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Synthesis, kinetic mechanism and docking studies of vanillin derivatives as inhibitors of mushroom tyrosinase
Published in Bioorganic & medicinal chemistry (01-09-2015)“…[Display omitted] The purpose of the present study was to discover the extent of contribution to antityrosinase activity by adding hydroxy substituted benzoic…”
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Kinetic and in silico studies of novel hydroxy-based thymol analogues as inhibitors of mushroom tyrosinase
Published in European journal of medicinal chemistry (15-06-2015)“…The present studies reports the synthesis of hydoxylated thymol analogues (4a–e) and (6a–c) as mushroom tyrosinase inhibitors. The title compounds were…”
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In Vitro Antiviral Activity of Cinnamomum cassia and Its Nanoparticles Against H7N3 Influenza A Virus
Published in Journal of microbiology and biotechnology (01-01-2016)“…Nanoparticles have wide-scale applications in various areas, including medicine, chemistry, electronics, and energy generation. Several physical, biological,…”
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Large-Scale in Vitro Transcription, RNA Purification and Chemical Probing Analysis
Published in Cellular physiology and biochemistry (01-08-2018)“…Abstract Background/Aims: RNA elements such as catalytic RNA, riboswitch, microRNA, and long non coding RNA (lncRNA) play central roles in many cellular…”
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Protein sequence conservation and stable molecular evolution reveals influenza virus nucleoprotein as a universal druggable target
Published in Infection, genetics and evolution (01-08-2015)“…[Display omitted] •Influenza virus nucleoprotein can serve as a universal target for antiviral drug development.•On analyzing over 22,000 sequences, 95% length…”
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Nexus Between Financial Crises, Corporate Governance and Future Stock Price Crash Risk
Published in SAGE open (01-10-2022)“…We aim to investigate the impact of corporate governance attributes on future stock price crash risk in stable and crisis periods. We used Dynamic Panel…”
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Prevalence of rotavirus, adenovirus, hepatitis A virus and enterovirus in water samples collected from different region of Peshawar, Pakistan
Published in Annals of Agricultural and Environmental Medicine (01-01-2016)“…Viral gastroenteritis and other water-borne diseases are the most neglected areas of research in Pakistan. To determine the quality of water, 4 enteric viruses…”
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Global geno-proteomic analysis reveals cross-continental sequence conservation and druggable sites among influenza virus polymerases
Published in Antiviral research (01-12-2014)“…•Polymorphism analyses reveal 12% and 6% conservation among viral polymerase nucleotide and protein sequences resp.•Identified 29 conserved nucleotide regions…”
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Regulation of core expression during the hepatitis C virus life cycle
Published in Journal of general virology (01-02-2015)“…Core plays a critical role during hepatitis C virus (HCV) assembly, not only as a structural component of the virion, but also as a regulator of the formation…”
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Dengue fever in the Indian Subcontinent: an overview
Published in Journal of infection in developing countries (26-04-2011)“…The Indian Subcontinent has emerged as a scene of many mosquito-borne infectious diseases, including malaria and dengue fever. After the 1990s, the rate of…”
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Frequency of hepatitis E and Hepatitis A virus in water sample collected from Faisalabad, Pakistan
Published in Annals of Agricultural and Environmental Medicine (01-01-2015)“…Hepatitis E and Hepatitis A virus both are highly prevalent in Pakistan mainly present as a sporadic disease. The aim of the current study is to isolate and…”
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An exploratory research on the role of family in youth's drug addiction
Published in Health psychology & behavioral medicine (01-01-2014)“…Most of the researches in Pakistan are concerned with the aetiological factors of drug addiction among the youth. However, few studies seek to explore the…”
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Logical Analysis of Regulation of Interleukin-12 Expression Pathway Regulation During HCV Infection
Published in Protein and peptide letters (2016)“…Hepatitis C virus (HCV) triggers coordinated innate and adaptive response in host cell. HCV genome and proteins of the replicating virus are recognized as…”
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Development and Fabrication of Carbon Nanotube (CNT)/CuO Nanocomposite for Volatile Organic Compounds (VOCs) Gas Sensor Application
Published in Macromolecular symposia. (01-12-2021)“…Volatile organic compounds (VOCs) have been recognized as one of the primary trace segments of atmospheric air pollutants. The change in the level of VOCs in…”
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Red Blood Cell Substitutes: Liposome Encapsulated Hemoglobin and Magnetite Nanoparticle Conjugates as Oxygen Carriers
Published in International journal of molecular sciences (13-01-2023)“…The established blood donation and transfusion system has contributed a lot to human health and welfare, but for this system to function properly, it requires…”
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Exploring the inhibitory potential of Nigella sativa against dengue virus NS2B/NS3 protease and NS5 polymerase using computational approaches
Published in RSC advances (15-06-2023)“…Dengue fever, a highly infectious and rapidly spreading vector borne illness, is classified as a Neglected Tropical Disease (NTD) by WHO because they generally…”
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Production of avian influenza virus vaccine using primary cell cultures generated from host organs
Published in Journal of industrial microbiology & biotechnology (01-06-2013)“…The global availability of a therapeutically effective influenza virus vaccine during a pandemic remains a major challenge for the biopharmaceutical industry…”
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Engineering Modified mRNA-Based Vaccine against Dengue Virus Using Computational and Reverse Vaccinology Approaches
Published in International journal of molecular sciences (11-11-2022)“…Dengue virus belonging to the family and its four serotypes are responsible for dengue infections, which extend over 60 countries in tropical and subtropical…”
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Formulation optimization, in vitro and in vivo evaluation of agomelatine-loaded nanostructured lipid carriers for augmented antidepressant effects
Published in Colloids and surfaces, B, Biointerfaces (01-08-2022)“…The present study was intended to prepare and optimize agomelatine-loaded nanostructured lipid carriers (AGM-NLCs) for augmented in vivo antidepressant…”
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PCR-Based Molecular Diagnosis of Hepatitis Virus (HBV and HDV) in HCV Infected Patients and Their Biochemical Study
Published in Journal of pathogens (01-01-2016)“…Seroprevalence of HCV indicates that HCV is found in more than 10% of HBV- or HDV-infected patients worldwide leading to liver disease. Here we show HBV and…”
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