Subcellular distribution of coronary dilatatory protein-hormonal complexes in rat hypothalamus

We previously reported the presence of a group of coronary dilatatory protein-carriers of the cardioactive neurohormones and precursors of bioactive compounds in the hypothalamus of some animals. Investigation of the subcellular distribution of those proteins revealed their localization in neurosecr...

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Bibliographic Details
Published in:	Neurochemical research Vol. 6; no. 12; pp. 1299 - 1307
Main Authors:	Srapionian, R M, Sahakian, F M, Galoyan, A A
Format:	Journal Article
Language:	English
Published:	United States 01-12-1981
Subjects:	Animals Carrier Proteins - metabolism Cats Coronary Circulation - drug effects Hypothalamus - analysis Microscopy, Electron Rats Rats, Inbred Strains Subcellular Fractions - analysis Synaptosomes - analysis Tissue Distribution Vasodilator Agents - metabolism
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Summary:	We previously reported the presence of a group of coronary dilatatory protein-carriers of the cardioactive neurohormones and precursors of bioactive compounds in the hypothalamus of some animals. Investigation of the subcellular distribution of those proteins revealed their localization in neurosecretory granules and in synaptosomes of the hypothalamus. In further investigation of the regional distribution of coronary-active proteins in different parts of the brain they were found in synaptosomes of the cerebral cortex too. The main location of coronary-active proteins in synaptosomes indicates their participation in synaptic functions.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0364-3190 1573-6903
DOI:	10.1007/BF00964351