Search Results - "Sahafi, Flora"

Phenotypic Characterization of the Immune Landscape in the Bone Marrow of Patients with Acute Myeloid Leukemia (AML) Using MultiOmyxTM Hyperplexed Immunofluorescence Assay by Au, Qingyan, Hanifi, Arezoo, Parnell, Erinn, Kuo, Judy, Leones, Eric, Sahafi, Flora, Nagy, Mate, William, Josette

“…Background: Acute myeloid leukemia (AML) is a clinically and molecularly heterogeneous disorder. Bone marrow (BM) constitutes the home niche for leukemia cells…”
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Abstract 408: Reduction of tumor-infiltrating B cells linked to recurrence of NSCLC tumors by Juncker-Jensen, Anna, Stavrou, Nicholas, Nagy, Mate, Parnell, Erinn, Kuo, Judy, Leones, Eric, Pham, Kathy, Sahafi, Flora

“…Abstract Introduction: Lung cancer is the leading cause of cancer related mortality worldwide. Non-small cell lung cancer (NSCLC), accounting for approximately…”
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Abstract 2092: Tumor-infiltrating myeloid cells: Using MultiOmyx to distinguish between TAMs, TANs, and MDSCs in the pancreatic tumor microenvironment by Juncker-Jensen, Anna, Hoe, Nicholas, Kuo, Judy, Au, Qingyan, Zhu, Shijun, Leones, Eric, Sahafi, Flora

“…Abstract Myeloid cells are the primary recruited effector cells during inflammation. A subset of these, consisting primarily of tumor-associated M1/M2…”
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Characterization of Immunosuppressive Cells Using MultiOmyx in Hematological Malignancies by Au, Qingyan, Hanafi, Arezoo, Parnell, Erinn, Kuo, Judy, Leones, Eric, Sahafi, Flora, Padmanabhan, Raghavkrishna, Hoe, Nicholas, William, Josette

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MO3-13-6 [Encore]Characterization of Immunosuppressive Cells Using MultiOmyx in Hematological Malignancies by Au, Qingyan, Hanafi, Arezoo, Parnell, Erinn, Kuo, Judy, Leones, Eric, Sahafi, Flora, Padmanabhan, Raghavkrishna, Hoe, Nicholas, William, Josette

“…Abstract Background Tumor associated macrophages (TAM) and myeloid-derived suppressor cells (MDSC) can assist tumors to escape immune surveillance within the…”
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Abstract 497: Characterization of TIGIT expression using MultiOmyxTM hyperplexed immunofluorescence assay in solid tumors by Au, Qingyan, Hanifi, Arezoo, Parnell, Erinn, Kuo, Judy, Leones, Eric, Sahafi, Flora, Pham, Kathy, Padmanabhan, RaghavKrishna, Hoe, Nicholas, William, Josette

“…Abstract TIGIT (T cell immunoreceptor with Ig and ITIM domains) is a recently identified immune-receptor that is expressed on T cells, natural killer (NK)…”
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Abstract 1175: A pro-tumorigenic mechanism of M2 tumor-associated macrophages in triple-negative breast cancer by Juncker-Jensen, Anna, Stavrou, Nicholas, Padmanabhan, Raghav, Parnell, Erinn, Kuo, Judy, Leones, Eric, Sahafi, Flora, William, Josette

“…Abstract Introduction: Triple-negative breast cancers (TNBCs) are defined as tumors that are negative for both estrogen, progesterone and HER-2 receptors. It…”
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Using a multiplexed immunofluorescence approach to compare immune cell populations in subtypes of non-small cell lung cancer by Juncker-Jensen, Anna, Reddy, Vivek, Parnell, Erinn, Nagy, Mate Levente, Kuo, Judy, Leones, Eric, Sahafi, Flora, Hoe, Nicholas, William, Josette

“…Abstract only e20702 Background: Non-small cell lung cancer (NSCLC) accounts for approximately 80-85% of all lung cancer cases, and is characterized by a poor…”
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Characterization of Myeloid-Derived Suppressor Cells and Tumor Associated Macrophages Using MultiOmyxTM Hyperplexed Immunofluorescence Assay in Hodgkin Lymphoma by Au, Qingyan, Fang, Jun, Juncker-Jensen, Anna, Kuo, Judy, Leones, Eric, Sahafi, Flora, Padmanabhan, RaghavKrishna, Hoe, Nicholas, William, Josette

“…Tumor microenvironment (TME) consists of heterogeneous subsets of myeloid cells and plays a crucial role in promoting cancer development and metastasis. Tumor…”
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Abstract 94: Interrogation of STING induced cytokines in the tumor microenvironment using an Integrated MultiOmyx-RNAscope panel for spatial and quantitative profiling by Lam, Sandra, Todorov, Courtney, Fei, Jiong, Nunns, Harry, Leones, Eric, Thio, Marianne, Sahafi, Flora, Parnell, Erinn, Au, Qingyan

“…Abstract The STING (Stimulator of Interferon Genes) pathway is a pivotal player in the innate immune response, responsible for detecting cytosolic accumulation…”
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Abstract 4578: Quantification of protein complexes and post-translational modifications in colorectal cancer utilizing combinted MultiOmyxTM and PLA assay from a single FFPE slide by Au, Qingyan, Sahafi, Flora, Nguyen, Kathy, Padmanabhan, Raghav, Moler, Edward J., Hoe, Nicholas

“…Abstract A comprehensive signaling pathway analysis is critical to characterize cancer pathogenesis, in which malignant cells evolve from nonmalignant cells,…”
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Abstract 4688: Comprehensive analysis of natural killer cell-associated markers using MultiOmyxTM immunofluorescence assay by Parnell, Erinn A., Fei, Jiong, Nunns, Harry, Leones, Eric, Yeung, Elaine, Russell, Blair, Sahafi, Flora, Au, Qingyan

“…Abstract As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have recently gained attention as an important type of…”
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Abstract 4696: Characterizing CD39 and CD73 cell subtypes in the tumor microenvironment using MultiOmyx by Todorov, Courtney, Gallagher, Kevin, Wortman, Juliana, Nunns, Harry, Parnell, Erinn, Leones, Eric, Yeung, Elaine, Russell, Blair, Sahafi, Flora, Au, Qingyan

“…Abstract CD39 and CD73 are membrane bound enzymes that function together to convert extracellular adenosine 5’-triphospate (ATP)/adenosine diphosphate (ADP)…”
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Abstract 5487: Improved spatial biology analysis of the tumor microenvironment with the next generation of the MultiOmyxTMplatform by Lazare, Michael, Nunns, Harry, Moghaddam, Fatemeh Jelvhei, Jin, Xiaowei, Todorov, Courtney, Leones, Eric, Thio, Marianne, Sahafi, Flora, Parnell, Erinn, Au, Qingyan

“…Abstract Multiplexed Immunofluorescence is a powerful tool for spatially characterizing and phenotyping cells within the tumor microenvironment. MultiOmyx has…”
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Abstract 1705: Spatial interrogation of tertiary lymphoid structures (TLS) in colorectal carcinoma (CRC) tumor microenvironment (TME) using the MultiOmyx࣪ assay by Nunns, Harry, Parnell, Erinn A., Lazare, Michael, Kuo, Judy, Leones, Eric, Sahafi, Flora, William, Josette, Au, Qingyan

“…Abstract Immune checkpoint blockade (ICB) therapy has revolutionized the landscape of cancer therapy in multiple tumor types since Ipilimumab, the first ICB…”
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