Search Results - "Saha Roy, Sudipa"

Role of Estrogen Receptor Signaling in Breast Cancer Metastasis by Saha Roy, Sudipa, Vadlamudi, Ratna K.

“…Metastatic breast cancer is a life-threatening stage of cancer and is the leading cause of death in advanced breast cancer patients. Estrogen signaling and the…”
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Therapeutic Targeting of PELP1 Prevents Ovarian Cancer Growth and Metastasis by CHAKRAVARTY, Dimple, SAHA ROY, Sudipa, RAM BABU, Challa, DANDAMUDI, Rajasekhar, CURIEL, Tyler J, VIVAS-MEJIA, Pablo, LOPEZ-BERESTEIN, Gabriel, SOOD, Anil K, VADLAMUDI, Ratna K

“…Ovarian cancer remains a major threat to women's health, partly due to difficulty in early diagnosis and development of metastases. A critical need exists to…”
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Inhibition of mTOR signaling reduces PELP1-mediated tumor growth and therapy resistance by Gonugunta, Vijay K, Sareddy, Gangadhara R, Krishnan, Samaya Rajeshwari, Cortez, Valerie, Roy, Sudipa Saha, Tekmal, Rajeshwar Rao, Vadlamudi, Ratna K

“…Proline, Glutamic acid-, and Leucine-rich Protein 1 (PELP1) is a proto-oncogene that modulates estrogen receptor (ER) signaling. PELP1 expression is…”
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Therapeutic use of quercetin in the control of infection and anemia associated with visceral leishmaniasis by Sen, Gargi, Mandal, Suparna, Saha Roy, Sudipa, Mukhopadhyay, Sibabrata, Biswas, Tuli

“…Flavonoids are a broad class of plant phenolics that are known to possess a well-established protective effect against membrane lipoperoxidative damages…”
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Oxidation of hemoglobin and redistribution of band 3 promote erythrophagocytosis in visceral leishmaniasis by Saha Roy, Sudipa, Chowdhury, Kaustav Dutta, Sen, Gargi, Biswas, Tuli

“…In visceral leishmaniasis (VL), oxidative assault on erythrocytes perturbs their cellular environment and makes them vulnerable to premature hemolysis. In this…”
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Abstract 1431: Therapeutic exploitation of mutant BRAF in childhood glioma by Roy, Sudipa Saha, Shackleford, Terry, Houghton, Peter

“…Abstract Low grade gliomas (LGG) are the most common tumors of the central nervous system in children, accounting for about 50% of all brain tumors. They…”
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Significance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancer by Roy, S S, Gonugunta, V K, Bandyopadhyay, A, Rao, M K, Goodall, G J, Sun, L-Z, Tekmal, R R, Vadlamudi, R K

“…Tumor metastasis is the leading cause of death among breast cancer patients. PELP1 (proline, glutamic acid and leucine rich protein 1) is a nuclear receptor…”
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Abstract 1464: Significance and therapeutic potential of PELP1 axis in ER-negative breast cancer by Vadlamudi, Ratna K., Roy, Sudipa Saha

“…Abstract The molecular basis of breast cancer progression to metastasis remains poorly understood. Even though ER and PR explain the biology of ER-positive…”
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Novel role of PELP1 in regulating chemotherapy response in mutant p53-expressing triple negative breast cancer cells by Krishnan, Samaya R., Nair, Binoj C., Sareddy, Gangadhara R., Roy, Sudipa Saha, Natarajan, Mohan, Suzuki, Takayoshi, Peng, Yan, Raj, Ganesh, Vadlamudi, Ratna K.

“…Triple-negative breast cancer (TNBC), the most aggressive breast cancer subtype, occurs in younger women and is associated with poor prognosis…”
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Abstract 2301: Epigenetic regulation of microRNA-200a and 141 by proto-oncogene PELP1: Role in breast cancer progression and metastasis by Roy, Sudipa Saha, Rao, Manjeet, Sun, Luzhe, Tekmal, Rajeshwar Rao, Vadlamudi, Ratna K.

“…Abstract Endocrine therapy is a key component of adjuvant therapy for estrogen receptor (ER)-positive breast cancer. However, initial or acquired resistance…”
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Significance of PELP1 in ER-negative breast cancer metastasis by Roy, Sudipa, Chakravarty, Dimple, Cortez, Valerie, De Mukhopadhyay, Keya, Bandyopadhyay, Abhik, Ahn, Jung-Mo, Raj, Ganesh V, Tekmal, Rajeshwar R, Sun, LuZhe, Vadlamudi, Ratna K

“…Breast cancer metastasis is a major clinical problem. The molecular basis of breast cancer progression to metastasis remains poorly understood. PELP1 is an…”
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Abstract 958: PELP1 regulation of mTOR Axis: Role in breast cancer progression and resistance by Gonugunta, Vijaya Kumar, Valerie, Cortez, Roy, Sudipa Saha, Sareddy, Gangadhar Reddy, Nair, Binoj C., Vadlamudi, Ratna K.

“…Abstract Hormonal therapy resistance is a major clinical problem. Emerging evidence suggests that estrogen (ER) participates in extra-nuclear signaling events…”
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Role of sulfhydryl groups in band 3 in the inhibition of phosphate transport across erythrocyte membrane in visceral leishmaniasis by Roy, Sudipa Saha, Sen, Gargi, Biswas, Tuli

“…Membrane destabilization in erythrocytes plays an important role in the premature hemolysis and development of anemia during visceral leishmaniasis (VL)…”
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Abstract 2628: BU32: A novel proteasome inhibitor for treatment of multiple myeloma and other types of cancer by ROY, SUDIPA SAHA, KIRMA, NAMEER, NAIR, HAREESH, TEKMAL, RAJESHWAR RAO, AGYIN, JOSEPH

“…Abstract Background: Multiple myeloma (MM) is an incurable neoplasm characterized by devastating and progressive bone destruction. Standard chemotherapeutic…”
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