Search Results - "Saha, Debarya"
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Uncoupling of mTORC1 from E2F activity maintains DNA damage and senescence
Published in Nature communications (24-10-2024)“…DNA damage is a primary trigger for cellular senescence, which in turn causes organismal aging and is a promising target of anti-aging therapies. Most DNA…”
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SMARCA4 biology in alveolar rhabdomyosarcoma
Published in Oncogene (10-03-2022)“…Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and phenocopies a muscle precursor that fails to undergo terminal differentiation…”
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First person – Hardik P. Gala and Debarya Saha
Published in Journal of cell science (01-08-2022)“…ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career…”
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A transcriptionally repressed quiescence program is associated with paused RNA polymerase II and is poised for cell cycle re-entry
Published in Journal of cell science (01-08-2022)“…ABSTRACT Adult stem cells persist in mammalian tissues by entering a state of reversible quiescence, referred to as G0, which is associated with low levels of…”
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